Abstract: The disclosure is directed to methods of treating cancer in subjects with a combination of a monoclonal antibody and (R)-N-(4-chlorophenyl)-2-(cis-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide, or a salt thereof.

Abstract: The disclosure is directed to methods of treating cancer in subjects with a combination of a monoclonal antibody and (R)-N-(4-chlorophenyl)-2-(cis-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide, or a salt thereof.

Abstract: A networked card for identifying and tracking animate and inanimate objects and personnel, the card including: a radio frequency modem operable at a low radio frequency not exceeding one megahertz, the modem including a full duplex transmitter and receiver; a loop antenna operatively coupled with the radio frequency modem, the antenna operable within a range of hundreds of feet; a programmable microprocessor operatively coupled with the radio frequency modem and fully programmable within a network; a memory operatively coupled with the programmable microprocessor, the memory holding identification data; and a battery for providing power to the microprocessor.

Abstract: A system has tags communicating by means of low frequency (below 1 megahertz) with routers which in turn communicate with nameservers. The tags have IP addresses, either explicitly programmed into the tags or associated in a virtual way with the tags. Lookups analogous to domain lookups permit human-friendly inquiries of tag status and location. Static (battery-backed) RAM in a tag permits great versatility in the localized function of the tag.

Abstract: A security tag affixed to a mobile phone for monitoring, tracking, and securing the mobile phone within a protected region. The security tag includes: a tag antenna operable at a low radio frequency not exceeding one megahertz; a tag transceiver operatively connected to the device antenna, the transceiver operable to receive radio signals at the low radio frequency and generate data signals at the said low radio frequency, in response thereto; and a microcontroller operatively coupled with the transceiver, the microcontroller being configured to cause the transceiver to emit a signal when the mobile phone is exiting the protected region.

Abstract: The invention relates to a method for assessing the field of vision, wherein FDF stimuli are produced and detected by a person using the at least one eye to be examined. The invention is based on the object of providing a novel method and a device in order to efficiently assess the field of vision of a person and/or in order to recognize early signs of disease processes, which can lead to limitations in the field of vision. For this purpose, the invention provides that the production of the FDF stimuli is carried out by utilizing a computer-controlled system for the efficient determination of the vision and that the respective FDF stimulus is generated by utilizing an imaging device.

Abstract: A system stores documents in a repository and includes a repository for storing data representing a document. An interface processor receives and stores document data representing a first document and an associated document identifier. A document processor automatically parses and processes the received document data to identify and store data indicating: (a) internal document structure and characteristics, and (b) external document relationships. The internal document structure and characteristics include a compilation of searchable keywords and key values. The external document relationships include an association or hierarchical relationship between the first document and one or more different documents.

Abstract: The invention relates to a method for assessing the field of vision, wherein FDF stimuli are produced and detected by a person using the at least one eye to be examined. The invention is based on the object of providing a novel method and a device in order to efficiently assess the field of vision of a person and/or in order to recognize early signs of disease processes, which can lead to limitations in the field of vision. For this purpose, the invention provides that the production of the FDF stimuli is carried out by utilizing a computer-controlled system for the efficient determination of the vision and that the respective FDF stimulus is generated by utilizing an imaging device.

Abstract: A networked card for identifying and tracking animate and inanimate objects and personnel, the card including: a radio frequency modem operable at a low radio frequency not exceeding one megahertz, the modem including a full duplex transmitter and receiver; a loop antenna operatively coupled with the radio frequency modem, the antenna operable within a range of hundreds of feet; a programmable microprocessor operatively coupled with the radio frequency modem and fully programmable within a network; a memory operatively coupled with the programmable microprocessor, the memory holding identification data; and a battery for providing power to the microprocessor.

Abstract: A dictionary system provides a term repository supporting the operation of an enterprise, which dynamically updates its content in response to system use. An input processor acquires transaction message data in at least one of a plurality of different data formats. A data processor parses the acquired transaction message data to extract a term from the message data. The processor then compares the extracted term to terms in a first term repository. The first term repository is updated to include the extracted term if the extracted term is absent from said first term repository. A communication processor intermittently processes the content of said first term repository to be suitable for communication to a second term repository.

Abstract: A two-tiered networked card for identifying and tracking animate and inanimate objects and personnel includes: some components housed in a thick tier of the card and other components housed in the thin tier of the card. The components are: a radio frequency modem operable at a low radio frequency, a loop antenna, a programmable microprocessor, a memory, and a connector for a battery.

Abstract: A system for storing documents in a repository includes a repository for storing data representing a document. An interface processor receives and stores document data representing a first document and an associated document identifier. A document processor automatically parses and processes the received document data to identify and store data indicating: (a) internal document structure and characteristics, and (b) external document relationships. The internal document structure and characteristics include a compilation of searchable keywords and key values. The external document relationships include an association or hierarchical relationship between the first document and one or more different documents.

Abstract: A dictionary system provides a term repository supporting the operation of an enterprise, which dynamically updates its content in response to system use. An input processor acquires transaction message data in at least one of a plurality of different data formats. A data processor parses the acquired transaction message data to extract a term from the message data. The processor then compares the extracted term to terms in a first term repository. The first term repository is updated to include the extracted term if the extracted term is absent from said first term repository. A communication processor intermittently processes the content of said first term repository to be suitable for communication to a second term repository.

Abstract: A system for providing a generic healthcare data repository includes an input processor for acquiring healthcare transaction message data in at least one of a plurality of different data formats. A data processor extracts message content type and patient associated identifier information from the transaction message data, processes the transaction message data for storage in a structured repository in a location specified using the patient associated identifier information. A storage processor stores the processed transaction message data in the structured repository.

Abstract: A polymer-drug conjugate, in which the polymer is the polysaccharide dextrin, linked directly or indirectly to the drug, is effective to deliver the drug to a target site and is biodegradable. The conjugate may be prepared by succinoylating dextrin followed by reaction with the drug or a derivative thereof.

Abstract: A computer system having servers and coupled to a network supports a distributed directory and a directory monitor service. The monitor service may include a domain analyzer and domain model at each of several servers; and, a network administrator and network model on an enterprise server of the network. A domain analyzer monitors the network to detect messages associated with directory operations initiated or performed by the same or another server in the network. Methods performed by one or more servers predict system and network failures. One such method includes receiving a first message, receiving a second message, and conditionally raising an alert condition. The first message indicates the beginning of a replication of a portion of a directory and indicates a beginning time. The second message indicates completion of the replication of the portion of the directory and indicates an ending time.

Abstract: A large panel surface planer is provided. The planer has a flat platform d as a mounting base. A pair of channel rails are clamped to the mounting base using c-clamps at the ends of each channel rail. A workpiece is secured to the flat platform using one or more pairs of back-to-back clamps which clamp both the workpiece and the flat platform. A pair of rectangular guide bars are clamped to and aligned orthogonally with the channel rails using a c-clamp at each end of each guide bar. A tool stop is also clamped at the channel rail-guide bar intersection providing both a tool stop and a spacer for alignment of the spacing between the guide bars. A cutting tool, such as a router, is then manually moved across the surface of the workpiece using the guide bar to hold the tool in position (both height and lateral position). After planing a particular set position, it is necessary to manually reposition the guide bar for the next cut and to continue sequentially until the entire workpiece has been planed.

Abstract: An ejection pump apparatus of a torpedo launching system is provided with improved water piston which is more stable during use and which enables the intake end of the water cylinder and the sea valve to have a smaller diameter than that of the piston. In order to assemble the piston through the smaller diameter opening, the piston is segmented into four pie-shaped segments which are assembled together in adjacent relation with bolt fasteners that extend through the sidewalls of the segments. The outer wall of the piston includes a circumferential slot which divides the outer wall into two spaced bearing lands which provide the piston with more stability. The circumferential slot also enable water to flow through the sidewall of the piston into the piston and outwardly through an open top thereof.

Abstract: A cascade orificial resistive device for throttling fluid flow which minies acoustic noise and internal vibrations is described herein. The device has a hollow body defining a fluid passageway, a plurality of perforated plates mounted within the passageway, a fixed end ring adjacent one end of the perforated plates, and a threadable end ring adjacent an opposite end of the perforated plates to place the plates in compression. Each of the perforated plates is a single piece molded plate having an integral outer ring and an integrally formed center keying mechanism as well as a plurality of orifices. The keying mechanism formed on each plate is designed so that adjacent ones of the plates have their orifices misaligned. In this manner, a pressure drop across each plate is created and the fluid flow through the device is throttled. The device of the present invention has utility in a number of onboard marine vessel systems wherein reduced acoustic noise and internal vibrations are particularly desirable.

Abstract: A self-actuating slide valve system for launching a device in a fluid envnment is provided. An interior channel, in which the device is positioned, is provided with first and second openings in its radial walls for allowing the passage of pressurized fluid into the interior channel. The first opening is located at least partially behind a tail end of the device and the second opening is located forward of the first opening. A sleeve is slidably fitted within a portion of the interior channel and around at least a portion of the device. The sleeve is movable between at least a first and second position. In the first position, the sleeve prevents the pressurized fluid from entering the interior channel through the first opening. In the second position, the sleeve allows the pressurized fluid to enter the interior channel through the first opening whereby the pressurized fluid can act on the tail end of the device to launch same through an axial opening of the interior channel.