Patents by Inventor James C. DiNunzio
James C. DiNunzio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230256401Abstract: A blender includes a proximal section having a proximal upper housing and a proximal lower housing, a distal section having a distal upper housing and a distal lower housing, at least one intermediate section disposed between the proximal section and the distal section and coupleable thereto, each of the at least one intermediate section including an intermediate upper housing and an intermediate lower housing, a shaft extending through the proximal section, the distal section and the at least one intermediate section, and at least one blade disposed on the shaft.Type: ApplicationFiled: April 26, 2021Publication date: August 17, 2023Applicant: Merck Sharp & Dohme LLCInventors: William Blincoe, James C. DiNunzio, M. Sebastian Escotet Espinoza, Sung Woo Kim, Graciela Terife
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Publication number: 20230172949Abstract: Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can be further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.Type: ApplicationFiled: July 25, 2022Publication date: June 8, 2023Applicants: BOARD OF REGENTS, THE UNIVERISTY OF TEXAS SYSTEM, AustinPx, LLCInventors: Chris BROUGH, James W. MCGINITY, Dave A. MILLER, James C. DINUNZIO, Robert O. WILLIAMS, III
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Patent number: 11439650Abstract: Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can be further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.Type: GrantFiled: May 5, 2020Date of Patent: September 13, 2022Assignees: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, DISPERSOL TECHNOLOGIES, LLCInventors: Chris Brough, James W. McGinity, Dave A. Miller, James C. DiNunzio, Robert O. Williams, III
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Publication number: 20200261473Abstract: Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can he further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.Type: ApplicationFiled: May 5, 2020Publication date: August 20, 2020Applicants: BOARD OF REGENTS, THE UNIVERISTY OF TEXAS SYSTEM, DISPERSOL TECHNOLOGIES, LLCInventors: Chris BROUGH, James W. MCGINITY, Dave A. MILLER, James C. DINUNZIO, Robert O. WILLIAMS, III
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Patent number: 10668085Abstract: Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can be further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.Type: GrantFiled: June 19, 2018Date of Patent: June 2, 2020Assignees: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, DISPERSOL TECHNOLOGIES, LLCInventors: Chris Brough, James W. McGinity, Dave A. Miller, James C. DiNunzio, Robert O. Williams, III
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Patent number: 10426782Abstract: The invention relates to a pharmaceutical composition comprising Compound 1 or a pharmaceutically acceptable salt thereof for the treatment of cancer and a process for its preparation. The invention also relates to administering the pharmaceutical composition to a patient according to an intermittent dosing regimen.Type: GrantFiled: March 26, 2015Date of Patent: October 1, 2019Assignee: MILLENNIUM PHARMACEUTICALS, INC.Inventors: Rachael L. Brake, Viviana Bozon, Ching-Kuo J. Chow, James C. Dinunzio, Katherine M. Galvin, Karuppiah Kannan, Yuki Kodono, Qunli Xu
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Publication number: 20180360850Abstract: Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can be further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.Type: ApplicationFiled: June 19, 2018Publication date: December 20, 2018Applicants: BOARD OF REGENTS, THE UNIVERISTY OF TEXAS SYSTEM, DISPERSOL TECHNOLOGIES, LLCInventors: Chris BROUGH, James W. MCGINITY, Dave A. MILLER, James C. DINUNZIO, Robert O. WILLIAMS, III
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Patent number: 10022385Abstract: Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can be further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.Type: GrantFiled: May 13, 2016Date of Patent: July 17, 2018Assignees: Board of Regents, The University of Texas System, DisperSol Technologies, LLCInventors: Chris Brough, James W. McGinity, Dave A. Miller, James C. Dinunzio, Robert O. Williams, III
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Publication number: 20170173033Abstract: The invention relates to a pharmaceutical composition comprising Compound 1 or a pharmaceutically acceptable salt thereof for the treatment of cancer and a process for its preparation. The invention also relates to administering the pharmaceutical composition to a patient according to an intermittent dosing regimen.Type: ApplicationFiled: March 26, 2015Publication date: June 22, 2017Inventors: Rachael L. BRAKE, Viviana BOZON, Ching-Kuo J. CHOW, James C. DINUNZIO, Katherine M. GALVIN, Karuppiah KANNAN, Yuki KODONO, Qunli XU
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Publication number: 20160250230Abstract: Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can be further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.Type: ApplicationFiled: May 13, 2016Publication date: September 1, 2016Applicants: BOARD OF REGENTS, THE UNIVERISTY OF TEXAS SYSTEM, DISPERSOL TECHNOLOGIES, LLCInventors: Chris BROUGH, James W. MCGINITY, Dave A. MILLER, James C. DINUNZIO, Robert O. WILLIAMS, III
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Patent number: 9339440Abstract: Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can be further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.Type: GrantFiled: July 15, 2013Date of Patent: May 17, 2016Assignees: Board of Regents, the University of Texas System, DisperSol Technologies, LLCInventors: Chris Brough, James W. McGinity, Dave A. Miller, James C. DiNunzio, Robert O. Williams, III
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Publication number: 20130303630Abstract: Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can be further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.Type: ApplicationFiled: July 15, 2013Publication date: November 14, 2013Inventors: Chris Brough, James W. McGinity, Dave A. Miller, James C. DiNunzio, Robert O. Williams, III
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Publication number: 20090053315Abstract: Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can be further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.Type: ApplicationFiled: August 21, 2008Publication date: February 26, 2009Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Chris Brough, James W. McGinity, Dave A. Miller, James C. DiNunzio, Robert O. Williams