Abstract: Described herein are techniques for determining motion characteristics (e.g., position, velocity, acceleration, etc.) of one or more trains traveling along a train track, such that train control systems may have the information needed to safely operate the trains at higher speeds and with shorter separation between trains. In accordance with various embodiments, systems and methods described herein may be configured to determine a position, velocity, and/or acceleration of a train traveling along a train track. In some embodiments, the motion characteristics may be determined one or more radio frequency antennas onboard the train, such as in communication with one or more anchor nodes positioned adjacent the train track. Alternatively or additionally, in some embodiments motion characteristics may be determined using one or more one or more inertial measurement units (IMUs) onboard the train.

Abstract: Systems and methods for facilitating interactions between a medical device (e.g., an imaging device, a surgical tool, a robotic arm, etc.) and a patient using radio frequency (RF) co-localization are provided. The systems include a radio-frequency (RF) interrogator system, one or more first RF target devices for coupling to a patient support for supporting a patient with respect to whom a medical device is to perform a task, and one or more second RF target devices for coupling to the medical device. A controller determines a position of the patient support within an RF interrogator system reference frame, a first position of the medical device within the RF interrogator system reference frame, a transformation between the RF interrogator system reference frame and a patient support reference frame, and a second position of the medical device within the patient support reference frame.

Abstract: An insert for an EPR probehead is disclosed. The insert comprises a directional coupler and an amplifier. The directional coupler receives microwave power from a source at a first port and transfers a portion of the received microwave power to a second port for transmission to a sample space. The directional coupler is also arranged to receive a microwave signal from the sample space at the second port and to pass the majority of the received microwave signal to a third port. The amplifier has an input and an output; the input is arranged to receive the microwave signal from the third port of the directional coupler and to produce an amplified version of the received microwave signal at the output for transmission to a detector.

Abstract: Provided are 6-membered heteroaryl-containing aminopyridine compounds and pharmaceutically acceptable compositions thereof which exhibit inhibition activity against certain mutated forms of EGFR.

Abstract: Provided are 5-membered heteroaryl-containing aminopyridine compounds and pharmaceutically acceptable compositions thereof which exhibit inhibition activity against certain mutated forms of EGFR.

Abstract: The invention provides devices and methods for non-invasive monitoring and measuring of intraocular pressure (IOP) of a subject. Embodiments include a lens that is adapted to fit on the subject's eye, a microstructure disposed in or on the lens, the microstructure having at least one feature that exhibits a change in shape and/or geometry and/or position on the lens in response to a change in curvature of the lens. When the curvature of the lens changes in response to a change in IOP, a corresponding change in shape and/or geometry and/or position of the feature may be used to determine the change in IOP. The change in the feature is detectable in digital images of the lens taken with a mobile electronic device such as a smartphone.

Abstract: Optics grabbing devices that can hold and manipulate optical elements such as lenses or mirrors. Grabbers of the inventive subject matter have two flat surfaces with teeth on opposite sides, which can grip the edges of the optical element. The teeth are designed to prevent damage to the optical element and to allow a user to align it precisely with other grabbers or with other mechanisms. Grabbers can be used for various optical applications that require precise positioning and handling of optical elements.

Abstract: A system and method for optimizing power consumption of energy harvesting nodes in a wireless sensor network. In one embodiment, a system includes a network coordinator. The network coordinator includes a wireless transceiver and a controller. The wireless transceiver is configured to provide access to the wireless sensor network. The controller is configured to determine whether a wireless device that is wirelessly communicating with the network coordinator is powered via energy harvesting. The controller is also configured to schedule, based on a determination that the wireless device is powered via energy harvesting, the wireless device to communicate via the wireless sensor network using a priority timeslot of a superframe of the wireless sensor network. The priority timeslot is a timeslot occurring in an initial portion of the superframe.

Abstract: A system and method for reducing energy consumption in a wireless network. In one embodiment, a system includes a network coordinator configured to manage access to a wireless network. The network coordinator includes a controller. The controller is configured to define a channel hopping list that specifies on which channel a beacon signal is transmitted in each slot frame of the wireless network. The controller is also configured to set a number of time slots in each slot frame based on a length of the channel hopping list. The controller is further configured to transmit a first beacon signal in each slot frame on a channel specified by the channel hopping list. The number of slots in each slot frame causes the first beacon signal to be transmitted on a same channel in each slot frame.

Abstract: A computer-implemented method is disclosed. The method comprises managing, by a processor, a connected entity graph of nodes and edges, each node of the nodes representing an entity having an entity type of a plurality of entity types, at least one node of the nodes having an entity type of an electronic note, each edge of the edges representing a relationship between two entities; receiving a request for a search specifying a beginning entity, a linking parameter, and a filter on the linking parameter, the linking parameter specifying a property of an intermediary entity linking a source entity and a target entity during the search, the filter constraining a value of the property; searching the connected entity graph based on the request; causing a display of a search result.

Abstract: A system and method for optimizing power consumption of energy harvesting nodes in a wireless sensor network. In one embodiment, a system includes a network coordinator. The network coordinator includes a wireless transceiver and a controller. The wireless transceiver is configured to provide access to the wireless sensor network. The controller is configured to determine whether a wireless device that is wirelessly communicating with the network coordinator is powered via energy harvesting. The controller is also configured to schedule, based on a determination that the wireless device is powered via energy harvesting, the wireless device to communicate via the wireless sensor network using a priority timeslot of a superframe of the wireless sensor network. The priority timeslot is a timeslot occurring in an initial portion of the superframe.

Abstract: A system and method for reducing energy consumption in a wireless network. In one embodiment, a system includes a network coordinator configured to manage access to a wireless network. The network coordinator includes a controller. The controller is configured to define a channel hopping list that specifies on which channel a beacon signal is transmitted in each slot frame of the wireless network. The controller is also configured to set a number of time slots in each slot frame based on a length of the channel hopping list. The controller is further configured to transmit a first beacon signal in each slot frame on a channel specified by the channel hopping list. The number of slots in each slot frame causes the first beacon signal to be transmitted on a same channel in each slot frame.

Abstract: Disclosed are compounds of Formula 1, N-oxides of the compounds and salts of the compounds and N-oxides: wherein R1, R2, R3, R4, R5, R6, Q1, Q2, J, Y1, and Y2 are as defined in the disclosure. Also disclosed are compositions containing the compounds, N-oxides and salts, and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of such a compound. N-oxide, salt or composition.

Abstract: Systems and methods for facilitating interactions between a medical device (e.g., an imaging device, a surgical tool, a robotic arm, etc.) and a patient using radio frequency (RF) co-localization are provided. The systems include a radio-frequency (RF) interrogator system, one or more first RF target devices for coupling to a patient support for supporting a patient with respect to whom a medical device is to perform a task, and one or more second RF target devices for coupling to the medical device. A controller determines a position of the patient support within an RF interrogator system reference frame, a first position of the medical device within the RF interrogator system reference frame, a transformation between the RF interrogator system reference frame and a patient support reference frame, and a second position of the medical device within the patient support reference frame.

Abstract: A device includes hauling means for the movement of a payload while suspended from one or more lines. The or each line is suspended or suspendable from one end, the hauling means being provided at or in the region of the other end of the line/s and at which end the payload is situated in use.

Abstract: A bicycle carrier and attachment mechanism for folding bicycles utilizing either a rotating threaded connection mechanism or a sliding lock mechanism between the bicycle carrier and the back rack of a folding bicycle. The attachment mechanism enables a user to easily and releasably attach and detach the carrier to the back rack, such that the bicycle can be completely folded and more easily fit within storage containers or vehicular stowage areas.

Abstract: Techniques for visualizing dependencies in a data analytics system are described. In an embodiment, a visualization system may receive datasets and dataset dependency information for the datasets. The visualization system may receive a first type of analysis objects from a first analysis object system and dataset dependency information from an analysis object dependency service. The visualization system may receive a second type of analysis objects from a second analysis object system. The second type of analysis object may include a JSON representation of a set of operations that are applied during analysis such as a set of programming instructions. The visualization system may traverse and analyze the JSON representation to determine, for a given analysis object, one or more parent dependencies. The visualization system can then generate a graph of the datasets and analysis objects.

Abstract: The invention provides devices and methods for non-invasive monitoring and measuring of intraocular pressure (IOP) of a subject. Embodiments include a lens that is adapted to fit on the subject's eye, a microstructure disposed in or on the lens, the microstructure having at least one feature that exhibits a change in shape and/or geometry and/or position on the lens in response to a change in curvature of the lens. When the curvature of the lens changes in response to a change in IOP, a corresponding change in shape and/or geometry and/or position of the feature may be used to determine the change in IOP. The change in the feature is detectable in digital images of the lens taken with a mobile electronic device such as a smartphone.

Abstract: Provided are aminopyridine compounds and pharmaceutically acceptable compositions thereof which exhibit inhibition activity against certain mutated forms of EGFR.

Abstract: Disclosed are techniques for analyzing forensic data and remediating security incidents in a multi-tenant environment. The techniques comprises receiving the forensic data from a network by receiving a copy of data from each a computing device and a containerized systems which accesses the network, wherein the network includes a premises network and/or a cloud network. Further, processing the forensic data received from the network by determining if the network has been accessed by an unauthorized computing system by parsing the forensic data, wherein processing is performed by splitting the processing of the forensic data into a number of tasks and processing the number of tasks in overlapping time using a number of working resources, the group of working resources are scaled based on the number of tasks, Finally, processing the number of tasks if it is determining that the unauthorized computing device has accessed the network.