Patents by Inventor James C. Sutton

James C. Sutton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
    Patent number: 6995183
    Abstract: Compounds are provided having the formula (I) wherein: n is 0, 1 or 2; m is 0, 1 or 2; the sum of n+m less then or equal to 2; the dashed bonds forming a cyclopropyl ring can only be present when Y is CH; X is H or CN; Y is CH, CH2, CHF, CF2, O, S, SO, or SO2; and A is adamantyl. Further provided are methods of using such compounds for the treatment of diabetes and related diseases, and to pharmaceutical compositions containing such compounds.
    Type: Grant
    Filed: July 27, 2004
    Date of Patent: February 7, 2006
    Assignee: Bristol Myers Squibb Company
    Inventors: Lawrence G. Hamann, Ashish Khanna, Mark S. Kirby, David R. Magnin, Ligaya M. Simpkins, James C. Sutton, Jeffrey Robl
  • Bicyclic modulators of androgen receptor function
    Publication number: 20040181064
    Abstract: The invention provides compounds according to formula I 1
    Type: Application
    Filed: February 17, 2004
    Publication date: September 16, 2004
    Inventors: Chong-Qing Sun, Lawrence Hamann, David Augeri, Yingzhi Bi, Jeffrey Robl, Yan-Ting Huang, Tammy Wang, Alexandra Holubec, Ligaya Simpkins, James C. Sutton, James J. Li
  • Beta lactam compounds and their use as inhibitors of tryptase
    Publication number: 20040147502
    Abstract: Beta lactam compounds are provided which have the structure 1
    Type: Application
    Filed: December 4, 2003
    Publication date: July 29, 2004
    Inventors: Gregory S. Bisacchi, James C. Sutton, William A. Slusarchyk, Uwe Treuner, Guohua Zhao
  • Acid derivatives useful as serine protease inhibitors
    Patent number: 6713467
    Abstract: Compounds of formula I and II, or pharmaceutically-acceptable salts thereof, are useful as inhibitors of Factor VIIa, Factor IXa, Factor Xa, Factor FXIa, tryptase, and urokinase, wherein ring B is phenyl or pyridyl, L is a linker, and R1-R27, W, Z1, and Z2 are as defined in the specification.
    Type: Grant
    Filed: November 7, 2001
    Date of Patent: March 30, 2004
    Assignee: Bristol-Myers Squibb Company
    Inventors: Gregory S. Bisacchi, James C. Sutton, Shung C. Wu
  • Acid derivatives useful as serine protease inhibitors
    Patent number: 6642252
    Abstract: Compounds having the formula (I), are useful as serine protease inhibitors, more particularly inhibitors of Factors VIIa, IXa, Xa, and/or XIa, wherein ring B is phenyl or pyridyl, W is preferably C(═O)NR4R5, L is a linker group, X2 comprises nitrogen or carbon, Z is an optionally-substituted monocyclic or bicyclic ring system, and R1, R2, R3, R4, R5 and R6 are as defined in the specification.
    Type: Grant
    Filed: November 7, 2001
    Date of Patent: November 4, 2003
    Assignee: Bristol-Myers Squibb Company
    Inventors: Gregory S. Bisacchi, James C. Sutton, William A. Slusarchyk, Uwe D. Treuner, Guohua Zhao, Daniel L. Cheney, Yan Shi, Shung C. Wu
  • Acid derivatives useful as serine protease inhibitors
    Publication number: 20030166685
    Abstract: Compounds having the formula (I), 1
    Type: Application
    Filed: November 7, 2001
    Publication date: September 4, 2003
    Inventors: Gregory S. Bisacchi, James C. Sutton, William A. Slusarchyk, Uwe D. Treuner, Guohua Zhao, Daniel L. Cheney, Yan Shi, Shung C. Wu
  • Acid derivatives useful as serine protease inhibitors
    Publication number: 20020151545
    Abstract: Compounds of formula I and II, 1
    Type: Application
    Filed: November 7, 2001
    Publication date: October 17, 2002
    Inventors: Gregory S. Bisacchi, James C. Sutton, Shung C. Wu
  • Lactam compounds and their use as inhibitors of serine proteases and method
    Patent number: 6344450
    Abstract: Lactam inhibitors are provided which have the structure X is wherein Y is O or S and R4 is  R7O— or R8 and R1, R2, R3, R5, R6, R7, and R8, are as defined herein. These compounds are inhibitors of Factor Xa and thus are useful as anticoagulants, and are inhibitors of tryptase and thus are useful in treating asthma. Methods for treating cardiovascular diseases associated with thromboses and for treating asthma and related diseases are also provided.
    Type: Grant
    Filed: August 7, 2000
    Date of Patent: February 5, 2002
    Assignee: Bristol-Myers Squibb Company
    Inventors: Gregory S. Bisacchi, Steven M. Seiler, R. Michael Lawrence, James C. Sutton, Jr., William A. Slusarchyk, Guohua Zhao
  • Beta lactam compounds and their use as inhibitors of tryptase
    Patent number: 6335324
    Abstract: Compounds of the formulas: are disclosed. These compounds inhibit tryptase as well as other enzyme systems or are selective tryptase inhibitors and are useful as antiinflammatory agents particularly in the treatment of chronic asthma.
    Type: Grant
    Filed: December 13, 1999
    Date of Patent: January 1, 2002
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Gregory S. Bisacchi, William A. Slusarchyk, Uwe Treuner, James C. Sutton, Robert Zahler, Steven Seiler, David R. Kronenthal, Michael E. Randazzo, Mark D. Schwinden, Zhongmin Xu, Zhongping Shi
  • Dynamic rotating ballistic shield
    Patent number: 5447091
    Abstract: A dynamic rotating ballistic shield for protecting an enclosed viewing dee. A rotating inner armor sleeve around the device includes a sleeve opening. When the sleeve aligned with a cap opening of an outer armor cap which concentrically surrounds the rotatable inner armor sleeve, a substantially unobstructed field-of-view for the objective window is obtained, with substantial ballistic shield protection.
    Type: Grant
    Filed: September 29, 1994
    Date of Patent: September 5, 1995
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventor: James C. Sutton
  • Dynamic rotating ballistic shield
    Patent number: 5375505
    Abstract: A dynamic rotating ballistic shield for protecting an enclosed viewing dee. A rotating inner armor sleeve around the device includes a sleeve opening. When the sleeve aligned with a cap opening of an outer armor cap which concentrically surrounds the rotatable inner armor sleeve, a substantially unobstructed field-of-view for the objective window is obtained, with substantial ballistic shield protection.
    Type: Grant
    Filed: February 25, 1993
    Date of Patent: December 27, 1994
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventor: James C. Sutton