Abstract: Provided is a method for treating a target tissue in a subject by using a particle beam, or further in combination with a reactant. The method includes irradiating the target tissue with the particle beam by scanning under a controlled path in the target tissues.

Abstract: The present disclosure provides methods of treating a biological tissue using a proton beam. A method includes the steps of: irradiating a proton beam to a biological tissue containing a reactant. The reactant includes a composite. The composite reacts with at least one proton from the proton beam and releases at least one ? particle or ? rays. The ? particle or ? rays reacts with the biological tissue. Another method includes the steps of: providing a reactant, the reactant comprising a composite; introducing the reactant into a biological tissue, the reactant being distributed in the biological tissue; and irradiating the biological tissue with the proton beam. The composite reacts with at least one proton from the proton beam to release at least one ? particle or ? rays, and the ? particle or the ? rays reacts with the biological tissue.

Abstract: The present disclosure recites a method of treating biological tissues. The method includes using a proton beam includes irradiating a proton beam to a biological tissue containing a reactant. The reactant includes a first composite and a second composite. The first composite reacts with at least one proton from the proton beam and then releases at least one neutron inside the biological tissue. The second composite reacts with the at least one said neutron to release at least one ? particle or ? rays, and said ? particle or said ? rays to react with the biological tissue.

Abstract: The present disclosure provides methods of treating a biological tissue using a proton beam. A method includes the steps of: irradiating a proton beam to a biological tissue containing a reactant. The reactant includes a composite. The composite reacts with at least one proton from the proton beam and releases at least one ? particle or ? rays. The ? particle or ? rays reacts with the biological tissue. Another method includes the steps of: providing a reactant, the reactant comprising a composite; introducing the reactant into a biological tissue, the reactant being distributed in the biological tissue; and irradiating the biological tissue with the proton beam. The composite reacts with at least one proton from the proton beam to release at least one ? particle or ? rays, and the ? particle or the ? rays reacts with the biological tissue.

Abstract: The present disclosure recites a method of treating biological tissues. The method includes using a proton beam includes irradiating a proton beam to a biological tissue containing a reactant. The reactant includes a first composite and a second composite. The first composite reacts with at least one proton from the proton beam and then releases at least one neutron inside the biological tissue. The second composite reacts with the at least one said neutron to release at least one ? particle or ? rays, and said ? particle or said ? rays to react with the biological tissue.