Patents by Inventor James C. Hannis

James C. Hannis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODIFIED NUCLEIC ACIDS FOR NANOPORE ANALYSIS
    Publication number: 20180164280
    Abstract: Provided herein is technology relating to nanopore analysis of nucleic acids and particularly, but not exclusively, to compositions, methods, systems, and kits for analysis of nucleic acids or other assays comprising nucleic acid components.
    Type: Application
    Filed: November 6, 2017
    Publication date: June 14, 2018
    Inventors: David J. Ecker, Stanley T. Motley, James C. Hannis, Lara G. Krieg, Todd P. Michael, David D. Duncan, Shane G. Poplawski, Thomas N. Chiesl
  • Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy
    Patent number: 9752184
    Abstract: The present invention provides methods for rapid forensic analysis of mitochondrial DNA and methods for characterizing heteroplasmy of mitochondrial DNA, which can be used to assess the progression of mitochondrial diseases.
    Type: Grant
    Filed: August 11, 2014
    Date of Patent: September 5, 2017
    Assignee: IBIS BIOSCIENCES, INC.
    Inventors: David J. Ecker, Richard H. Griffey, Rangarajan Sampath, Steven A. Hofstadler, John McNeil, Stanley T. Crooke, Lawrence B. Blyn, Thomas A. Hall, Yun Jiang, James C. Hannis, Neill K. White, Vivek Samant, Mark W. Eshoo, Jared J. Drader
  • Compositions and methods for inhibiting terminal transferase activity
    Patent number: 9752173
    Abstract: The present invention realtes to systems and methods for amplifying nucleic acid. In particular, systems and methods are provided for inhibiting polymerase based terminal transferase activity within a polynucleotide amplification setting (e.g., polymerase chain reaction). In addition, systems and methods are provided for generating amplified products generated with polynucleotide amplification techniques having reduced 3? non-templated nucleotide addition.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: September 5, 2017
    Assignee: IBIS BIOSCIENCES, INC.
    Inventors: Sherilynn Manalili Wheeler, James C. Hannis, Steven A. Hofstadler
  • SYSTEMS FOR BIOAGENT IDENTIFICATION
    Publication number: 20160145676
    Abstract: The present invention provides systems and methods for analysis of samples, particularly biological and environmental sample to detect biomolecules of interest contained therein. A variety of system components are described herein, including, but not limited to, components for sample handling, mixing of materials, sample processing, transfer of materials, and analysis of materials. The invention further provides mechanisms for combining and integrating the different components and for housing, moving, and storing system components or the system as a whole. The systems may include any one or more or all of these components. The system finds particular use when employed for analysis of nucleic acid molecule using mass spectrometry, however, the invention is not limited such specific uses.
    Type: Application
    Filed: November 20, 2015
    Publication date: May 26, 2016
    Inventors: Steven A. Hofstadler, Jose R. Gutierrez, James C. Hannis, Jared J. Drader, Rex O. Bare, Jeffrey C. Smith, Paul J. Gleason, Jared Nathanson, Ronald K. Bergold, Robert D. Miller, Kevin S. Oberkramer
  • APPARATUSES FOR STERILELY DELIVERING FLUID
    Publication number: 20160116379
    Abstract: Provided herein are apparatuses, systems, kits and methods for sterilely delivering fluid to an elongated swab. In particular, provided herein are apparatuses configured to sterilely deliver a desired fluid to a swab contained within a swab housing.
    Type: Application
    Filed: October 22, 2015
    Publication date: April 28, 2016
    Inventors: James C. Hannis, Sherilynn Manalili Wheeler, Thomas N. Chiesl, Jared J. Drader, Steven A. Hofstadler, Ronald K. Bergold, Paul J. Gleason, Zachary T. Hannis
  • IONIZATION PROBE ASSEMBLIES
    Publication number: 20160104610
    Abstract: The invention relates generally to sample ionization, and provides ionization probe assemblies, systems, computer program products, and methods useful for this purpose.
    Type: Application
    Filed: October 19, 2015
    Publication date: April 14, 2016
    Inventors: Steven A. Hofstadler, Jose R. Gutierrez, James C. Hannis, Jared J. Drader, Rex O. Bare, Jeffrey C. Smith, Paul J. Gleason, Jared Nathanson
  • COMPOSITIONS AND METHODS FOR INHIBITING TERMINAL TRANSFERASE ACTIVITY
    Publication number: 20150376671
    Abstract: The present invention realtes to systems and methods for amplifying nucleic acid. In particular, systems and methods are provided for inhibiting polymerase based terminal transferase activity within a polynucleotide amplification setting (e.g., polymerase chain reaction). In addition, systems and methods are provided for generating amplified products generated with polynucleotide amplification techniques having reduced 3? non-templated nucleotide addition.
    Type: Application
    Filed: June 29, 2015
    Publication date: December 31, 2015
    Inventors: Sherilynn Manalili Wheeler, James C. Hannis, Steven A. Hofstadler
  • Systems for bioagent indentification
    Patent number: 9194877
    Abstract: The present invention provides systems and methods for analysis of samples, particularly biological and environmental sample to detect biomolecules of interest contained therein. A variety of system components are described herein, including, but not limited to, components for sample handling, mixing of materials, sample processing, transfer of materials, and analysis of materials. The invention further provides mechanisms for combining and integrating the different components and for housing, moving, and storing system components or the system as a whole. The systems may include any one or more or all of these components. The system finds particular use when employed for analysis of nucleic acid molecule using mass spectrometry, however, the invention is not limited such specific uses.
    Type: Grant
    Filed: July 15, 2010
    Date of Patent: November 24, 2015
    Assignee: IBIS BIOSCIENCES, INC.
    Inventors: Steven A. Hofstadler, Jose R. Gutierrez, James C. Hannis, Jared J. Drader, Rex O. Bare, Jeffrey C. Smith, Paul J. Gleason, Jared Nathanson, Ronald K. Bergold, Robert D. Miller, Kevin S. Oberkramer
  • Ionization probe assemblies
    Patent number: 9165740
    Abstract: The invention relates generally to sample ionization, and provides ionization probe assemblies, systems, computer program products, and methods useful for this purpose.
    Type: Grant
    Filed: August 4, 2014
    Date of Patent: October 20, 2015
    Assignee: IBIS BIOSCIENCES, INC.
    Inventors: Steven A. Hofstadler, Jose R. Gutierrez, James C. Hannis, Jared J. Drader, Rex O. Bare, Jeffrey C. Smith, Paul J. Gleason, Jared Nathanson
  • METHODS FOR RAPID DETECTION AND IDENTIFICATION OF BIOAGENTS IN EPIDEMIOLOGICAL AND FORENSIC INVESTIGATIONS
    Publication number: 20150225780
    Abstract: The present invention provides methods for rapid forensic investigations by identification of bioagents associated with biowarfare and acts of terrorism or crime. The methods are also useful for epidemiological investigations by genotyping of bioagents.
    Type: Application
    Filed: October 21, 2013
    Publication date: August 13, 2015
    Inventors: David J. Ecker, Richard H. Griffey, Rangarajan Sampath, Steven A. Hofstadler, John McNeil, Stanley T. Crooke, James C. Hannis
  • Compositions and methods for inhibiting terminal transferase activity
    Patent number: 9068017
    Abstract: The present invention relates to systems and methods for amplifying nucleic acid. In particular, systems and methods are provided for inhibiting polymerase based terminal transferase activity within a polynucleotide amplification setting (e.g., polymerase chain reaction). In addition, systems and methods are provided for generating amplified products generated with polynucleotide amplification techniques having reduced 3? non-templated nucleotide addition.
    Type: Grant
    Filed: April 6, 2011
    Date of Patent: June 30, 2015
    Assignee: IBIS BIOSCIENCES, INC.
    Inventors: Sherilynn Manalili Wheeler, James C. Hannis, Steven A. Hofstadler
  • METHODS FOR RAPID FORENSIC ANALYSIS OF MITOCHONDRIAL DNA AND CHARACTERIZATION OF MITOCHONDRIAL DNA HETEROPLASMY
    Publication number: 20150031117
    Abstract: The present invention provides methods for rapid forensic analysis of mitochondrial DNA and methods for characterizing heteroplasmy of mitochondrial DNA, which can be used to assess the progression of mitochondrial diseases.
    Type: Application
    Filed: August 11, 2014
    Publication date: January 29, 2015
    Inventors: David J. Ecker, Richard H. Griffey, Rangarajan Sampath, Steven A. Hofstadler, John McNeil, Stanley T. Crooke, Lawrence B. Blyn, Thomas A. Hall, Yun Jiang, James C. Hannis, Neill K. White, Vivek Samant, Mark W. Eshoo, Jared J. Drader
  • IONIZATION PROBE ASSEMBLIES
    Publication number: 20150014548
    Abstract: The invention relates generally to sample ionization, and provides ionization probe assemblies, systems, computer program products, and methods useful for this purpose.
    Type: Application
    Filed: August 4, 2014
    Publication date: January 15, 2015
    Inventors: Steven A. Hofstadler, Jose R. Gutierrez, James C. Hannis, Jared J. Drader, Rex O. Bare, Jeffrey C. Smith, Paul J. Gleason, Jared Nathanson
  • Method for rapid detection and identification of bioagents in epidemiological and forensic investigations
    Patent number: 8815513
    Abstract: The present invention provides methods for rapid forensic investigations by identification of bioagents associated with biowarfare and acts of terrorism or crime. The methods are also useful for epidemiological investigations by genotyping of bioagents.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: August 26, 2014
    Assignee: Ibis Biosciences, Inc.
    Inventors: David J. Ecker, Richard H. Griffey, Rangarajan Sampath, Steven A. Hofstadler, John McNeil, Stanley T. Crooke, James C. Hannis
  • Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy
    Patent number: 8802372
    Abstract: The present invention provides methods for rapid forensic analysis of mitochondrial DNA and methods for characterizing heteroplasmy of mitochondrial DNA, which can be used to assess the progression of mitochondrial diseases.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: August 12, 2014
    Assignee: Ibis Biosciences, Inc.
    Inventors: David J. Ecker, Richard H. Griffey, Rangarajan Sampath, Steven A. Hofstadler, John McNeil, Stanley T. Crooke, Lawrence Blyn, Thomas A. Hall, Yun Jiang, James C. Hannis, Neill White, Vivek Samant, Mark W. Eshoo, Jared James Drader
  • Ionization probe assemblies
    Patent number: 8796617
    Abstract: The invention relates generally to sample ionization, and provides ionization probe assemblies, systems, computer program products, and methods useful for this purpose.
    Type: Grant
    Filed: January 3, 2012
    Date of Patent: August 5, 2014
    Assignee: Ibis BioSciences, Inc.
    Inventors: Steven A. Hofstadler, Jose R. Gutierrez, James C. Hannis, Jared J. Drader, Rex O. Bare, Jeffrey C. Smith, Paul J. Gleason, Jared Nathanson
  • Methods for identifying bioagents
    Patent number: 8563250
    Abstract: The present invention provides methods for rapid forensic investigations by identification of bioagents associated with biowarfare and acts of terrorism or crime. The methods are also useful for epidemiological investigations by genotyping of bioagents.
    Type: Grant
    Filed: March 5, 2007
    Date of Patent: October 22, 2013
    Assignee: Ibis Biosciences, Inc.
    Inventors: David J. Ecker, Richard H. Griffey, Rangarajan Sampath, Steven Hofstadler, John McNeil, Stanley T. Crooke, James C. Hannis
  • Methods for identifying bioagents
    Patent number: 8268565
    Abstract: The present invention provides methods for rapid forensic analysis of mitochondrial DNA and methods for characterizing heteroplasmy of mitochondrial DNA, which can be used to assess the progression of mitochondrial diseases.
    Type: Grant
    Filed: December 2, 2008
    Date of Patent: September 18, 2012
    Assignee: Ibis Biosciences, Inc.
    Inventors: David J. Ecker, Richard H. Griffey, Rangarajan Sampath, Stephen A. Hofstadler, John McNeil, Stanley T. Crooke, Lawrence B. Blyn, Thomas A. Hall, Yun Jiang, James C. Hannis, Neill White, Vivek Samant, Mark W. Eshoo, Jared J. Drader
  • COMPOSITIONS FOR USE IN IDENTIFICATION OF SALMONELLA
    Publication number: 20120190016
    Abstract: The present invention relates generally to identification of Salmonella enterica bacteria or strains of Salmonella enterica, and provides methods, compositions and kits useful for this purpose when combined, for example, with molecular mass or base composition analysis.
    Type: Application
    Filed: March 17, 2010
    Publication date: July 26, 2012
    Applicant: Ibis Biosciences, Inc
    Inventors: Rangarajan Sampath, Feng Li, Sherilynn Manalili Wheeler, James C. Hannis
  • Method for Rapid Detection and Identification of Bioagents in Epidemiological and Forensic Investigations
    Publication number: 20120171679
    Abstract: The present invention provides methods for rapid forensic investigations by identification of bioagents associated with biowarfare and acts of terrorism or crime. The methods are also useful for epidemiological investigations by genotyping of bioagents.
    Type: Application
    Filed: October 31, 2007
    Publication date: July 5, 2012
    Applicant: Ibis Biosciences, Inc.
    Inventors: David J. Ecker, Richard H. Griffey, Rangarajan Sampath, Steven A. Hofstadler, John McNeil, Stanley T. Crooke, James C. Hannis