Patents by Inventor James COMOLLI

James COMOLLI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multivalent liposome formulations
    Patent number: 9408890
    Abstract: This disclosure provides compositions, kits, and methods useful for treating or preventing viral and bacterial infection and reducing or preventing the effects of toxins. The methods comprise administering to a subject an effective amount of a liposomal composition.
    Type: Grant
    Filed: January 22, 2014
    Date of Patent: August 9, 2016
    Assignees: The Charles Stark Draper Laboratory, Inc., The Massachusetts Institute of Technology, University of California, Santa Barbara (UCSB), University of Massachusetts Medical School
    Inventors: James Comolli, Jose Trevejo, Ram Sasisekharan, Zachary Shriver, Karthik Viswanathan, Deborah Fygenson, Robert Finberg, Jennifer Wang
  • MULTIVALENT ANTIVIRAL COMPOSITIONS, METHODS OF MAKING, AND USES THEREOF
    Publication number: 20150158956
    Abstract: This disclosure provides compositions, kits, and methods useful for treating or preventing viral infection. The methods comprise administering to a subject an effective amount of a sulfated polysaccharide composition.
    Type: Application
    Filed: October 20, 2014
    Publication date: June 11, 2015
    Inventors: James Comolli, Robert Finberg, Deborah K. Fygenson, Zachary Shriver, Ram Sasisekharan, Jennifer Wang, Karthik Viswanathan
  • SYSTEM AND METHOD FOR ANALYZING TRANSMISSIBILITY OF INFLUENZA
    Publication number: 20150064689
    Abstract: The present disclosure provides systems and methods for determining the transmissibility of a pathogen. The system described herein includes a flow device with a plurality of cell culture chambers. Cells, such as primary human tracheal or bronchial epithelial cells, are cultured within the flow device. Cells within a first cell culture chamber are infected with the pathogen. The pathogen's transmissibility is determined by flowing a gas through the flow device such that the gas flows over the infected cells and then over uninfected cells in a second cell culture chamber of the device. By quantifying the amount of virus present in the cells of the second cell culture chamber after a predetermined amount of time, the transmissibility of the pathogen is determined.
    Type: Application
    Filed: August 29, 2013
    Publication date: March 5, 2015
    Inventor: James Comolli
  • MULTIVALENT LIPOSOME FORMULATIONS
    Publication number: 20140255470
    Abstract: This disclosure provides compositions, kits, and methods useful for treating or preventing viral and bacterial infection and reducing or preventing the effects of toxins. The methods comprise administering to a subject an effective amount of a liposomal composition.
    Type: Application
    Filed: January 22, 2014
    Publication date: September 11, 2014
    Applicant: The Charles Stark Draper Laboratory, Inc.
    Inventors: James Comolli, Jose Trevejo, Ram Sasissekharan, Zachary Shriver, Karthik Viswanathan, Deborah Fygenson, Robert Finberg, Jennifer Wang
  • Sterilization of polymeric materials
    Patent number: 8585965
    Abstract: A method of sterilizing a polymeric material that is sensitive to radiation. The method includes the steps of applying at least one radiosensitizer to the polymeric material and irradiating the polymeric material with a suitable radiation at an effective dose and time to sterilize the polymeric material. Also disclosed is a method of enhancing the ability of a medical device to withstand sterilization by radiation and a bioabsorbable polymeric medical device.
    Type: Grant
    Filed: November 26, 2012
    Date of Patent: November 19, 2013
    Assignee: Ethicon, Inc.
    Inventors: James Comolli, Stephen C. Yeadon
  • Sterilization of polymeric materials
    Patent number: 8580192
    Abstract: A method of sterilizing a polymeric material that is sensitive to radiation. The method includes the steps of applying at least one radiosensitizer to the polymeric material and irradiating the polymeric material with a suitable radiation at an effective dose and time to sterilize the polymeric material. Also disclosed is a method of enhancing the ability of a medical device to withstand sterilization by radiation and a bioabsorbable polymeric medical device.
    Type: Grant
    Filed: October 31, 2006
    Date of Patent: November 12, 2013
    Assignee: Ethicon, Inc.
    Inventors: James Comolli, Stephen C. Yeadon
  • STERILIZATION OF POLYMERIC MATERIALS
    Publication number: 20080101982
    Abstract: A method of sterilizing a polymeric material that is sensitive to radiation. The method includes the steps of applying at least one radiosensitizer to the polymeric material and irradiating the polymeric material with a suitable radiation at an effective dose and time to sterilize the polymeric material. Also disclosed is a method of enhancing the ability of a medical device to withstand sterilization by radiation and a bioabsorbable polymeric medical device.
    Type: Application
    Filed: October 31, 2006
    Publication date: May 1, 2008
    Applicant: ETHICON, INC.
    Inventors: James COMOLLI, Stephen C. YEADON