Patents by Inventor James C. Stolzenbach

James C. Stolzenbach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for improving lipid profiles using atrasentan
    Patent number: 9855245
    Abstract: The present disclosure is directed to methods for reducing cardiovascular risk in a human subject by administering atrasentan, or a pharmaceutically acceptable salt thereof, in an amount sufficient to effect a reduction of about 5% or more in one or both of (a) total serum cholesterol, relative to the subject's baseline total serum cholesterol, and (b) serum LDL cholesterol, relative to the subject's baseline serum LDL cholesterol.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: January 2, 2018
    Assignee: AbbVie Inc.
    Inventors: Blas Coll Crespo, Dennis Andress, John J. Brennan, James C. Stolzenbach
  • METHODS FOR IMPROVING LIPID PROFILES USING ATRASENTAN
    Publication number: 20160074363
    Abstract: The present disclosure is directed to methods for reducing cardiovascular risk in a human subject by administering atrasentan, or a pharmaceutically acceptable salt thereof, in an amount sufficient to effect a reduction of about 5% or more in one or both of (a) total serum cholesterol, relative to the subject's baseline total serum cholesterol, and (b) serum LDL cholesterol, relative to the subject's baseline serum LDL cholesterol.
    Type: Application
    Filed: April 30, 2014
    Publication date: March 17, 2016
    Applicant: Abbvie Inc.
    Inventors: Blas COLL CRESPO, Dennis ANDRESS, Peter J. BRENNAN, James C. STOLZENBACH
  • Self-emulsifying drug delivery system
    Patent number: 7226932
    Abstract: Oral pharmaceutical formulation which improves the bioavailability of pharmaceuticals which are substantially water and oil insoluble is disclosed. In addition to the pharmaceutical, the formulation includes an emulsifier, an oil and an solubilizer. Alternatively, the formulation includes an aqueous solution of solubilizer.
    Type: Grant
    Filed: April 29, 2003
    Date of Patent: June 5, 2007
    Assignee: G.D. Searle LLC
    Inventors: Rajeev Gokhale, Martin J. Griffin, James E. Truelove, James C. Stolzenbach, Aziz Karim, Ajit K. Roy
  • Self-emulsifying drug delivery system
    Publication number: 20040048934
    Abstract: Oral pharmaceutical formulation which improves the bioavailability of pharmaceuticals which are substantially water and oil insoluble is disclosed. In addition to the pharmaceutical, the formulation includes an emulsifier, an oil and an solubilizer. Alternatively, the formulation includes an aqueous solution of solubilizer.
    Type: Application
    Filed: April 29, 2003
    Publication date: March 11, 2004
    Applicant: G.D. Searle & Co.
    Inventors: Rajeev Gokhale, Martin J. Griffin, James E. Truelove, James C. Stolzenbach, Aziz Karim, Ajit K. Roy
  • Retroviral protease inhibitors and combinations thereof
    Patent number: 5750648
    Abstract: The present invention is directed to the preparation and use of retroviral protease inhibitors and combinations of retroviral protease inhibitors which are effective in preventing the replication of mammalian retroviruses, such as human immunodeficiency virus (HIV).
    Type: Grant
    Filed: June 3, 1994
    Date of Patent: May 12, 1998
    Assignee: G.D. Searle & Co.
    Inventors: Min S. Chang, Daniel P. Getman, Richard A. Mueller, James C. Ottinger, James C. Stolzenbach, John J. Talley, Michael L. Vazquez, Gary A. Decrescenzo