Abstract: A medical treatment device includes an elongate member having an internal volume, a proximal end, and a distal end, the internal volume extending from the proximal end to the distal end. The medical treatment device further includes a first coupler and a second coupler, the first coupler and the second coupler coupled to the internal volume of the elongate member; a first joining member and a second joining member, the first joining member coupled to the first coupler and the second joining member coupled to the second coupler. The first joining member is configured to attach to a first biological matter location, and the second joining member is configured to attach to a second biological matter location, the second location being distal to the first location. The second coupler is configured for manipulation to align relative the first coupler such that the second biological matter location relocates adjacent the first biological matter location.

Abstract: A sealer for a sample testing instrument is disclosed that cuts and seals a fluid conduit that connects a test sample device with a fluid receptacle containing a fluid sample. The sealer includes an enclosure and a protective shield to protect a user or technician from contact with the cutting element assembly in the sealer. The cutting element assembly includes a spring-loaded element that engages the test sample device and holds it in a fixed position while a cutting element (e.g., hot wire) cuts the fluid conduit. A motor driving the cutting element assembly is positioned at an angle having both vertical and horizontal components, whereby adjustment of the motor firmware allows for adjustment of the position of the cutting element relative to the instrument in both horizontal and vertical directions.

Abstract: A system and method for generating a three-dimensionally perceived image from a stereo endoscope by at least one viewer include an autostereoscopic display having a left projector and a right projector that project corresponding left and right images received from corresponding left and right cameras of a stereo endoscope to a holographic optical element functioning as a Bragg diffraction grating to redirect light from the left projector to a left eye-box and to redirect light from the right projector to a right eye-box for viewing by left and right eyes of a viewer to create three-dimensionally perceived autostereoscopic image without glasses or optical headgear.

Abstract: An integrated instrument processes fluid test samples using disposable test devices. The test devices are carried in a carrier. The instrument includes a vacuum station receiving the carrier for batch loading of the test devices with fluid samples to be tested. The user removes the carrier from the vacuum station and inserts it into a loading station of a separate carrier and test device processing subsystem. This subsystem includes a transport system moving the carrier through the instrument where various modules perform operations on the test devices, including sealing the test devices, loading the test devices into an incubation station, incubation of the test devices, test device reading, and test device disposal.

Abstract: A method, system and apparatus for imaging an oral cavity of a subject include a bracket comprising a mouthpiece and a camera mount. The mouthpiece has upper and lower bite guides disposed on a posterior side and separated by an opening through the mouthpiece. The bite guides are spaced apart so a subject biting on the guides opens the oral cavity to inspection through the opening. The mount is disposed on an anterior side of the mouthpiece; and has a flange to engage and slide along the opening and an optical path for light to pass through the mount and mouthpiece. A clip on an anterior side of the mount is configured to removeably hold a camera to record light passing through the optical path from the posterior side of the mount. In one embodiment, the camera is a programmable cell phone with digital camera.

Abstract: A multiwell plate device is provided having a frame, a substantially flat substrate and a multiwell structure supported by the substrate. The multiwell structure includes multiple bottomless wells formed therein. The substrate is supported by the frame and may be processed by an automated arrayer or instrument that is used to print or spot arrays in a pattern on a reaction surface of the substrate. Thereafter, the multiwell structure may be engaged with the substrate and the multiwell structure and substrate may be engaged with the frame in an upright orientation. For scanning or other analysis, the multiwell structure and substrate may be disengaged from the frame, inverted 180°, and then reengaged with the frame in the inverted orientation.

Abstract: An example method includes displaying a first control and a second control, wherein a touch associated with the controls results in moving an indicator through information in a first direction and in a second direction, in response to the detecting a first touch associated with the first control, moving the indicator in the first direction, and in response to detecting a second touch associated with the second control, moving the indicator in the first direction.

Abstract: An example method includes associating a first area of a non-display area of a touch-sensitive display with a first control, wherein a touch associated with the first control results in moving an indicator through the information in a first direction and in a second direction. The method may also include associating a second area of the non-display area with a second control, wherein a touch associated with the second control results in moving the indicator through the information in the first direction and in the second direction. The method may also include detecting a first touch associated with the first control, in response to detecting the first touch, moving the indicator in the first direction, detecting a second touch associated with the second control, and in response to detecting the second touch, moving the indicator in the first direction.

Abstract: Systems and methods for generating a three-dimensionally perceived image from a stereo endoscope by at least one viewer include an autostereoscopic display having a left projector and a right projector that project corresponding left and right images received from corresponding left and right cameras of the stereo endoscope onto a reflective holographic optical element that redirects light from the left projector to a left viewing zone for a left eye and redirects light from the right projector to a right viewing zone for a right eye of a viewer to create a three-dimensionally perceived image without glasses or optical headgear.

Abstract: A medical treatment device includes an elongate member having an internal volume, a proximal end, and a distal end, the internal volume extending from the proximal end to the distal end. The medical treatment device further includes a first coupler and a second coupler, the first coupler and the second coupler coupled to the internal volume of the elongate member; a first joining member and a second joining member, the first joining member coupled to the first coupler and the second joining member coupled to the second coupler. The first joining member is configured to attach to a first biological matter location, and the second joining member is configured to attach to a second biological matter location, the second location being distal to the first location. The second coupler is configured for manipulation to align relative the first coupler such that the second biological matter location relocates adjacent the first biological matter location.

Abstract: The present invention is directed to a method and automated loading mechanism for loading an apparatus. The apparatus of the present invention may include a means for automated loading, a means for automated transfer and/or a means for automated unloading of a container (e.g., a specimen container). In one embodiment, the apparatus can be an automated detection apparatus for rapid non-invasive detection of a microbial agent in a test sample. The detection system also including a heated enclosure, a holding means or rack, and/or a detection unit for monitoring and/or interrogating the specimen container to detect whether the container is positive for the presence of a microbial agent.

Abstract: The present invention is directed to a method and automated transfer means for transferring a container within an apparatus. The apparatus of the present invention may include a means for automated loading, a means for automated transfer and/or a means for automated unloading of a container (e.g., a specimen container). In one embodiment, the apparatus can be an automated detection apparatus for rapid non-invasive detection of a microbial agent in a test sample. The detection system also including a heated enclosure, a holding means or rack, and/or a detection unit for monitoring and/or interrogating the specimen container to detect whether the container is positive for the presence of a microbial agent. In other embodiment, the automated instrument may include one or more, bar code readers, scanners, cameras, and/or weighing stations to aid in scanning, reading, imaging and weighing of specimen containers within the system.

Abstract: A method and automated apparatus for rapid non-invasive detection of a microbial agent in a test sample is described herein. The apparatus may include one or more means for automated loading, automated transfer and/or automated unloading of a specimen container. The apparatus also includes a detection system for receiving a detection container, e.g., container or vial, containing a biological sample and culture media. The detection system may also include one or more heated sources, holding structures or racks, and/or a detection unit for monitoring and/or interrogating the specimen container to detect whether the container is positive for the presence of a microbial agent therein. In other embodiment, the automated instrument may include one or more, bar code readers, scanners, cameras, and/or weighing stations to aid in scanning, reading, imaging and weighing of specimen containers within the system.

Abstract: Systems and methods for generating a three-dimensionally perceived image from a stereo endoscope by at least one viewer include an autostereoscopic display having a left projector and a right projector that project corresponding left and right images received from corresponding left and right cameras of the stereo endoscope onto a reflective holographic optical element that redirects light from the left projector to a left viewing zone for a left eye and redirects light from the right projector to a right viewing zone for a right eye of a viewer to create a three-dimensionally perceived image without glasses or optical headgear.

Abstract: Apparati and methods for generating a three-dimensionally perceived image from a stereo endoscope by at least one viewer include an autostereoscopic display having a left projector and a right projector that project corresponding left and right images received from corresponding left and right cameras of a stereo endoscope through a transmissive holographic optical element functioning as a Bragg diffraction grating to redirect light from the left projector to a left eye-box and to redirect light from the right projector to a right eye-box for viewing by left and right eyes of a viewer to create a three-dimensionally perceived image without glasses or optical headgear.

Abstract: An integrated instrument processes fluid test samples using disposable test devices. The test devices are carried in a carrier. The instrument includes a vacuum station receiving the carrier for batch loading of the test devices with fluid samples to be tested. The user removes the carrier from the vacuum station and inserts it into a loading station of a separate carrier and test device processing subsystem. This subsystem includes a transport system moving the carrier through the instrument where various modules perform operations on the test devices, including sealing the test devices, loading the test devices into an incubation station, incubation of the test devices, test device reading, and test device disposal.

Abstract: A carrier for holding up to N test sample devices as they are moved through a sample testing instrument. Each of the test sample devices are held in a receiving structure such as a slot in the carrier. The carrier also includes N optical interrupt positioning features, each placed in registry with one of the receiving structures (and thereby in registry with the test sample device). The instrument includes fixed optical interrupt sensors for detecting the position of the positioning feature as the carrier is moved through the instrument. In the illustrated embodiment, the position features comprise voids formed in a rib on the lower surface of the carrier. The optical interrupt sensors are positioned below the path the carrier travels over, whereby as the carrier moves past the sensor the voids, and hence position of the test sample devices, are detected.

Abstract: A transport system is provided for a sample testing machine. The transport system includes a carrier holding a set of test sample devices and a drive subsystem for moving the carrier through the sample testing machine. The drive subsystem includes a reciprocating motor-driven block engaging the carrier and moving the carrier back and forth in a predetermined longitudinal path extending along a longitudinal axis from an entrance station to a plurality of processing stations in the sample testing machine. The processing stations are accessed as the carrier is moved along the path. The carrier includes features in the form of slots that are detected by strategically placed optical interrupt sensors. As the carrier moves, the slots are detected by the sensors to thereby continuously track the position of the carrier and the test devices as they are moved through the instrument.

Abstract: A transport system is provided for a sample testing machine. The transport system includes a carrier holding a set of test sample devices and a drive subsystem for moving the carrier through the sample testing machine. The drive subsystem includes a reciprocating motor-driven block engaging the carrier and moving the carrier back and forth in a predetermined longitudinal path extending along a longitudinal axis from an entrance station to a plurality of processing stations in the sample testing machine. The processing stations are accessed as the carrier is moved along the path. The carrier includes features in the form of slots that are detected by strategically placed optical interrupt sensors. As the carrier moves, the slots are detected by the sensors to thereby continuously track the position of the carrier and the test devices as they are moved through the instrument.

Abstract: A sealer for a sample testing instrument is disclosed that cuts and seals a fluid conduit that connects a test sample device with a fluid receptacle containing a fluid sample. The sealer includes an enclosure and a protective shield to protect a user or technician from contact with the cutting element assembly in the sealer. The cutting element assembly includes a spring-loaded element that engages the test sample device and holds it in a fixed position while a cutting element (e.g., hot wire) cuts the fluid conduit. A motor driving the cutting element assembly is positioned at an angle having both vertical and horizontal components, whereby adjustment of the motor firmware allows for adjustment of the position of the cutting element relative to the instrument in both horizontal and vertical directions.