Patents by Inventor James Clarke

James Clarke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11392848
    Abstract: A qubit assembly includes a first superconducting loop comprising a first Josephson junction and a second Josephson junction, a second superconducting loop comprising the second Josephson junction and a third Josephson junction, and a third superconducting loop comprising the third Josephson junction and a fourth Josephson junction. A flux source is configured to provide a control flux to the second superconducting loop, such that the effective commutation relations between a first quantum operator corresponding to current in the first superconducting loop and a second quantum operator corresponding to current in the third superconducting loop can be changed by changing a magnitude of the control flux provided to the second superconducting loop by the flux source.
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: July 19, 2022
    Assignee: NORTHROP GRUMMAN SYSTEMS CORPORATION
    Inventor: David James Clarke
  • Publication number: 20220217042
    Abstract: Methods, systems, and devices for wireless communications are described. In some systems, a user equipment (UE) may transmit assistance information to a base station to request an update or a modification to one or more communication parameters configured at the UE. Such communication parameters may include a quantity of uplink multiple-input multiple-output (MIMO) layers, a quantity of downlink MIMO layers, a minimum scheduling offset, a maximum quantity of component carriers, or a maximum aggregated bandwidth for a secondary cell group (SCG). In some implementations, the UE may transmit the assistance information requesting the update or modification to one or more of such communication parameters based on detecting that the UE satisfies one or more triggering conditions or thresholds.
    Type: Application
    Filed: January 6, 2021
    Publication date: July 7, 2022
    Inventors: Arvind Vardarajan Santhanam, Brian Clarke Banister, Kuo-Chun Lee, Aamod Khandekar, Enoch Shiao-Kuang Lu, Satashu Goel, Daniel Amerga, Karthik Venkatram, Subashini Krishnamurthy, Xuepan Guan, Mouaffac Ambriss, Peter Pui Lok Ang, James Francis Geekie, Sasikanth Reddy Adapata, Sundaresan Tambaram Kailasam
  • Publication number: 20220139722
    Abstract: Apparatus and methods are disclosed for sample preparation, suitable for online or offline use with multilayer samples. Ion beam technology is leveraged to provide rapid, accurate delayering with etch stops at a succession of target layers. In one aspect, a trench is milled around a region of interest (ROI), and a conductive coating is developed on an inner sidewall. Thereby, reliable conducting paths are formed between intermediate layers within the ROI and a base layer, and stray current paths extending outside the ROI are eliminated, providing better quality etch progress monitoring, during subsequent etching, from body or scattered currents. Ion beam assisted gas etching provides rapid delayering with etch stops at target polysilicon layers. Uniform etching at deep layers can be achieved. Variations and results are disclosed.
    Type: Application
    Filed: January 19, 2022
    Publication date: May 5, 2022
    Applicant: FEI Company
    Inventors: James Clarke, Micah LeDoux, Jason Lee Monfort, Brett Avedisian
  • Publication number: 20220127669
    Abstract: The invention relates to a new method of sequencing a double stranded target polynucleotide. The two strands of the double stranded target polynucleotide are linked by a bridging moiety. The two strands of the target polynucleotide are separated using a polynucleotide binding protein and the target polynucleotide is sequenced using a transmembrane pore.
    Type: Application
    Filed: October 8, 2021
    Publication date: April 28, 2022
    Applicant: Oxford Nanopore Technologies Ltd.
    Inventors: Clive Gavin Brown, James Clarke, Graham Hall, Gavin Harper, Andrew John Heron, James White
  • Publication number: 20220064722
    Abstract: The invention relates to constructs comprising a transmembrane protein pore subunit and a nucleic acid handling enzyme. The pore subunit is covalently attached to the enzyme such that both the subunit and enzyme retain their activity. The constructs can be used to generate transmembrane protein pores having a nucleic acid handling enzyme attached thereto. Such pores are particularly useful for sequencing nucleic acids. The enzyme handles the nucleic acid in such a way that the pore can detect its component nucleotides by stochastic sensing.
    Type: Application
    Filed: June 23, 2021
    Publication date: March 3, 2022
    Applicant: Oxford Nanopore Technologies Ltd.
    Inventors: Lakmal Jayasinghe, John Hagan Pryce Bayley, Stephen Cheley, Brian McKeown, James White, James Clarke
  • Patent number: 11257683
    Abstract: Apparatus and methods are disclosed for sample preparation, suitable for online or offline use with multilayer samples. Ion beam technology is leveraged to provide rapid, accurate delayering with etch stops at a succession of target layers. In one aspect, a trench is milled around a region of interest (ROI), and a conductive coating is developed on an inner sidewall. Thereby, reliable conducting paths are formed between intermediate layers within the ROI and a base layer, and stray current paths extending outside the ROI are eliminated, providing better quality etch progress monitoring, during subsequent etching, from body or scattered currents. Ion beam assisted gas etching provides rapid delayering with etch stops at target polysilicon layers. Uniform etching at deep layers can be achieved. Variations and results are disclosed.
    Type: Grant
    Filed: June 17, 2020
    Date of Patent: February 22, 2022
    Assignee: FEI Company
    Inventors: James Clarke, Micah LeDoux, Jason Lee Monfort, Brett Avedisian
  • Publication number: 20210292376
    Abstract: The invention relates to mutant forms of CsgG. The invention also related to analyte detection and characterisation using CsgG.
    Type: Application
    Filed: March 8, 2021
    Publication date: September 23, 2021
    Applicants: Oxford Nanopore Technologies Ltd., VIB VZW, Vrije Universiteit Brussel
    Inventors: Stefan Howorka, Han Remaut, Lakmal Jayasinghe, Elizabeth Jayne Wallace, James Clarke, Richard George Hambley, Jonathan Bankes Pugh
  • Patent number: 11094358
    Abstract: An apparatus is described. The apparatus includes a semiconductor chip that includes logic circuitry, embedded dynamic random access memory (DRAM) cells and embedded ferroelectric random access memory (FeRAM) cells.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: August 17, 2021
    Assignee: Intel Corporation
    Inventors: Ilya Karpov, Yih Wang, Fatih Hamzaoglu, James Clarke
  • Patent number: 11083806
    Abstract: Provided are radiopaque compositions comprising one or more of yttrium (Y), strontium (Sr), gallium (Ga), and silicon, or oxides and salts thereof. The composition can comprise a combination of Y2O3, SrO, Ga2O3, and SiO2, and optionally MnO2, and TiO2. Other compositions comprise SrO, Ga2O3, TiO2, MnO2, and SiO2. The composition can be a particulate material. The compositions are useful for radioembolization to treat tumors.
    Type: Grant
    Filed: November 26, 2015
    Date of Patent: August 10, 2021
    Assignee: ABK Biomedical Incorporated
    Inventors: Daniel Boyd, Robert Joseph Abraham, Xiaofang Zhang, Sharon Legere, James Clarke
  • Patent number: 11069509
    Abstract: The backside of a planar view lamella is prepared from a sample extracted from a workpiece. The sample includes multiple device layers and a substrate layer. After removing at least a part of the substrate layer covering a final device layer to obtain a sample surface, a region of interest (ROI) relative to the sample surface is alternately scanned with an electron beam and spontaneously etched until the final device layer within the ROI is exposed. One or more device layers may be removed from the sample backside after the final device layer is exposed to obtain the backside of the planar view lamella.
    Type: Grant
    Filed: March 16, 2020
    Date of Patent: July 20, 2021
    Assignee: FEI Company
    Inventors: James Clarke, Brian Routh, Jr., Micah LeDoux, Cliff Bugge
  • Patent number: 10972595
    Abstract: A base station for an audio headset system is provided which is able to communicate with a remote device. The base station is configured to be convertible such that it facilitates communication with remote devices over a range of different communication protocols, in accordance with varying user preference.
    Type: Grant
    Filed: April 13, 2019
    Date of Patent: April 6, 2021
    Inventor: James Clarke
  • Patent number: 10909189
    Abstract: Described herein is a system and method for embedding an electronic file in a document canvas of an application. User input of an electronic file to be embedded in a document canvas of an application is received. Information regarding the electronic file to be embedded, a target page and/or a user is analyzed to determine parameter(s) regarding representation of the electronic file in the document canvas. The electronic file is embedded in the document canvas of the application in accordance with the determined at least one parameter regarding representation of the electronic file in the document canvas.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: February 2, 2021
    Assignee: Microsoft Technology Licensing, LLC
    Inventor: Christopher James Clarke
  • Publication number: 20210015866
    Abstract: This disclosure provides methods of treating cancer or eliciting an anti-tumor response in a subject by administering an effective amount of a population of T-cells that exhibits higher or lower than baseline expression of one or more genes. In other aspects, methods are provided to diagnose cancer and determine prognosis of cancer patients. Also provided are methods to identify the antigens or antigen receptors associated with the isolated and/or purified cell populations that elicit a more positive prognosis.
    Type: Application
    Filed: March 22, 2019
    Publication date: January 21, 2021
    Applicants: La Jolla Institute for Allergy and Immunology, University of Southampton
    Inventors: Pandurangan VIJAYANAND, Christian OTTENSMEIER, James CLARKE, Tilman SANCHEZ-ELSNER, Simon ESCHWEILER, Ferhat AY
  • Publication number: 20200410590
    Abstract: The subject of the invention is an insurance claim and/or financial transaction processing system for parametric risk related claims and/or performance warranty related transactions that can be processed using transparency and in a rapid manner wherein the performance or insurance is transacted using sensors and/or analytics. The invention also includes a marketplace where parties can enter or leave, buy or sell, a transaction or transactions associated with an insurance or financial transaction. The system enables aggregation and/or distribution of risk, performance obligations or investments, and aggregation/distribution and/or syndication of insurers or bankers, crowdsourcing/crowdfunding and/or participation of individuals and small groups within the transaction system. The integration of investment, insurance risk conditionalities and performance guarantees within a single exchangeable system is also envisioned. Transaction re-risking and de-risking and associated payments or payouts is also envisioned.
    Type: Application
    Filed: June 25, 2020
    Publication date: December 31, 2020
    Applicant: Resilience Financing Inc.
    Inventors: Pusker Regmi, Daniel Medina, Kieran Iyengar, Sudhir Murthy, James Clarke
  • Publication number: 20200401922
    Abstract: A qubit assembly includes a first superconducting loop comprising a first Josephson junction and a second Josephson junction, a second superconducting loop comprising the second Josephson junction and a third Josephson junction, and a third superconducting loop comprising the third Josephson junction and a fourth Josephson junction. A flux source is configured to provide a control flux to the second superconducting loop, such that the effective commutation relations between a first quantum operator corresponding to current in the first superconducting loop and a second quantum operator corresponding to current in the third superconducting loop can be changed by changing a magnitude of the control flux provided to the second superconducting loop by the flux source.
    Type: Application
    Filed: June 19, 2019
    Publication date: December 24, 2020
    Applicant: NORTHROP GRUMMAN SYSTEMS CORPORATION
    Inventor: DAVID JAMES CLARKE
  • Publication number: 20200402813
    Abstract: Apparatus and methods are disclosed for sample preparation, suitable for online or offline use with multilayer samples. Ion beam technology is leveraged to provide rapid, accurate delayering with etch stops at a succession of target layers. In one aspect, a trench is milled around a region of interest (ROI), and a conductive coating is developed on an inner sidewall. Thereby, reliable conducting paths are formed between intermediate layers within the ROI and a base layer, and stray current paths extending outside the ROI are eliminated, providing better quality etch progress monitoring, during subsequent etching, from body or scattered currents. Ion beam assisted gas etching provides rapid delayering with etch stops at target polysilicon layers. Uniform etching at deep layers can be achieved. Variations and results are disclosed.
    Type: Application
    Filed: June 17, 2020
    Publication date: December 24, 2020
    Applicant: FEI Company
    Inventors: James Clarke, Micah LeDoux, Jason Lee Monfort, Brett Avedisian
  • Patent number: 10808231
    Abstract: The invention relates to modified helicases with reduced unbinding from polynucleotides. The helicases can be used to control the movement of polynucleotides and are particularly useful for sequencing polynucleotides.
    Type: Grant
    Filed: July 18, 2013
    Date of Patent: October 20, 2020
    Assignee: Oxford Nanopore Technologies Limited
    Inventors: Andrew Heron, James Clarke, Ruth Moysey, Elizabeth Jayne Wallace, Mark Bruce, Lakmal Jayasinghe, Domenico Caprotti, Szabolcs Soeroes, Luke McNeill, David Alves, Rebecca Bowen, John Milton
  • Patent number: 10770895
    Abstract: A power distribution system such as a marine power distribution and propulsion system. The system includes an ac busbar and a plurality of active front end power converters. Each AFE power converter includes a first active rectifier/inverter connected to the busbar and a second active rectifier/inverter connected to an electrical load such as an electric propulsion motor. Power sources are connected to the dc link of the AFE power converters and can be operated under the control of a power management controller or power management system.
    Type: Grant
    Filed: September 17, 2013
    Date of Patent: September 8, 2020
    Assignee: GE Energy Power Conversion Technology Ltd.
    Inventors: Nicholas James Clarke, Stephen Paul Hudson
  • Publication number: 20200231547
    Abstract: The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification. The compounds are apelin and APJ agonists for treating cardiovascular diseases. Preferred compounds are 2-(1,1?-biphe-1H-benzo[d]imidazole derivatives. The invention further provides compositions comprising the compounds and the compounds for use in methods of medical treatment.
    Type: Application
    Filed: August 16, 2018
    Publication date: July 23, 2020
    Inventors: Shun Su, Hannguang J. Chao, Adam James Clarke, R. Michael Lawrence
  • Patent number: 10715513
    Abstract: Methods and systems are provided that enable single sign-on (SSO) mechanisms on rich clients running hosting applications that include documents with one or more embedded web assets. An embedded web asset may be any resource (e.g., document, image, data, etc.) that is accessed via a browser from within a hosting application. In aspects, authentication of a user identity is required to access an embedded web asset. In particular, an identity management module is provided on a rich client. The identity management module is configured to maintain multiple credentials for multiple user identities that are associated with multiple applications, whether the applications are embedded applications or hosting applications. In this way, a user may access multiple applications, including embedded web assets, associated with each user identity—without signing into each application. That is, a user is able to login a single time for each user identity.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: July 14, 2020
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Abdullah Rubiyath, Fanguang Kong, Huanhuan Xia, Ryan Christopher McMinn, Christopher James Clarke, Prashant Thiruvengadachari