Patents by Inventor James Chen

James Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240042033
    Abstract: Disclosed is a method of treating a tumor in a patient, comprising (a) administering riluzole in an amount effective to sensitize the tumor cells to ionizing radiation, and (b) irradiating the tumor cells with ionizing radiation in a dose effective to reduce tumor cell growth. The method can further comprise administering an effective amount of one or more additional therapeutic agents.
    Type: Application
    Filed: October 18, 2023
    Publication date: February 8, 2024
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Atif J. Khan, Suzie Chen, James S. Goydos, Bruce G. Haffty
  • Publication number: 20240048231
    Abstract: A method for setting a calibration signal power, the method including: transmitting a calibration-modulated wave (CMW) signal at a frequency slot; receiving a power measurement of the CMW signal; calculating a calibration correction factor for the frequency slot based on the power measurement; and adjusting a transmission power of the CMW signal at the frequency slot based on the calibration correction factor. A method for switching over a control channel and a voice channel from an old sub-band to a new-sub-band, the method including: switching over control channel and voice channel among multiple GW components and satellite payload; predicting switchover time to reduce control channel and voice channel outage time during switchover.
    Type: Application
    Filed: May 17, 2023
    Publication date: February 8, 2024
    Applicant: Hughes Network Systems, LLC
    Inventors: Bin CHEN, James Jehong Jong, Mostafa TARRAH
  • Publication number: 20240046374
    Abstract: Systems, media, and methods for automated response to social queries comprising: monitoring queries from users, each query submitted to a vendor via an interactive chat feature of an external electronic communication platform, monitoring human responses to the queries, monitoring subsequent communications conducted via the electronic communication platform until each query is resolved; applying a first machine learning algorithm to the monitored communications to identify a query susceptible to response automation; applying a second machine learning algorithm to the query susceptible to response automation to identify one or more responses likely to resolve the query; and either i) notifying a human to respond to the query susceptible to response automation with the one or more responses likely to resolve the query, or ii) instantiating an autonomous software agent configured to respond to the query susceptible to response automation with the one or more responses likely to resolve the query.
    Type: Application
    Filed: June 7, 2023
    Publication date: February 8, 2024
    Applicant: LIVEPERSON, INC.
    Inventors: Andrew Thomas BUSEY, Anthony Dan CHEN, Isao Uchida JONAS, Douglas James DANIELS, JR., Benjamin Edward LAMM
  • Publication number: 20240048415
    Abstract: A method for frequency and time synchronization with respect to a satellite, the method including: calculating a frequency offset ({circumflex over (f)}B,e) due to an instability of a satellite oscillator from a beacon signal (fB,TXN); determining a Satellite Motion Doppler Correction for Ephemeris (SMDCe) of a satellite motion based on ephemeris data for the satellite; computing a Satellite Reference Drift Correction for Ephemeris (SRDCe) based on the frequency offset, the beacon signal and the SMDCe; setting a loopback TX frequency based on the SMDCe and the SRDCe; and transmitting a loopback TX signal to the satellite at the loopback TX frequency.
    Type: Application
    Filed: April 21, 2023
    Publication date: February 8, 2024
    Applicant: Hughes Network Systems, LLC
    Inventors: James Jehong Jong, Bin CHEN, Tahereh FAZEL
  • Patent number: 11894323
    Abstract: A packaged radio-frequency device can include a packaging substrate configured to receive one or more components, the packaging substrate including a first side and a second side. The packaging substrate may include a first component mounted on the first side and a first overmold structure implemented on the first side, the first overmold structure substantially encapsulating the first component. The packaging substrate may further include a set of through-mold connections implemented on the second side of the packaging substrate, the set of through-mold connections including signal pins and ground pins, a second component mounted on the second side of the packaging substrate, the second component being located in an area of the second side configured to implement a redundant ground pad or a redundant portion of a ground pad, and a second overmold structure substantially encapsulating one or more of the second component or the set of through-mold connections.
    Type: Grant
    Filed: October 4, 2021
    Date of Patent: February 6, 2024
    Assignee: Skyworks Solutions, Inc.
    Inventors: Howard E. Chen, Robert Francis Darveaux, Anthony James Lobianco
  • Publication number: 20240036043
    Abstract: The present disclosure relates to a method for identifying cells that express antigen-specific antibodies with a high binding affinity for a monomeric antigen. Using fluorescence activated cell sorting, cells expressing high affinity antigen-specific antibodies are selected from a population of immune cells isolated from a mammal that has been immunized with or otherwise exposed to the antigen. Nucleic acids encoding the high affinity antibodies can then be cloned into other lymphoid and non-lymphoid cells where the antibody can be expressed and from which the antibodies can be secreted.
    Type: Application
    Filed: October 2, 2023
    Publication date: February 1, 2024
    Applicant: Regeneron Pharmaceuticals, Inc.
    Inventors: Gang CHEN, Robert BABB, James P. FANDL
  • Publication number: 20240034000
    Abstract: A method of forming a three-dimensional object is described. The method may use a polymerizable liquid, or resin, useful for the production by additive manufacturing of a three-dimensional object, comprising a mixture of (i) a light polymerizable liquid first component, and (ii) a second solidifiable component that is different from said first component.
    Type: Application
    Filed: May 30, 2023
    Publication date: February 1, 2024
    Inventors: Jason P. Rolland, Kai Chen, Justin Poelma, James Goodrich, Robert K. Pinschmidt, JR., Joseph M. DeSimone, Lloyd M. Robeson
  • Publication number: 20240026530
    Abstract: Embodiments disclosed herein include to a component support for use in coating chamber components via chemical vapor deposition (CVD). The component support includes contact rods configured to contact chamber components at fixture points located on the backside of the chamber components. The component supports are configured to support the chamber components in the processing volume with minimal contact of the chamber components. The fixture points on the backside reduce exposure of the fixture points to reactant gases when the chamber components are installed.
    Type: Application
    Filed: July 20, 2022
    Publication date: January 25, 2024
    Inventors: Kirk Allen FISHER, John Ford, James M. Amos, Hui Chen, Shawn Joseph Bonham, Xinning Luan, Philip Michael Amos, Aimee S. Erhardt, Cathryne A. Ryan, Michael R. Riordan
  • Publication number: 20240030684
    Abstract: A VC SEL can include: a substrate that passes light therethrough; a phase matching layer over a top mirror stack; a first metal layer over the phase matching layer; and an end metal region over the first metal layer. The phase matching layer and first metal layer have a cooperative thickness to provide reflectivity of at least a predetermined reflectivity threshold for the emission wavelength. A method of making a VCSEL can include: providing a substrate; forming a first mirror stack above the substrate; forming an active region above the first mirror stack; and forming a reflective end above the active region, the reflective end having a phase matching layer and a first metal layer. The phase matching layer and first metal layer have a combined thickness for the reflective end to have a reflectivity of at least a predetermined reflectivity threshold for an emission wavelength of the VCSEL.
    Type: Application
    Filed: October 3, 2023
    Publication date: January 25, 2024
    Inventors: James K. GUENTER, Hao CHEN
  • Publication number: 20240026033
    Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
    Type: Application
    Filed: March 31, 2023
    Publication date: January 25, 2024
    Applicant: Genentech, Inc.
    Inventors: Yongmei Chen, James Ernst, Hok Seon Kim, Junichiro Sonoda, Christoph Spiess, Scott Stawicki, Yan Wu
  • Patent number: 11881553
    Abstract: A solid-state electrolyte membrane includes an interlocking layered microstructure formed by melting and spraying of ionic conductive material for use in a battery system.
    Type: Grant
    Filed: September 23, 2020
    Date of Patent: January 23, 2024
    Assignee: Ampcera Inc.
    Inventors: Hui Du, James Emery Brown, Chen Chen, Sumin Zhu
  • Patent number: 11882632
    Abstract: A multi-channel power supply system including a power supply circuit configured to generate a drive signal for powering a plurality of color channels based on an input power signal, a first current control circuit coupled to a first color channel of the plurality of color channels and configured to adjust a first channel current of the first color channel based on the drive signal and a first reference signal, and a channel controller configured generate the first reference signal based on a color temperature according to a black body curve.
    Type: Grant
    Filed: September 13, 2021
    Date of Patent: January 23, 2024
    Assignee: ERP POWER, LLC
    Inventors: Michael Archer, Louis Chen, James H. Mohan
  • Patent number: 11877842
    Abstract: A communication device comprising: a first unit having a first antenna, a second antenna, and a first signal transmitting and receiving circuitry; a second unit having a third antenna, a fourth antenna, and a second signal transmitting and receiving circuitry, wherein the second unit is located in proximity to the first unit; and wherein the second unit is capable of receiving signals at a first signal frequency, down converting the signals to a second signal frequency, and relaying the signals through a barrier to the first unit. Wherein the first signal frequency is in the millimeter wave range and the second signal frequency is in the microwave range.
    Type: Grant
    Filed: March 14, 2022
    Date of Patent: January 23, 2024
    Assignee: Micro Mobio Corporation
    Inventors: Zlatko Aurelio Filipovic, Weiping Wang, Adam James Wang, Guan-Wu Wang, Yi-Hung Chen
  • Publication number: 20240018553
    Abstract: Expression-enhancing nucleotide sequences for eukaryotic expressions systems are provided that allow for enhanced and stable expression of recombinant proteins in eukaryotic cells. Genomic integration sites providing enhanced expression and methods of use thereof are provided for expression of a gene of interest in a eukaryotic cell. Chromosomal loci, sequences, and vectors are provided for enhanced and stable expression of genes in eukaryotic cells.
    Type: Application
    Filed: September 6, 2023
    Publication date: January 18, 2024
    Applicant: Regeneron Pharmaceuticals, Inc.
    Inventors: Ying Shen, Darya Burakov, Gang Chen, James P. Fandl
  • Publication number: 20240017385
    Abstract: A clip apparatus is provided for use with a faucet tool. The faucet tool has an elongated body. The clip apparatus includes a biasing member structured to be coupled to and flex with respect to the elongated body, a light emitting component coupled to the biasing member, a power source located internal with respect to the biasing member and configured to energize the light emitting component, and a button mechanism coupled to the biasing member and configured to activate the power source in order to energize the light emitting component.
    Type: Application
    Filed: July 14, 2023
    Publication date: January 18, 2024
    Inventors: Chungeng Chen, James Stobar
  • Publication number: 20240018508
    Abstract: The present invention relates to a method for determining an extent of cyclisation of a peptide ligand displayed on a genetic display system, wherein the peptide ligand comprises a polypeptide covalently linked to a molecular scaffold at two or more amino acid residues, comprising the steps of exposing the polypeptide displayed on the genetic display system to the molecular scaffold, wherein said polypeptide comprises two or more peptide reactive groups on said two or more amino acid residues which form covalent bonds with the molecular scaffold at two or more scaffold reactive groups, to give the peptide ligand; removing unreacted molecular scaffold from the genetic display system; exposing the peptide ligand displayed on the genetic display system to a first probe, wherein the first probe binds to a first unconjugated reactive group on the peptide ligand; and measuring the first unconjugated reactive group on the peptide ligand.
    Type: Application
    Filed: October 2, 2020
    Publication date: January 18, 2024
    Inventors: Michael SKYNNER, James COOKE, Emma CRAWLEY, Liuhong CHEN, Gemma MUDD, Paul BESWICK
  • Publication number: 20240019551
    Abstract: In some implementations, a light detection and ranging (LIDAR) system includes a vertical cavity surface emitting laser (VCSEL) array including a plurality of VCSELs. The VCSEL array may have a first aspect ratio. The LIDAR system may include a set of transmission optics configured to receive light from the VCSEL array and to illuminate a field of view having a second aspect ratio that is greater than the first aspect ratio. The LIDAR system may include an image sensor array configured for line readout. The image sensor array may have a third aspect ratio that is different from the first aspect ratio. The LIDAR system may include a set of reception optics configured to image light reflected from objects in the field of view, having the second aspect ratio, onto the image sensor array having the third aspect ratio.
    Type: Application
    Filed: October 7, 2022
    Publication date: January 18, 2024
    Inventors: James CHEN, Michael MILLER, Eric R. HEGBLOM, Lijun ZHU, Paul COLBOURNE
  • Publication number: 20240022842
    Abstract: A system such as a vehicle, building, vessel, aircraft, or electronic device system may have a layer of material with invisible laser-drilled openings. The layer of material may include an outer layer of fabric overlapping an inner layer such as an inner foam layer. Laser-drilled openings may include outer openings in the fabric layer and inner openings in the foam layer. Each of the inner openings may be overlapped by multiple outer openings. The exposed surface of the fabric layer may have strands of material of different appearances and/or may otherwise be configured to help visually hide the laser-drilled openings. Laser-drilled openings may also have small sizes to help make the laser-drilled openings invisible. Laser-drilled openings may overlap components such as audio components, heating and cooling components, and/or light-emitting components.
    Type: Application
    Filed: September 27, 2023
    Publication date: January 18, 2024
    Inventors: James G. Griffin, II, Lukas Satas, Michael S. Nashner, Zuguang Chen, Jason T. Parker
  • Publication number: 20240017350
    Abstract: A laser-processing apparatus can carry out a process to form a via in a workpiece, having a first material formed on a second material, by directing laser energy onto the workpiece such that the laser energy is incident upon the first material, wherein the laser energy has a wavelength to which the first material is more reflective than the second material. The apparatus can include a back-reflection sensing system operative to capture a back-reflection signal corresponding to a portion of laser energy directed to the workpiece and reflected by the first material and generate a sensor signal based on the captured back-reflection signal; and a controller communicatively coupled to an output of the back-reflection sensing system, wherein the controller is operative to control a remainder of the process by which the via is formed based on the sensor signal.
    Type: Application
    Filed: November 23, 2021
    Publication date: January 18, 2024
    Applicant: ELECTRO SCIENTIFIC INDUSTRIES, INC.
    Inventors: Jan KLEINERT, Ruolin CHEN, James BROOKHYSER, Mark UNRATH, Honghua HU
  • Patent number: 11872318
    Abstract: Nanocrystals, compositions, and methods that aid particle transport in mucus are provided. In some embodiments, the compositions and methods involve making mucus-penetrating particles (MPP) without any polymeric carriers, or with minimal use of polymeric carriers. The compositions and methods may include, in some embodiments, modifying the surface coatings of particles formed of pharmaceutical agents that have a low water solubility. Such methods and compositions can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for administration routes involving the particles passing through a mucosal barrier.
    Type: Grant
    Filed: January 23, 2023
    Date of Patent: January 16, 2024
    Assignee: The Johns Hopkins University
    Inventors: Alexey Popov, Elizabeth M. Enlow, James Bourassa, Colin R. Gardner, Hongming Chen, Laura M. Ensign, Samuel K. Lai, Tao Yu, Justin Hanes, Ming Yang