Abstract: A medicament delivery device includes a housing, a container disposed within the housing and configured to contain medicament, a plunger slidably disposed within the container, a plunger rod configured to push the plunger through the container to dispense the medicament when the container contains medicament, and a gas canister configured to travel with the plunger rod and containing a compressed gas, wherein the gas canister is configured to release the compressed gas to drive the plunger rod to dispense the medicament out of a distal end of the container.

Abstract: This disclosure generally relates to novel processes for the preparation of drug linker compounds and compositions comprising such drug linker compounds. The presently disclosed methods for synthesizing Fmoc-Val-Cit-PABOH and related compounds have also been found to minimize formation of diastereomeric impurities.

Abstract: A storage bag is secured to a conventional garment such as a vest by a novel attachment system. A securing strap is interlaced through interdigitated fabric loops located on both the storage bag and the garment. The securing strap is permanently secured to the bag. The securing strap is configured to release the storage bag from the garment by a simple pulling of the strap away from the garment, the storage bag being drawn away, upon separation, by the securing bag. The system allows one-handed release and separating of a storage bag secured to a garment.

Abstract: A marine waste water dump control system for noncommercial nonmetallic or fiberglass boats that provides a system and process for automatically monitoring the time, exact location, and quantity of blackwater, greywater or bilgewater (marine water waste) is dumped from such a water vessel and for requesting and receiving approval or disapproval for dumping marine water waste into restricted or unrestricted waters, including oil water and the like. The instant invention has an MS (Automatic Information System) or comparable communication system that operates at approximately 160 MHz for determining the exact distance from shore and communicating with marine authorities, such as the Coast Guard, before activating the dump control system and communication. The dump control system of the instant invention automatically stores all dumping related information in memory for access by authorities at any time in the event a vessel does not include an AIS or a working AIS.

Abstract: A device for storing emergency-use articles on a safety vest or similar garment in a manner that presents the articles for easy access and use. A harness including multiple flexible strap arms is securable, using hook-and-loop material, to both front and back surfaces of a chest panel of a conventional safety vest. Storage tubes of flexible material are captured by threading one respective strap arm through each tube. The tubes are sized to retain within them an emergency-use article such as a tourniquet.

Abstract: Multiple test coupons are incorporated in the construction of a personal garment for the purpose of determining the presence of foreign substances acquired during garment use or a change in properties or other change in characteristics over time. Each of the test coupons is retained with the garment during the useful life of the garment until the coupon is individually removed for test purposes. Each test coupon has a construction identical to the garment construction and is easily removable and configured to allow for destructive testing. Sufficient multiple coupons are provided with each garment over its life to allow for periodic testing.

Abstract: A personal ballistic protection device incorporates multiple removable test coupons. Each of the test coupons are retained with the ballistic device during its use until each coupon is removed for test purposes. Each test coupon has a construction identical to the protective portions of the ballistic device and is removable and configured to allow for destructive testing. Sufficient coupons are provided with the ballistic protection device to allow for periodic testing over a predetermined useful life of the ballistic protection device. One embodiment of the device is a body armor vest.

Abstract: A pump for a dialysis machine, the pump having a pump chamber and a deformable membrane actuable to pump a fluid from the pump chamber, the pump chamber being substantially conical such that the membrane is actuated to extend into the conical chamber in order to pump the fluid from the chamber.

Abstract: A personal ballistic protection device incorporates multiple removable test coupons. Each of the test coupons are retained with the ballistic device during its use until each coupon is removed for test purposes. Each test coupon has a construction identical to the protective portions of the ballistic device and is removable and configured to allow for destructive testing. Sufficient coupons are provided with the ballistic protection device to allow for periodic testing over a predetermined useful life of the ballistic protection device. One embodiment of the device is a body armor vest.

Abstract: Multiple test coupons are incorporated in the construction of a personal garment for the purpose of determining the presence of foreign substances acquired during garment use or a change in properties or other change in characteristics over time. Each of the test coupons is retained with the garment during the useful life of the garment until the coupon is individually removed for test purposes. Each test coupon has a construction identical to the garment construction and is easily removable and configured to allow for destructive testing. Sufficient multiple coupons are provided with each garment over its life to allow for periodic testing.

Abstract: A method of preparing a dialysate solution for hemodialysis, the method including the steps of providing a mixing pump comprising a pump chamber covered by an actuable membrane, the chamber having a first inlet for admitting water into the chamber, a second inlet for admitting dialysate base solution into the chamber, and an outlet from the chamber, the method including the further steps of providing pump means for dispensing a predetermined volume of dialysate solution base into the chamber at a first pressure, actuating the membrane to draw a volume of water or water mix into the mixing pump chamber at a second pressure, wherein the magnitude of the first pressure is higher than the magnitude of the second pressure so as to ensure the complete dispense of the dialysate solution base into the chamber.

Abstract: A non-coring needle that includes a sharpened and hardened tip having a tapered back region against which a length of tubing is pressed and welded, brazed or soldered. A Luer Lock hub may be attached to the other end of the tubing.

Abstract: A novel device and method provides personal protection from ballistic weapons such as handguns and rifles. A single piece of high-strength ballistic fabric that may be cut from a bulk roll by a single cutting step is folded in layers over and around multiple separate sheets of vinyl to produce a ballistic resistance assembly. The device may be incorporated into personal articles such as garments.

Abstract: Methods and apparatus enable monitoring a mobile data service, and in particular monitoring an operational status of a relationship between a mobile gateway account on a mobile gateway and a mailbox on a messaging server. The operational status may be based on an initialization state of the mobile gateway account on a mobile gateway and a mailbox status of an associated mailbox on a messaging server. In one embodiment, the mailbox status may be determined based on mailbox errors indicative that a mobile gateway is unable to access the mailbox on the messaging server. In one embodiment a mobile gateway detects mailbox errors based on mailbox protocol error messages and sends an error notification to a monitoring system. Also provided are error notifications for facilitating, in a monitoring system, the correlation of mailbox errors with mobile gateway accounts.

Abstract: A pump for a dialysis machine, the pump having a pump chamber and a deformable membrane actuable to pump a fluid from the pump chamber, the pump chamber being substantially conical such that the membrane is actuated to extend into the conical chamber in order to pump the fluid from the chamber.

Abstract: A pressure sensor for a dialysis machine, the sensor having a body and a sensing surface, the sensor surface configured to detect the pressure of a fluid across an elastic membrane, the sensor in use generating a vacuum between the sensing surface and the membrane so as to draw the membrane into contact with the sensing surface, wherein the elastic membrane is further retained in use between a sealing surface on the dialysis machine and a membrane engaging surface on the body of the sensor.

Abstract: A method of preparing a dialysate solution for hemodialysis, the method including the steps of providing a mixing pump comprising a pump chamber covered by an actuable membrane, the chamber having a first inlet for admitting water into the chamber, a second inlet for admitting dialysate base solution into the chamber, and an outlet from the chamber, the method including the further steps of providing pump means for dispensing a predetermined volume of dialysate solution base into the chamber at a first pressure, actuating the membrane to draw a volume of water or water mix into the mixing pump chamber at a second pressure, wherein the magnitude of the first pressure is higher than the magnitude of the second pressure so as to ensure the complete dispense of the dialysate solution base into the chamber.

Abstract: A non-coring needle that includes a sharpened and hardened tip having a tapered back region against which a length of tubing is pressed and welded, brazed or soldered. A Luer Lock hub may be attached to the other end of the tubing.

Abstract: Methods and apparatus enable monitoring a mobile data service, and in particular monitoring an operational status of a relationship between a mobile gateway account on a mobile gateway and a mailbox on a messaging server. The operational status may be based on an initialization state of the mobile gateway account on a mobile gateway and a mailbox status of an associated mailbox on a messaging server. In one embodiment, the mailbox status may be determined based on mailbox errors indicative that a mobile gateway is unable to access the mailbox on the messaging server. In one embodiment a mobile gateway detects mailbox errors based on mailbox protocol error messages and sends an error notification to a monitoring system. Also provided are error notifications for facilitating, in a monitoring system, the correlation of mailbox errors with mobile gateway accounts.

Abstract: Liquid dietary supplements include vitamins, macro minerals, trace minerals, high Oxygen Radical Absorption Capacity (ORAC) compounds, and optionally fulvates. Despite the tendency of minerals in such a liquid mineral and vitamin supplement to precipitate and for the ingredients to quickly degrade, particularly at high ORAC values and low pH, embodiments of the invention stay in solution have a desired shelf life without degrading. In part, this is achieved through the use of the natural preservative Momordica, carefully formulated amounts of the various ingredients, and high-tech processing.