Abstract: Provided herein are agonistic antibodies, or antigen binding portions thereof, that bind to human CD40 and comprise improved heavy and light chain variable regions that impart improved yield and reduced aggregation. The invention also provides methods of treatment of cancer or chronic infection by administering the antibodies of the invention to a subject in need thereof.

Abstract: A crash-ready, portable, item compartmentalization device may include a shell which includes a first half shell and a second half shell. The first half shell and the second half shell may have substantially similar dimensions and define an interior space and an exterior space. One or more pouches may be removably coupled to the shell in the interior space. The crash-ready, portable, item compartmentalization device may be relocated throughout the interior of an emergency vehicle when used with an equipment mounting system or taken to the field for use away from the emergency vehicle. The individual pouches may also be removed and replaced with stocked pouches to replenish the crash-ready, portable, item compartmentalization device.

Abstract: An equipment mounting system may include a quick mount track having a backing plate with a center slot, a first outer slot, and a second outer slot, the first outer slot and the second outer slot comprise a plurality of diamond contour target regions, and a plurality of locking pin apertures along the center slot in the backing plate, the locking pin apertures are in horizontal alignment with the plurality of diamond contoured target regions. The equipment mounting system also may include a mount removably coupled to the quick mount track wherein the plurality of diamond contour target regions allow for a round head of a t-shaped stud of the mount to engage the first outer slot and the second outer slot at an angle to the backing plate.

Abstract: A crash-ready, portable, item compartmentalization device may include a shell which includes a first half shell and a second half shell. The first half shell and the second half shell may have substantially similar dimensions and define an interior space and an exterior space. One or more pouches may be removably coupled to the shell in the interior space. The crash-ready, portable, item compartmentalization device may be relocated throughout the interior of an emergency vehicle when used with an equipment mounting system or taken to the field for use away from the emergency vehicle. The individual pouches may also be removed and replaced with stocked pouches to replenish the crash-ready, portable, item compartmentalization device.

Abstract: A crash-ready, portable, item compartmentalization device may include a shell which includes a first half shell and a second half shell. The first half shell and the second half shell may have substantially similar dimensions and define an interior space and an exterior space. One or more pouches may be removably coupled to the shell in the interior space. The crash-ready, portable, item compartmentalization device may be relocated throughout the interior of an emergency vehicle when used with an equipment mounting system or taken to the field for use away from the emergency vehicle. The individual pouches may also be removed and replaced with stocked pouches to replenish the crash-ready, portable, item compartmentalization device.

Abstract: Various technologies for mitigating distortion in coherent image products generated from SAR data are described herein. Synthetic aperture radar (SAR) datasets generated based upon SAR returns from first and second passes of a SAR platform over a scene are received. The SAR datasets can be co-notched at matching sample indices to improve coherence of SAR images generated from the datasets. Windowed SAR data is generated by applying independent windows to subsets of each of the datasets to reduce sidelobe levels of their image impulse responses. Coherent image products are generated based upon the windowed SAR data, wherein an image quality of the coherent image products is improved as compared to coherent image products generated based upon the SAR datasets.

Abstract: A track mounting system including a mount with a mounting plate with a back surface and a front surface, the back surface is opposite the front surface and at least one mounting stud coupled to the back surface of the mounting plate, each mounting stud includes a stem portion that extends outwardly from the back surface and an enlarged head portion disposed at a distal end of stem portion. The mount also includes a release mechanism coupled to the front surface to release the mount from a track. The track mounting system also includes an adaptor coupled to the front surface of the mounting plate wherein the adaptor releasably couples with an equipment interface of a piece of equipment.

Abstract: A crash-ready, portable, item compartmentalization device may include a shell which includes a first half shell and a second half shell. The first half shell and the second half shell may have substantially similar dimensions and define an interior space and an exterior space. One or more pouches may be removably coupled to the shell in the interior space. The crash-ready, portable, item compartmentalization device may be relocated throughout the interior of an emergency vehicle when used with an equipment mounting system or taken to the field for use away from the emergency vehicle. The individual pouches may also be removed and replaced with stocked pouches to replenish the crash-ready, portable, item compartmentalization device.

Abstract: A crash-ready, portable, item compartmentalization device (100) includes a shell (300) which includes a first half shell (105) and a second half shell (205). The first half shell (105) and the second half shell (205) have substantially similar dimensions and define an interior space (710) and an exterior space (715). One or more pouches (900) are removably coupled to the shell (300) in the interior space (710). The crash-ready, portable, item compartmentalization device (100) may be relocated throughout the interior of an emergency vehicle when used with an equipment mounting system or taken to the field for use away from the emergency vehicle. The individual pouches (900) may also be removed and replaced with stocked pouches to replenish the crash-ready, portable, item compartmentalization device (100).

Abstract: A crash-ready, portable, item compartmentalization device may include a shell which includes a first half shell and a second half shell. The first half shell and the second half shell may have substantially similar dimensions and define an interior space and an exterior space. One or more pouches may be removably coupled to the shell in the interior space. The crash-ready, portable, item compartmentalization device may be relocated throughout the interior of an emergency vehicle when used with an equipment mounting system or taken to the field for use away from the emergency vehicle. The individual pouches may also be removed and replaced with stocked pouches to replenish the crash-ready, portable, item compartmentalization device.

Abstract: An equipment mounting system includes a quick mount track (11) with tapered edges (3611, 3612) couple to a surface or structure. The quick mount track includes a backing plate (15), one or more mounting points positioned such that any forces exerted on a mount (50) coupled to the quick mount track is transferred directly through the quick mount track to the one or more mounting points. The quick mount track also includes a flush mounting surface (3610) that creates and maintains a seal between the quick mount track and the surface, and a chase (3605) is disposed in the quick mount track and defined by the flush mounting surface. A plurality of diamond contoured target regions (13) and a plurality of half diamond contour regions in the backing plate aid in coupling the mount to the quick mount track.

Abstract: A track mounting system including a mount with a mounting plate with a back surface and a front surface, the back surface is opposite the front surface and at least one mounting stud coupled to the back surface of the mounting plate, each mounting stud includes a stem portion that extends outwardly from the back surface and an enlarged head portion disposed at a distal end of stem portion. The mount also includes a release mechanism coupled to the front surface to release the mount from a track. The track mounting system also includes an adaptor coupled to the front surface of the mounting plate wherein the adaptor releasably couples with an equipment interface of a piece of equipment.

Abstract: A track mounting system including a mount with a mounting plate with a back surface and a front surface, the back surface is opposite the front surface and at least one mounting stud coupled to the back surface of the mounting plate, each mounting stud includes a stem portion that extends outwardly from the back surface and an enlarged head portion disposed at a distal end of stem portion. The mount also includes a release mechanism coupled to the front surface to release the mount from a track. The track mounting system also includes an adaptor coupled to the front surface of the mounting plate wherein the adaptor releasably couples with an equipment interface of a piece of equipment.

Abstract: An equipment mounting system may include a quick mount track having a backing plate with a center slot, a first outer slot, and a second outer slot, the first outer slot and the second outer slot comprise a plurality of diamond contour target regions, and a plurality of locking pin apertures along the center slot in the backing plate, the locking pin apertures are in horizontal alignment with the plurality of diamond contoured target regions. The equipment mounting system also may include a mount removably coupled to the quick mount track wherein the plurality of diamond contour target regions allow for a round head of a t-shaped stud of the mount to engage the first outer slot and the second outer slot at an angle to the backing plate.

Abstract: An equipment mounting system may include a quick mount track having a backing plate with a center slot, a first outer slot, and a second outer slot, the first outer slot and the second outer slot comprise a plurality of diamond contour target regions, and a plurality of locking pin apertures along the center slot in the backing plate, the locking pin apertures are in horizontal alignment with the plurality of diamond contoured target regions. The equipment mounting system also may include a mount removably coupled to the quick mount track wherein the plurality of diamond contour target regions allow for a round head of a t-shaped stud of the mount to engage the first outer slot and the second outer slot at an angle to the backing plate.

Abstract: An equipment mounting system includes a quick mount track (11) with tapered edges (3611, 3612) couple to a surface or structure. The quick mount track includes a backing plate (15), one or more mounting points positioned such that any forces exerted on a mount (50) coupled to the quick mount track is transferred directly through the quick mount track to the one or more mounting points. The quick mount track also includes a flush mounting surface (3610) that creates and maintains a seal between the quick mount track and the surface, and a chase (3605) is disposed in the quick mount track and defined by the flush mounting surface. A plurality of diamond contoured target regions (13) and a plurality of half diamond contour regions in the backing plate aid in coupling the mount to the quick mount track.

Abstract: A crash-ready, portable, item compartmentalization device (100) includes a shell (300) which includes a first half shell (105) and a second half shell (205). The first half shell (105) and the second half shell (205) have substantially similar dimensions and define an interior space (710) and an exterior space (715). One or more pouches (900) are removably coupled to the shell (300) in the interior space (710). The crash-ready, portable, item compartmentalization device (100) may be relocated throughout the interior of an emergency vehicle when used with an equipment mounting system or taken to the field for use away from the emergency vehicle. The individual pouches (900) may also be removed and replaced with stocked pouches to replenish the crash-ready, portable, item compartmentalization device (100).