Abstract: MiniVectors and compositions containing MiniVectors that target genes implicated in IPF selected from CDH11, STAT3, STAT6, FoxM1, MDM2, TGF?, SMAD, PDGFA, or TLR4 and/or increase intracellular levels of reduced glutathione, relaxin, and p53, are provided, along with uses in the treatment of idiopathic pulmonary fibrosis.

Abstract: MiniVectors and compositions containing MiniVectors that are ultrapure, and methods of making and using ultrapure MiniVectors for gene therapy uses, including long term repeated gene therapy uses.

Abstract: Described herein are examples of a surface cleanup tool. The surface cleanup tool includes a collection area. The surface cleanup tool also includes an intake ramp formed at an edge of the surface cleanup tool along the collection area to facilitate intake of debris from a floor to the collection area; a retention lip to resist loss of debris from the collection area. The surface cleanup tool also includes handles formed proximate opposite sides of the collection area to facilitate lifting of the surface cleanup tool from the floor. The surface cleanup tool has a combination of weight and friction, relative to the floor, to remain in place in response to a sweeping force applied to move the debris up the intake ramp and onto the collection area.

Abstract: Foldable frame devices designed to transport fishing equipment and assorted items while functioning as a table and which are capable of being stored in confined spaces are disclosed. In an aspect, a foldable frame device may be carried by a user. The foldable frame device includes a rotating flat surface area which may be moved between a folded position and a usable position. In the folded position, the foldable frame device has a compact profile, thereby occupying a small amount of space for transportation or storage when not in use. In the usable position, the flat surface area extends away from the frame and may support items, such as fishing equipment.

Abstract: Foldable frame devices designed to transport fishing equipment and assorted items while functioning as a table and which are capable of being stored in confined spaces are disclosed. In an aspect, a foldable frame device may be carried by a user. The foldable frame device includes a rotating flat surface area which may be moved between a folded position and a usable position. In the folded position, the foldable frame device has a compact profile, thereby occupying a small amount of space for transportation or storage when not in use. In the usable position, the flat surface area extends away from the frame and may support items, such as fishing equipment.

Abstract: A dual function exercise machine, enabling unilateral and bilateral exercise of a limb, includes a pair of lever arms pivotally mounted adjacent to each other on a frame. Each lever arm is slidably mounted through a separate linear bearing sleeve at a point remote from the pivot point and is associated with a separate and independent stack of weights. Each weight stack is slidably mounted on guide bars of the frame. Each sleeve is pivotally connected to a selector bar which is adapted to connect a number of weights to the sleeve to provide resistance during either unilateral or bilateral exercise of a limb. In this manner, one or both corresponding limbs may be exercised with the same or different number of weights connected to each lever arm.