Patents by Inventor James C. Jenson

James C. Jenson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of binding between proteins and macromolecular ligands
    Publication number: 20020182650
    Abstract: Disclosed is a compound which inhibits binding between a target protein and a macromolecular ligand of the target protein. The compound comprises a targeting group, an attaching group and, optionally a linker group. In one aspect of the invention, the targeting group is a moiety that binds non-covalently to a surface of the target protein with a Kd of greater than about 0.1 &mgr;M and within sufficient proximity to the target protein/macromolecular ligand binding site to inhibit binding between the target protein and the macromolecular ligand. In another aspect of the invention, targeting group is degradable in vivo. In yet another aspect of the invention, the compound comprises a linker group that is cleavable in vivo.
    Type: Application
    Filed: February 22, 2002
    Publication date: December 5, 2002
    Applicant: Polaris Pharmaceuticals, Inc.
    Inventors: Michael Sworin, James C. Jenson
  • Assays for identifiying compounds that bind to the gastrin releasing peptide receptor
    Patent number: 5741651
    Abstract: The invention discloses a procedure for the preparation of the solubilized and purified gastrin releasing peptide receptor, in an active form, from a gastrin releasing peptide receptor source such as Swiss 3T3 fibroblasts. The invention also discloses a method of using the solubilized gastrin releasing peptide receptor in drug screening assays to identify compounds having suitable binding affinity for the gastrin releasing peptide receptor.
    Type: Grant
    Filed: January 26, 1994
    Date of Patent: April 21, 1998
    Assignee: Berlex Biosciences
    Inventors: Richard I. Feldman, James C. Jenson
  • Solubilization and purification of the active gastrin releasing peptide receptor
    Patent number: 5591831
    Abstract: A procedure for the preparation of the solubilized and purified gastrin releasing peptide receptor, in an active form, from a gastrin releasing peptide receptor source such as Swiss 3T3 fibroblasts.
    Type: Grant
    Filed: January 25, 1994
    Date of Patent: January 7, 1997
    Assignee: Berlex Laboratories, Inc.
    Inventors: Richard I. Feldman, James M. Wu, Elaina Mann, Anne Larocca, James C. Jenson
  • Solubilization and purification of the active gastrin releasing peptide receptor
    Patent number: 5215963
    Abstract: A procedure for the preparation of the solubilized and purified gastrin releasing peptide receptor, in an active form, from a gastrin releasing peptide receptor source such as Swiss 3T3 fibroblasts.
    Type: Grant
    Filed: October 24, 1989
    Date of Patent: June 1, 1993
    Assignee: Berlex Laboratories, Inc.
    Inventors: Richard I. Feldman, James M. Wu, Elaina Mann, Anne Larocca, James C. Jenson