Patents by Inventor James C. Iatridis

James C. Iatridis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IIMPROVED APPROACH TO REPAIR TISSUE DEFECTS BY BONDING INJECTABLE GELS TO NATIVE SOFT TISSUES
    Publication number: 20230158210
    Abstract: Systems, methods, and kits are described for repairing a fibrocartilage defect in a subject. The fibrocartilage defect is contacted with a first composition containing an oxidized and methacrylated glycosaminoglycan to form an imine bond between the glycosaminoglycan and the fibrocartilage defect, thereby coating the fibrocartilage defect with the glycosaminoglycan. The fibrocartilage defect coated with the glycosaminoglycan is then contacted with a mixture of a pre-polymer hydrogel composition containing a first crosslinking unit that, when polymerized, is capable of bonding to methacrylate and a hydrogel polymerization initiator composition, thereby forming a hydrogel that is covalently bonded to the glycosaminoglycan through methacrylate.
    Type: Application
    Filed: October 30, 2020
    Publication date: May 25, 2023
    Inventors: Tyler J. DISTEFANO, James C. IATRIDIS
  • Genipin cross-linked fibrin gels
    Patent number: 8968725
    Abstract: The invention provides a genipin cross-linked fibrin gel. The ratio of genipin to fibrin in the gel ranges from about 0.1:1 to about 10:1 (genipin:fibrin). The gel can be hydrogel. Also provided is method for repairing tissue defects by administering the gel to site of tissue defect.
    Type: Grant
    Filed: December 2, 2011
    Date of Patent: March 3, 2015
    Assignee: University of Vermont and State Agricultural College
    Inventors: Rachel Schek, Arthur J. Michalek, James C. Iatridis
  • METHOD OF REPAIRING A TISSUE DEFECT USING GENIPIN CROSS-LINKED FIBRIN GELS
    Publication number: 20150004138
    Abstract: The invention provides a genipin cross-linked fibrin gel. The ratio of genipin to fibrin in the gel ranges from about 0.1:1 to about 10:1 (genipin:fibrin). The gel can be hydrogel. The gel further contains proteins from the extracellular matrix that promote cell growth and density in and around the gel. Also provided is method for repairing tissue defects by administering the gel to site of tissue defect.
    Type: Application
    Filed: September 11, 2014
    Publication date: January 1, 2015
    Inventors: James C. Iatridis, Clare Canal Guterl
  • GENIPIN CROSS-LINKED FIBRIN GELS
    Publication number: 20130345321
    Abstract: The invention provides a genipin cross-linked fibrin gel. The ratio of genipin to fibrin in the gel ranges from about 0.1:1 to about 10:1 (genipin:fibrin). The gel can be hydrogel. The gel further contains proteins from the extracellular matrix that promote cell growth and density in and around the gel. Also provided is method for repairing tissue defects by administering the gel to site of tissue defect.
    Type: Application
    Filed: May 31, 2013
    Publication date: December 26, 2013
    Inventors: James C. Iatridis, Clare Canal Guterl
  • GENIPIN CROSS-LINKED FIBRIN GELS
    Publication number: 20120189584
    Abstract: The invention provides a genipin cross-linked fibrin gel. The ratio of genipin to fibrin in the gel ranges from about 0.1:1 to about 10:1 (genipin:fibrin). The gel can be hydrogel. Also provided is method for repairing tissue defects by administering the gel to site of tissue defect.
    Type: Application
    Filed: December 2, 2011
    Publication date: July 26, 2012
    Applicant: University of Vermont and State Agricultural College
    Inventors: Rachel Schek, Arthur J. Michalek, James C. Iatridis