Patents by Inventor James C. Mikkelsen, Jr.
James C. Mikkelsen, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9207249Abstract: The present invention is an automated microfluidic chip processing apparatus that includes a deck for holding at least one microfluidic chip and capable of being accessed by a liquid handling system, a fluid control system, and a detection system, wherein a chip handling device transports the chip from the deck to the fluid control system and the detection system. The present invention also includes a chip for use with an automated microfluidic chip processing apparatus, and a method for processing a microfluidic chip using such an apparatus.Type: GrantFiled: July 29, 2013Date of Patent: December 8, 2015Assignee: Caliper Life Sciences, Inc.Inventors: Michael Greenstein, Colin B Kennedy, James C Mikkelsen, Jr.
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Publication number: 20130315781Abstract: The present invention is an automated microfluidic chip processing apparatus that includes a deck for holding at least one microfluidic chip and capable of being accessed by a liquid handling system, a fluid control system, and a detection system, wherein a chip handling device transports the chip from the deck to the fluid control system and the detection system. The present invention also includes a chip for use with an automated microfluidic chip processing apparatus, and a method for processing a microfluidic chip using such an apparatus.Type: ApplicationFiled: July 29, 2013Publication date: November 28, 2013Applicant: CALIPER LIFE SCIENCES, INC.Inventors: Michael Greenstein, Colin B. Kennedy, James C. Mikkelsen, JR.
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Patent number: 8496875Abstract: The present invention is an automated microfluidic chip processing apparatus that includes a deck for holding at least one microfluidic chip and capable of being accessed by a liquid handling system, a fluid control system, and a detection system, wherein a chip handling device transports the chip from the deck to the fluid control system and the detection system. The present invention also includes a chip for use with an automated microfluidic chip processing apparatus, and a method for processing a microfluidic chip using such an apparatus.Type: GrantFiled: May 20, 2005Date of Patent: July 30, 2013Assignee: Caliper Life Sciences, Inc.Inventors: Michael Greenstein, Colin B. Kennedy, James C. Mikkelsen, Jr.
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Patent number: 7070681Abstract: A novel electrokinetic instability (EKI) micromixer and method takes advantage of the EKI to effect active rapid stirring of confluent microstreams of biomolecules without moving parts or complex microfabrication processes. The EKI is induced using an alternating current (A/C) electric field. Within seconds, the randomly fluctuating, three-dimensional velocity field created by the EKI rapidly and effectively stirs an initially heterogeneous solution and generates a homogeneous solution that is useful in a variety of biochemical and bioanalytical systems. Microfabricated on a glass substrate, the inventive EKI micromixer can be easily and advantageously integrated in molecular diagnostics apparatuses and systems, such as a chip-based “Lab-on-a-Chip” microfluidic device.Type: GrantFiled: January 24, 2002Date of Patent: July 4, 2006Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Juan G. Santiago, Michael H. Oddy, James C. Mikkelsen, Jr.
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Patent number: 6703074Abstract: A display comprised of a first component containing spheres encapsulated within a wax, and thereover and thereunder said component substrates.Type: GrantFiled: March 12, 2002Date of Patent: March 9, 2004Assignee: Xerox CorporationInventors: Guerino G. Sacripante, James C. Mikkelsen, Jr.
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Patent number: 6559820Abstract: A display is provided with an insulative layer with electrical properties which have been selected so that the display can be addressed with a stylus and which minimizes the effects of stray triboelectrically generated charges. Also provided is a method of addressing such a display by depositing charges on a surface of the display, maintaining sufficient charge to effect an image change, and then removing the charges.Type: GrantFiled: November 24, 1999Date of Patent: May 6, 2003Assignee: Xerox CorporationInventors: James C. Mikkelsen, Jr., Nicholas K. Sheridon, Edward A. Richley
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Patent number: 6507333Abstract: A display is provided with an insulative layer with electrical properties which have been selected so that the display can be addressed with a stylus and which minimizes the effects of stray triboelectrically generated charges. Also provided is a method of addressing such a display by depositing charges on a surface of the display, maintaining sufficient charge to effect an image change, and then removing the charges.Type: GrantFiled: November 24, 1999Date of Patent: January 14, 2003Assignee: Xerox CorporationInventors: James C. Mikkelsen, Jr., Nicholas K. Sheridon, Edward A. Richley
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Patent number: 6419982Abstract: A display comprised of a first component containing spheres encapsulated within a wax, and thereover and thereunder said component substrates.Type: GrantFiled: March 21, 2001Date of Patent: July 16, 2002Assignee: Xerox CorporationInventors: Guerino G. Sacripante, James C. Mikkelsen, Jr.
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Patent number: 6235395Abstract: A display comprised of a first component containing spheres encapsulated within a wax, and thereover and thereunder said component substrates.Type: GrantFiled: March 5, 1998Date of Patent: May 22, 2001Assignee: Xerox CorporationInventors: Guerino G. Sacripante, James C. Mikkelsen, Jr.
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Patent number: 6187211Abstract: A method of fabrication is provided for multi-step microlithographic structures including Fresnel lenses whereby the process includes the formation of intermediate etch stop layers that are embedded with the structure material. This is accomplished in one aspect of the invention by depositing Fresnel lens material using known techniques and the selectively altering the chemistry of the material being deposited to form the intermediate etch stop layers at suitable positions without interrupting the deposition process. In another aspect, etch stop layers are patterned on layers of the lens material and embedded between such layers. The structure, or lens, is then formed using masking, patterning and etching techniques.Type: GrantFiled: December 15, 1998Date of Patent: February 13, 2001Assignee: Xerox CorporationInventors: Donald L. Smith, James C. Mikkelsen, Jr., Babur B. Hadimioglu, Martin G. Lim
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Patent number: 6054071Abstract: Twisting balls (10) for an electric-paper display are formed from a polarizable material and encapsulated in a protective shell (12). The balls (10) are disposed between first and second electrodes (14, 16) which generate an electric field. The electric field polarizes each ball (10) transforming each into a dipole electret having a first and second charged poles. At least one colorant (20) is applied to each of the balls (10) to obtain multichromal balls such that the charged poles are distinct from each other. The polarized multichromal balls may then be used in fabricating an electric-paper display by encapsulating the balls (10) in an array such that each ball is capable of rotating in response to a selectively applied electric field.Type: GrantFiled: January 28, 1998Date of Patent: April 25, 2000Assignee: Xerox CorporationInventor: James C. Mikkelsen, Jr.
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Patent number: 5989629Abstract: A process for the preparation of bichromal spheres comprising (I) preparing monochromal spheres by the aggregation and coalescence of an emulsion resin with a first colorant and inorganic salt; (ii) contacting the resulting monchromal spheres with an oxidizing agent, followed by a polymerization with a vinyl monomer and a free radical initiator; (iii) forming a of the resulting monochromal spheres on a substrate; and (iv) subjecting the resulting monochromal spheres to a vapor thermal deposition with a second colorant dissimilar than the first colorant to thereby coat one hemisphere of each of said monochromal spheres thereby resulting in bichromal spheres with dissimilar colors.Type: GrantFiled: March 5, 1998Date of Patent: November 23, 1999Assignee: Xerox CorporationInventors: Guerino G. Sacripante, James C. Mikkelsen, Jr.
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Patent number: 5815306Abstract: A gyricon or rotating-particle display having an "eggcrate" substrate. The display includes a substrate having a cavity-containing matrix whose cavities are disposed substantially in a single layer and are arranged within the matrix substantially in a geometrically regular pattern, and a plurality of optically anisotropic particles disposed in the cavities in the substrate, with each cavity containing at most one of the optically anistropic particles. A rotatable disposition of each particle is achievable while the particle is thus disposed in the substrate; the particle, when in its rotatable disposition, is not attached to the substrate.Type: GrantFiled: December 24, 1996Date of Patent: September 29, 1998Assignee: Xerox CorporationInventors: Nicholas K. Sheridon, Linda T. Romano, James C. Mikkelsen, Jr., Edward A. Richley, Joseph M. Crowley
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Patent number: 5229595Abstract: A color scanner has a plurality of rows of photosensors. Spacers are formed between and around the rows, and a transparent cover sheet is sealed to the device, to form separate channels. An opening is provided in each otherwise sealed channel. The channels are filled with different colored media by evacuating the channels and letting the vacuum draw in different colored media such as liquids or gels.Type: GrantFiled: December 19, 1991Date of Patent: July 20, 1993Assignee: Xerox CorporationInventors: James C. Mikkelsen, Jr., William Turner
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Patent number: 5196652Abstract: A method for electrically connecting planar element substrates (12) to form an array (10) by forming conductive bridges (16) between metal pads (14) located on the surface of array elements (12). These bridges (16) are designed to transmit or receive visual, acoustical or other electromagnetic data and power. The conductive bridges (16) are formed to be nearly coplanar with the planar elements (12) and are made to connect the edges (14b) of pads (14) which are fused to the planar substrate (12). Metal wire (16a), solder (16b-c), a conductive polymer (16d), or a suspension of conductive particles in paste (16e) are used to bridge and electrically connect the pads (14) located on the array elements (12). The bridges (16) have a low profile, occupy a very small area and reduce the need for highly accurate alignment of adjacent substrates (12) within the tiled array (10) before electrical connections are formed.Type: GrantFiled: December 26, 1990Date of Patent: March 23, 1993Assignee: Xerox CorporationInventors: James C. Mikkelsen, Jr., William Meuli, Richard Bruce, Jackson Ho