Abstract: A compound of formula (I), or a salt or prodrug thereof, is described, wherein G is attached at position 3 or 4 of the piperidine ring and represents halogen or C.sub.1-6 alkoxy; R1 represents C.sub.3-6 alkenyl, C.sub.3-6 alkynyl, aryl(C.sub.1-6)alkyl or heteroaryl (C.sub.1-6)alkyl, any of which groups may be optionally substituted; processes for its preparation and its use in therapy, particularly in the treatment of migraine.

Abstract: A portable data device employs an integrated circuit having a signal processor that receives a power signal from an external source via a power node. A decoupling device is placed between the power node and the signal processor. An energy reservoir is placed in parallel with the signal processor, which acts in concert with the decoupling device to isolate the effects of the signal processor from the rest of the integrated circuit.

Abstract: An integrated circuit chip is fabricated as several circuit modules that are synchronized with a clock signal, by the following steps. Initially, a hardware description language is used to describe a functional behavior for a first module on the chip which generates an intermodule signal, and describe a functional behavior for a second module on the chip which processes the intermodule signal. Thereafter, a slow circuit embodiment of the first module is synthesized with port timing constraints which permit the intermodule signal to be generated in twice the cycle time T.sub.CY of the clock signal, and a slow circuit embodiment of the second module is synthesized with port timing constraints which permit the intermodule signal to be processed in twice the cycle time of the clock. Then, a timing analysis program is run on the slow circuit embodiment of the first and second modules to thereby obtain a first delay .DELTA..sub.1 in which the intermodule signal is actually generated, and obtain a second delay .

Abstract: A pair of leg guards for sports, particularly of the type worn by hockey players under elastic socks, each includes rigid plastic shin and knee guard sections. A thigh guard section is joined continuously to the knee guard section. The shin guard section has front and rear panels. A channel is molded preferably diagonally across the front panel in which a rigid plastic strap protector is affixed. The strap protector has a slot through which a one-piece elastic strap passes to detachably secure the guard to the wearer's leg. The one-piece elastic strap has horizontal and diagonal strap portions which wrap around the back of the knee and lower leg respectively of the wearer and connect to the shin guard section by hook and loop connectors. The rear panel and the inside of the knee guard section are fitted and affixed continuously with a detachable liner for further protection of the wearer's leg and to enhance the life of the guard.

Abstract: A direct melt spinning process for providing high filament count fine filament polyester yarns having excellent mechanical quality and along-end uniformity and unitary interlace by spinning all the filaments of such high filament count yarn from a single spinneret. Such yarns may be used as direct-use yarns and as draw-feed yarns for preparing drawn flat yarns and draw-textured yarns.

Abstract: A class of substituted pyrimidine derivatives are ligands for dopamine receptor subtypes within the body and are therefore useful in the treatment of disorders of the dopamine system, in particular schizophrenia ##STR1##

Abstract: A direct melt spinning process for providing high filament count fine filament polyester yarns having excellent mechanical quality and along-end uniformity and unitary interlace by spinning all the filaments of such high filament count yarn from a single spinneret. Such yarns may be used as direct-use yarns and as draw-feed yarns for preparing drawn flat yarns and draw-textured yarns.

Abstract: Polyester mixed fine filament yarns having excellent mechanical quality and uniformity, and preferably with a balance of good dyeability and shrinkage, are prepared by a simplified direct spin-orientation process by selection of polymer and spinning conditions.

Abstract: A class of fused tricyclic heteroaromatic compounds of formula (I), or a salt thereof or a prodrug thereof containing a fused pyrazole ring are ligands for dopamine receptor subtypes within the body and are therefore of use in the treatment and/or prevention of disorders of the dopamine system, such as schizophrenia.

Abstract: The present invention provides a rain gutter debris shield/run-off water control embodiment for standard residential roof rain gutters, thereby eliminating the myriad debris problems associated thereto, a vertical deflector embodiment means has herein been designed, developed and tested which comprises a diminutive configuration exhibiting extensive adaptability and delivering optimum performance utilizing scientific principles underlying the hydrophilic phenomenon, an integrally constructed embodiment functionally dependent upon a unique vertical deflector exhibiting outstanding water deflection and debris rejection/ejection capabilities, a horizontal capillary cap delivering optimal water leveling and spreading requirements, a roof slope adaptor and its alternate means accommodate every and all roof slope/gutter juxtaposition, thereby eliminating traditional installation problems, a support stabilizer functions to provide stability and rigidity, while preserving the integrity of critical embodiment dimensio

Abstract: A game projectile of unique contour adapted to be manually thrown in a plurality of trajectories. The combination of elements of the game projectile allows for minimal displacement path of the projectile subsequent to being dynamically impacted by a bat or stick member. The game projectile includes a first hemispherical contoured member which is formed of a resilient composition and is substantially symmetrical about a first vertically directed axis line. The game projectile further includes a second hemispherically contoured member having a radius less than the radius of the first hemispherically contoured member. The second hemispherically contoured member is formed in one piece formation with the first hemispherically contoured member on an external surface thereof in order to provide the pitcher with various gripping mechanisms to control the trajectory of the game projectile.

Abstract: The disclosed article (e.g. a sanitary napkin) typically comprises (1) an elongated absorbent pad, (2) an outer covering layer in adherent contact with at least one surface of the pad, (3) an adhesive strip or layer on the exposed surface of the outer layer, and (4) a release liner for protecting the adhesive layer. The adhesive layer is useful for removably attaching the article to the inside of an undergarment or the like. Production of the article can be greatly simplified by using a hot-melt pressure sensitive adhesive (PSA) as the adhesive layer. However, the rubbery base for the hot-melt PSA should be very carefully selected. Two types of rubbery polymers provide good results, i.e. (a) an A-B-A block copolymer having polystyrene end blocks and a rubbery poly(ethylene-butylene) midblock and (b) a radial teleblock copolymer with branches having polystyrene terminal blocks and a butadiene segment in the center.

Abstract: A hot melt composition is used to form a closure liner, e.g. the circular, integral, gasket-like member adhered to the periphery of a circular top or closure for a food jar or the like. The hot melt composition is selected to have, in the solid state, sufficient deformabilty, resiliency, hardness, lubricity, and other requirements of closure liners. It has been found that silicone oil, used in a concentration of about 1-8% by weight of the total hot melt composition can provide a high degree of lubricity, similar to the type of lubricity in self-lubricated plastic bearings. The remainder of the hot melt system or composition generally comprises a rubbery block co-polymer (serving as a film former), a hydrocarbon wax, a hydrocarbon oil, and, if desired, a thermoplastic vinyl arene polymer such as poly(methylstyrene).

Abstract: Compounds of the formula ##STR1## wherein R.sub.1 and R.sub.2 are each hydrogen or lower alkyl, R.sub.3 represents lower alkyl and A is a monovalent group of formula: ##STR2## wherein Y is hydrogen or the acyl radical of a hydrocarbon carboxylic acid having from 2 to 18 carbon atoms, inclusive, are employed as anticonvulsants in treating mammals, including humans.Novel compounds within the scope of the above formula are also disclosed, wherein R.sub.1 is specifically lower alkyl and provided that R.sub.1 is located in a position ortho or meta to the substituent group A when R.sub.2 is hydrogen. Disclosed also are novel intermediate compounds for preparing the above-described novel compounds of the invention, which correspond thereto but wherein the group A is replaced by a nitro-group.

Abstract: The disclosed heterogeneous hot-melt sealant system is particularly well suited to sealing the typical tongue-and-groove joint between the base and cover of a burial vault. The hot-melt system comprises a plurality of layers, each layer being a distinct phase which resists chemical or morphological penetration (e.g. paraffin oil migration) from the adjacent layer. The layers are typically applied to the groove in the cover for the vault by individual casting or pouring of each of a plurality of hot-melt compositions in the molten state. Each hot-melt composition comprises an essentially amorphous polypropylene, a hydrocarbon resin (e.g. synthetic terpene resin), and a hydrocarbon (e.g. paraffin) oil. The first (bottom) poured hot-melt contains more polypropylene and less oil and terpene resin than the second (upper) pour.

Abstract: In a shaft angle encoder, an optical system translates the shaft angular displacement into a difference of two optical path lengths and that difference is measured by interferometry. Light from a monochromatic source is split and both the transmitted and reflected beams are passed along separate paths through an optical component that moves angularly with the shaft and varies the lengths of the separate paths differentially according to the shaft angular displacement. The transmitted and reflected beams are then recombined and the interference fringes in the recombined beam sensed by a detector.