Abstract: The present invention relates to compositions and methods for inducing an adaptive immune response against Hepatitis C virus (HCV) in a subject. In some embodiments, the present invention provides a composition comprising a nucleoside-modified nucleic acid molecule encoding a HCV antigen, adjuvant, or a combination thereof. For example, in some embodiments, the composition comprises a vaccine comprising a nucleoside-modified nucleic acid molecule encoding a HCV antigen, adjuvant, or a combination thereof.

Abstract: A composition comprising at least one fuel that is a diesel fuel, a biodiesel fuel, or combinations thereof and less than 100 ppm, less than 50 ppm (or less than 25 ppm, less than 10 ppm, 1 to 7 ppm, or 5 to 7 ppm) of an alkylene-coupled C10 to C60 (or C10 to C40, C14 to C32 or C24 to C28) alkylphenol; 25 to 500 ppm (or 50 to 500 ppm, or 150 to 450 ppm or 250 to 450 ppm, or 250 to 400 ppm) of a terpolymer; and 5 to 90 ppm, (or 10 to 70 ppm, to 60 ppm, or 10 to 55 ppm) of hydrocarbyl-substituted amine detergent having at least one tertiary amino group.

Abstract: The invention relates to quaternary ammonium amide and/or ester salts and their use as additives, including their use in fuels, such as diesel fuel. The invention particularly relates to the use of quaternary ammonium amide and/or ester salts as detergents in diesel fuels.

Abstract: The invention relates to quaternary ammonium amide and/or ester salts and their use as additives, including their use in fuels, such as diesel fuel. The invention particularly relates to the use of quaternary ammonium amide and/or ester salts as detergents in diesel fuels.

Abstract: A heat exchanger for an engine includes: an inlet; an outlet; a radiator spanning the inlet and the outlet and in fluid communication with both the inlet and the outlet; and a bypass element spanning the inlet and the outlet and in fluid communication with both the inlet and the outlet and in parallel fluid communication with the radiator, the bypass element including a control mechanism, the control mechanism including a bypass valve and a control cylinder connected to the bypass valve for operating the bypass valve, the control cylinder including a pneumatic ram cylinder in communication with a turbocharger outlet of the engine.

Abstract: In certain embodiments, a pile bridge assembly includes first and second pile brackets for rigid mounting onto first and second piles of a pier; a cap bracket sub-assembly for rigid mounting onto a beam of the pier supported by the first and second piles; a first compression arm rotatably connected (i) at a first end to the first pile bracket and (ii) at a second end to the cap bracket sub-assembly; and a second compression arm rotatably connected (i) at a first end to the second pile bracket and (ii) at a second end to the cap bracket sub-assembly. The pile bridge assembly restores the load capacity of damaged or degraded piers. The cap bracket sub-assembly can include first and second cap brackets, and the pile bridge assembly can further include one or more tension-managing straps.

Abstract: In certain embodiments, a cap repair assembly includes first and second pile brackets for rigid mounting onto first and second piles of a pier: a cap beam for rigid mounting onto super-structure of the pier; first and second cap beam plates for rigid mounting onto the cap beam at different ends of the cap beam; first and second compression arms rotatably connected (i) at first ends to the first and second pile brackets and (ii) at second ends to the first and second cap beam plates. The cap repair assembly restores the load capacity of damaged or degraded piers. The cap repair assembly can further include one or more steel banding straps.

Abstract: In certain embodiments, a pile bridge assembly includes first and second pile brackets for rigid mounting onto first and second piles of a pier; a cap bracket sub-assembly for rigid mounting onto a beam of the pier supported by the first and second piles; a first compression arm rotatably connected (i) at a first end to the first pile bracket and (ii) at a second end to the cap bracket sub-assembly; and a second compression arm rotatably connected (i) at a first end to the second pile bracket and (ii) at a second end to the cap bracket sub-assembly. The pile bridge assembly restores the load capacity of damaged or degraded piers. The cap bracket sub-assembly can include first and second cap brackets, and the pile bridge assembly can further include one or more tension-managing straps.

Abstract: The invention relates to quaternary ammonium amide and/or ester salts and their use as additives, including their use in fuels, such as diesel fuel. The invention particularly relates to the use of quaternary ammonium amide and/or ester salts as detergents in diesel fuels.

Abstract: In certain embodiments, a cap repair assembly includes first and second pile brackets for rigid mounting onto first and second piles of a pier; a cap beam for rigid mounting onto super-structure of the pier; first and second cap beam plates for rigid mounting onto the cap beam at different ends of the cap beam; first and second compression arms rotatably connected (i) at first ends to the first and second pile brackets and (ii) at second ends to the first and second cap beam plates. The cap repair assembly restores the load capacity of damaged or degraded piers. The cap repair assembly can further include one or more steel banding straps.

Abstract: A vehicle barrier apparatus includes a horizontal barrier component, a vertical barrier component, at least one rigid stabilizer beam having two end surfaces and at least one elongated side surface. One end of the stabilizer beam is affixed to the vertical barrier component. The elongated side surface of the stabilizer beam is affixed to the horizontal barrier component to prevent rotational movement of the vertical barrier component. A lower surface of the horizontal barrier component is a friction-enhanced surface which creates a sliding friction interface upon contact of a moving vehicle with the vertical barrier component.

Abstract: The invention relates to quaternary ammonium amide and/or ester salts and their use as additives, including their use in fuels, such as diesel fuel. The invention particularly relates to the use of quaternary ammonium amide and/or ester salts as detergents in diesel fuels.

Abstract: The invention relates to quaternary ammonium amide and/or ester salts and their use as additives, including their use in fuels, such as diesel fuel. The invention particularly relates to the use of quaternary ammonium amide and/or ester salts as detergents in diesel fuels.

Abstract: A vehicle barrier apparatus includes a horizontal barrier component, a vertical barrier component, at least one rigid stabilizer beam having two end surfaces and at least one elongated side surface. One end of the stabilizer beam is affixed to the vertical barrier component. The elongated side surface of the stabilizer beam is affixed to the horizontal barrier component to prevent rotational movement of the vertical barrier component. A lower surface of the horizontal barrier component is a friction-enhanced surface which creates a sliding friction interface upon contact of a moving vehicle with the vertical barrier component.

Abstract: A heat exchanger for an engine includes: an inlet; an outlet; a radiator spanning the inlet and the outlet and in fluid communication with both the inlet and the outlet; and a bypass element spanning the inlet and the outlet and in fluid communication with both the inlet and the outlet and in parallel fluid communication with the radiator, the bypass element including a control mechanism, the control mechanism including a bypass valve and a control cylinder connected to the bypass valve for operating the bypass valve, the control cylinder including a pneumatic ram cylinder in communication with a turbocharger outlet of the engine.

Abstract: A system, apparatus and method for maintaining power in an internal combustion typically turbocharged aircraft engine is disclosed. During descent, air pressure and temperature in the manifold can fall to dangerous levels. This is because engine power is low and likewise turbocharger output is also low. The system and method provide for a bypass of the heat radiator during low power periods, or with low ambient temperature or both. A parameter is measured, often manifold pressure or temperature and the degree of bypass is adjusted commensurately.

Abstract: The invention relates to quaternary ammonium amide and/or ester salts and their use as additives, including their use in fuels, such as diesel fuel. The invention particularly relates to the use of quaternary ammonium amide and/or ester salts as detergents in diesel fuels.

Abstract: The invention relates to quaternary ammonium amide and/or ester salts and their use as additives, including their use in fuels, such as diesel fuel. The invention particularly relates to the use of quaternary ammonium amide and/or ester salts as detergents in diesel fuels.

Abstract: The present invention provides a nitrogen-free fuel detergent additive, fuel additive compositions containing the same, and fuel compositions containing the same, for use in internal combustion engines, where the additive is the reaction product of (i) hydrocarbyl phenol, cresol or similar material and (ii) a aldehyde, in the presence of an optional catalyst, wherein the additive provides acceptable engine deposit control that is comparable and/or better than the deposit control provided by nitrogen-containing fuel additives.

Abstract: The invention relates to quaternary ammonium amide and/or ester salts and their use as additives, including their use in fuels, such as diesel fuel. The invention particularly relates to the use of quaternary ammonium amide and/or ester salts as detergents in diesel fuels.