Patents by Inventor James C. Miller
James C. Miller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12128026Abstract: This invention provides novel indole, indazole, benzimidazole, benzotriazole, indoline, quinolone, isoquinoline, and carbazole selective androgen receptor degrader (SARD) compounds, pharmaceutical compositions and uses thereof in treating hyperproliferations of the prostate including pre-malignancies and benign prostatic hyperplasia, prostate cancer, advanced prostate cancer, castration resistant prostate cancer, other AR-expressing cancers, androgenic alopecia or other hyper androgenic dermal diseases, Kennedy's disease, amyotrophic lateral sclerosis (ALS), abdominal aortic aneurysm (AAA), and uterine fibroids, and to methods for reducing the levels (through degradation) and/or activity (through inhibition) of any androgen receptor including androgen receptor-full length (AR-FL) including pathogenic and/or resistance mutations, AR-splice variants (AR-SV), and pathogenic polyglutamine (polyQ) polymorphisms of AR in a subject.Type: GrantFiled: March 14, 2022Date of Patent: October 29, 2024Assignees: University of Tennessee Research Foundation, Oncternal Therapeutics, Inc.Inventors: Ramesh Narayanan, Duane D. Miller, Thamarai Ponnusamy, Dong-Jin Hwang, Yali He, Jayaprakash Pagadala, Christopher C. Coss, James T. Dalton, Charles B. Duke
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Patent number: 12118240Abstract: An embodiment of an electronic apparatus may include one or more substrates, and logic coupled to the one or more substrates, the logic to maintain a respective lookup table for each of two or more persistent storage devices in a persistent memory outside of the two or more persistent storage devices with a first indirection granularity that is smaller than a second indirection granularity of each of the two or more persistent storage devices, buffer write requests to the two or more persistent storage devices in the persistent memory in accordance with the respective lookup tables, and perform a sequential write from the persistent memory to a particular device of the two or more persistent storage devices when a portion of the buffer that corresponds to the particular device has an amount of data to write that corresponds to the second indirection granularity. Other embodiments are disclosed and claimed.Type: GrantFiled: August 7, 2020Date of Patent: October 15, 2024Assignee: Intel CorporationInventors: Benjamin Walker, Sanjeev Trika, Kapil Karkra, James R. Harris, Steven C. Miller, Bishwajit Dutta
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Publication number: 20240292922Abstract: A safety helmet includes an outer shell configured for surrounding a head of a user, and an infrared reflective layer disposed in an interior of the outer shell. The infrared reflective layer is configured for reflecting at a least a portion of incident infrared radiation transmitted through the outer shell. The infrared reflective layer has infrared reflectivity of at least 40%. The safety helmet further may have an evaporative cooling pad positioned within a cavity defined by the inner surface of the outer shell. A method of manufacturing a safety helmet is also disclosed.Type: ApplicationFiled: May 14, 2024Publication date: September 5, 2024Inventors: Celeste L. Hort, Michael Goodspeed, Kevin R. Ketterer, Jefferson S. Mendenhall, Matthew C. Miller, James R. Tomlinson
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Publication number: 20240285596Abstract: Provided is a solid dispersion of (2R,3S,4S,5R)-4-[[3-(3,4-difluoro-2-methoxy-phenyl)-4,5-dimethyl-5-(trifluoromethyl) tetrahydrofuran-2-carbonyl]amino]pyridine-2-carboxamide (Compound 1), defined as described herein, or a pharmaceutically acceptable salt thereof and a tablet containing the solid dispersion for treating pain. Also disclosed herein is Compound 1 or a pharmaceutically acceptable salt thereof for use in a method of treating pain.Type: ApplicationFiled: June 3, 2022Publication date: August 29, 2024Applicant: VERTEX PHARMACEUTICALS INCORPORATEDInventors: Radhika KARKARE, Cathy CHU, Brenda CIRINCIONE, Darin J. CORRELL, Philip Kaj Harder DELFF, Kirk Raymond DINEHART, Paloma BENITO GALLO, Tanya Louise HAY, Licong JIANG, James B. JONES, Katie L. MCCARTY, Catherine P. METZLER, Jonathan M. MILLER, Mark C. PETERSON, Rahul ROOPWANI, John F. STAROPOLI
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Patent number: 10791691Abstract: A poppy straw of Papaver somniferum, wherein the poppy straw includes codeine constituting about 40% by weight or greater of an alkaloid combination.Type: GrantFiled: April 21, 2017Date of Patent: October 6, 2020Assignee: Tasmanian Alkaloids Pty. Ltd.Inventors: Anthony J. Fist, James A. C. Miller, Davina Gregory
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Publication number: 20170280647Abstract: A poppy straw of Papaver somniferum, wherein the poppy straw includes codeine constituting about 40% by weight or greater of an alkaloid combination.Type: ApplicationFiled: April 21, 2017Publication date: October 5, 2017Inventors: Anthony J. Fist, James A.C. Miller, Davina Gregory
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Patent number: 9648815Abstract: The present invention is directed to an improved poppy straw, concentrate of poppy straw and opium of Papaver somniferum for the production of codeine containing little or no oripavine, morphine or thebaine. The present invention also provides plants, stands and seeds of Papaver somniferum and methods for the production of codeine.Type: GrantFiled: March 15, 2013Date of Patent: May 16, 2017Assignee: Tasmanian Alkaloids Pty. Ltd.Inventors: Anthony J. Fist, James A. C. Miller, Davina Gregory
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Patent number: 8541647Abstract: The present invention is directed to an improved poppy straw, concentrate of poppy straw and opium of Papaver somniferum for the production of codeine containing little or no oripavine, morphine or thebaine. The present invention also provides plants, stands and seeds of Papaver somniferum and methods for the production of codeine.Type: GrantFiled: May 22, 2009Date of Patent: September 24, 2013Assignee: Tasmania Alkaloids Pty, Ltd.Inventors: Anthony J. Fist, James A. C. Miller, Davina Gregory
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Patent number: 8516859Abstract: An automatic washing machine having a tub defining an interior, a sump in fluid communication with the interior of the tub, a wash basket located within the interior of the tub and defining a laundry treating space, and a foreign object trap located in a portion of the wash basket that defines a foreign object passageway for retaining foreign objects.Type: GrantFiled: December 21, 2009Date of Patent: August 27, 2013Assignee: Whirlpool CorporationInventors: Lauren M. Lalonde, Donald R. Miller, James C. Miller, Brenner M. Sharp, Jon D. Strait, Dean L. Tietz, Nyik Siong Wong
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Publication number: 20120311757Abstract: The Lower Back Spinal Support is a back support device worn by people laying down all types of flooring to support your upper torso, consisting of a wearable aluminum alloy breast plate padded in a form cushion, with an aluminum cylindrical telescopic swivel leg for height adjustment (which locks into place) and adjustable neck and back straps.Type: ApplicationFiled: May 10, 2012Publication date: December 13, 2012Inventor: James C. Miller
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Publication number: 20120267912Abstract: A tarp bar may be an alignment, reinforcement, and furling control member, without adding substantial weight or complexity to a rolling tarp system. The tarp bar is not motorized or otherwise powered, and is preferably attached only to the tarp material, a significant distance from the drive bar and parallel to the length of the tarp and the bed/trailer. The tarp bar is recessed or otherwise-concave along its length to allow cradling of, and hence parallel orientation of, an already-rolled portion of the tarp. The tarp bar is preferably broader than said already-rolled portion and the combination of the already-rolled portion received in the tarp bar is a non-cylindrical unit. Subsequent rolling-up of the tarp tends to occur in a cam-like action that maintains more consistent tension all along the length of the tarp, to form a tighter and more even roll.Type: ApplicationFiled: April 24, 2012Publication date: October 25, 2012Applicant: TRINITY TRAILER MFG., INC.Inventors: JAMES C. MILLER, MICHAEL R. HUNTER
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Patent number: 8162377Abstract: A tarp bar may be an alignment member, a reinforcement member, and a furling control member, without adding substantial weight or complexity to a rolling tarp system. The tarp bar is fixed to the tarp a significant distance from the drive bar and is not motorized or otherwise powered, and is preferably attached only to the tarp material, parallel to the length of the tarp and the bed/trailer. The tarp bar is recessed or otherwise-concave along its length to allow cradling of, and hence parallel orientation of, an already-rolled portion of the tarp. The tarp bar is preferably broader than said already-rolled portion, so that two opposing edges of the tarp bar extend out beyond the diameter of the already-rolled portion so that the combination of the already-rolled portion received in the tarp bar is a non-cylindrical unit.Type: GrantFiled: August 6, 2009Date of Patent: April 24, 2012Assignee: Trinity Trailer Mfg., Inc.Inventors: James C. Miller, Michael R. Hunter
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Publication number: 20110146354Abstract: An automatic washing machine having a foreign object trap located in a portion of a wash basket defines a foreign object passageway for retaining foreign objects.Type: ApplicationFiled: December 21, 2009Publication date: June 23, 2011Applicant: WHIRLPOOL CORPORATIONInventors: Lauren M. Lalonde, Donald R. Miller, James C. Miller, Brenner M. Sharp, Jon D. Strait, Dean L. Tietz, Nyik Siong Wong
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Publication number: 20100234600Abstract: The present invention is directed to an improved poppy straw, concentrate of poppy straw and opium of Papaver somniferum for the production of codeine containing little or no oripavine, morphine or thebaine. The present invention also provides plants, stands and seeds of Papaver somniferum and methods for the production of codeine.Type: ApplicationFiled: May 22, 2009Publication date: September 16, 2010Inventors: Anthony J. Fist, James A.C. Miller, Davina Gregory
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Publication number: 20100032978Abstract: A tarp bar may be an alignment member, a reinforcement member, and a furling control member, without adding substantial weight or complexity to a rolling tarp system. The tarp bar is fixed to the tarp a significant distance from the drive bar and is not motorized or otherwise powered, and is preferably attached only to the tarp material, parallel to the length of the tarp and the bed/trailer. The tarp bar is recessed or otherwise-concave along its length to allow cradling of, and hence parallel orientation of, an already-rolled portion of the tarp. The tarp bar is preferably broader than said already-rolled portion, so that two opposing edges of the tarp bar extend out beyond the diameter of the already-rolled portion so that the combination of the already-rolled portion received in the tarp bar is a non-cylindrical unit.Type: ApplicationFiled: August 6, 2009Publication date: February 11, 2010Applicant: TRINITY TRAILER MFG., INCInventors: JAMES C. MILLER, MICHAEL R. HUNTER
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Patent number: 7597191Abstract: A self-unloading bed includes a conveyor with chain bars that are strong, light-weight and non-damaging to the floor upon which the conveyor slides. The preferred chain bar is an elongated bar with two legs, each of said two legs having a foot. The feet extend away from the leading (unloading) direction, the transition from leg to foot being formed by smooth bends, so that no sharp edges exist that would gouge into the floor as the chain bar moves across the floor. The preferred chain bar, made of a single metal bar with four longitudinal bends, is extremely strong for its weight, and it unlikely to bend or gouge into the floor during use.Type: GrantFiled: May 2, 2006Date of Patent: October 6, 2009Assignee: Trinity Trailer Mfg., Inc.Inventors: Peter L. Eisenman, James C. Miller, Ren Barry Bai
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Patent number: 6604536Abstract: An apparatus and process for removing and recovering contaminants from a pipeline while containing and preventing the contaminants from spilling or leaking into the environment during said removal comprising. Specifically, the apparatus and method effectively and safely remove PCBs from a gas transmission pipeline. The apparatus and method implements a unique coupling system the prevents dangerous contaminants from escaping into the environment. Furthermore, the apparatus and method implements and system for recycling cleaning solution for continuous treatment of the pipeline.Type: GrantFiled: August 2, 1999Date of Patent: August 12, 2003Assignee: Miller Environmental Group, Inc.Inventors: Jim Davey, James C. Miller
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Patent number: 6132144Abstract: A passive anchor latching mechanism which allows its user to attach a moog line to an anchor without using a secondary mechanism such as a remotely operated vehicle to attach the cable or anchor wire to the anchor. The passive anchor latching mechanism comprises three elements: (1) a latch ring which may have a tether line removably coupled thereto; (2) an anchor post extending vertically upward from the top of the anchor; and (3) a crown line attached to the anchor and buoyed at the water's surface. The latch ring consist of a tail which attaches to the mooring line and a ring which slides downward along the crown line. The anchor post has an anchor collar coupled thereto which forms an annulus groove with the anchor post. The annulus grove latches the ring of the latch ring to the anchor post while the tail of the latch ring prevents the ring from detaching from the anchor post and riding backward up the anchor post once the latch ring is latched.Type: GrantFiled: December 17, 1998Date of Patent: October 17, 2000Assignee: The United States of America as represented by the Secretary of the NavyInventors: Robert F. Zueck, James C. Miller, Robert J. Taylor, Karen Miller, David R. Shields, Richard C. Lundberg
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Patent number: 6034616Abstract: An electronic combination lock includes a combination lock having a dial with no markings thereon. Rotation of the dial drives a generator which produces electrical pulses. The voltage pulses serves as a power source for the electronics of the lock. The lock also includes a security feature to disable the lock if the combination dial is stopped between dial rotations for a period of time which indicates dialing by an automatic dialer.Type: GrantFiled: July 6, 1998Date of Patent: March 7, 2000Assignee: C&M Technology, Inc.Inventors: Michael P. Harvey, James C. Miller, Gerald L. Dawson, Daniel L. Thompson
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Patent number: 5777559Abstract: An electronic combination lock includes a combination lock having a dial with no markings thereon. Rotation of the dial drives a generator which produces electrical pulses. The voltage pulses serves as a power source for the electronics of the lock. The lock also includes a security feature to disable the lock if the combination dial is stopped between dial rotations for a period of time which indicates dialing by an automatic dialer.Type: GrantFiled: August 11, 1997Date of Patent: July 7, 1998Assignee: C & M Technology, Inc.Inventors: Gerald Lee Dawson, Daniel Lee Thompson, Michael P. Harvey, James C. Miller