Abstract: A system and computer-implemented method for optimising, by a quantum computer, an allocation of opportunities to recipients comprising: determining a plurality of opportunities to be allocated; determining a plurality of recipients to be allocated at least one of the plurality of opportunities; determining a respective acceptance likelihood of each of the plurality of recipients accepting each of the plurality of opportunities; determining a first constraint associated with a cost acceptance of each of the plurality of opportunities by the plurality of recipients; and determining an optimised allocation of the opportunities to the recipients based on the respective likelihoods and the first constraint, in the quantum computer.

Abstract: A computer-implemented method for testing a model indicating a parametric relationship between a plurality of channels of multivariate data, the method comprising: obtaining a real dataset of observed multivariate data comprising the plurality of channels; generating a control dataset of multivariate data comprising the plurality of channels, the control dataset being generated based on the model; for each of a plurality of sample subsets from the real dataset and the control dataset, calculating a p-value for the model; and determining whether (1) a distribution difference characteristic of a distribution of the obtained p-values for sample subsets of the real dataset and a distribution of the obtained p-values for sample subsets of the control dataset falls within a second predetermined significance range, and, if condition (1) is met, determining that the model is accurate.

Abstract: A pipe coating removal apparatus (1) for removing all or some of the coating on a pipe, the pipe coating removal apparatus (1) having a pipe support means (2) for supporting a length of pipe. and further having a tool carriage (3). The tool carriage (3) being capable of supporting two or more different types of pipe coating removal tools (4), (5), (6), (7), (8), (80), (81), (82) and/or (70). The pipe coating removal apparatus (1) being capable of causing relative movement between the tool carriage (3) and the pipe support means (2) to remove all or some of the coating on the pipe that is supportable by the pipe support means (2).

Abstract: The present invention includes methods and compositions for the production of high titer recombinant Adeno-Associated Virus (rAAV) in a variety of mammalian cells. The disclosed rAAV are useful in gene therapy applications. Disclosed methods based on co-infection of cells with two or more replication-defective recombinant herpes virus (rHSV) vectors are suitable for high-titer, large-scale production of infectious rAAV.

Abstract: The present invention includes methods and compositions for the production of high titer recombinant Adeno-Associated Virus (rAAV) in a variety of mammalian cells. The disclosed rAAV are useful in gene therapy applications. Disclosed methods based on co-infection of cells with two or more replication-defective recombinant herpes virus (rHSV) vectors are suitable for high-titer, large-scale production of infectious rAAV.

Abstract: Interbody fusion systems and methods are provided. According to one embodiment, an interbody fusion system may include an interbody fusion device implantable in an interbody space of a spinal joint. The interbody fusion device may include a first component and a second component. The first component and the second component, together, may define a mating interface at which the first component and the second component are securable together with the first component and the second component both positioned entirely within the interbody space. The first component and the second component, together, may have at least a first cavity that is exposed on a superior side and on an inferior side of the interbody fusion device. The system may further include a first inserter securable to a first proximal end of the first component and a second inserter securable to a second proximal end of the second component.

Abstract: A pharmaceutical preparation for treating connective tissue damage in man and in animals, comprising a therapeutically effective amount of a glycosaminoglycan composition comprising chondroitin sulfate and hyaluronan, in combination with isolated stem cells. Methods of use and kits containing the glycosaminoglycan composition and materials for isolating stem cells and for treating connective tissue damage and repair of cartilage in man and in animals are also provided.

Abstract: The present invention includes methods and compositions for the production of high titer recombinant Adeno-Associated Virus (rAAV) in a variety of mammalian cells. The disclosed rAAV are useful in gene therapy applications. Disclosed methods based on co-infection of cells with two or more replication-defective recombinant herpes virus (rHSV) vectors are suitable for high-titer, large-scale production of infectious rAAV.

Abstract: A pharmaceutical preparation for treating connective tissue damage in man and in animals, comprising a therapeutically effective amount of a glycosaminoglycan composition comprising chondroitin sulfate and hyaluronan, in combination with isolated stem cells. Methods of use and kits containing the glycosaminoglycan composition and materials for isolating stem cells and for treating connective tissue damage and repair of cartilage in man and in animals are also provided.

Abstract: The present invention includes methods and compositions for the production of high titer recombinant Adeno-Associated Virus (rAAV) in a variety of mammalian cells. The disclosed rAAV are useful in gene therapy applications. Disclosed methods based on co-infection of cells with two or more replication-defective recombinant herpes virus (rHSV) vectors are suitable for high-titer, large-scale production of infectious rAAV.

Abstract: A pharmaceutical preparation for treating connective tissue damage in man and in animals, comprising a therapeutically effective amount of a glycosaminoglycan composition comprising chondroitin sulfate, N-acetyl D-glucosamine, and hyaluronan, in combination with isolated stem cells. Methods of use and kits containing the glycosaminoglycan composition and materials for isolating stem cells and for treating connective tissue damage and repair of cartilage in man and in animals are also provided.

Abstract: A pharmaceutical preparation for treating connective tissue damage in man and in animals, comprising a therapeutically effective amount of a glycosaminoglycan composition comprising chondroitin sulfate, N-acetyl D-glucosamine, and hyaluronan, in combination with isolated stem cells. Methods of use and kits containing the glycosaminoglycan composition and materials for isolating stem cells and for treating connective tissue damage and repair of cartilage in man and in animals are also provided.

Abstract: A lightweight portable ratcheting device allows a single workmen to remove a worn railroad tie in a more efficient and productive manner in about half the time now required by work crews using hand tools even in an inaccessible area.

Abstract: A system and method for configuring a controlling device to allow the controlling device to generate commands for commanding operations of a new appliance which new appliance was previously unable to be supported by the controlling device. The system and method uses a definition input into the controlling device to create a new device data set for use in generating commands to command operations of the new appliance. The new device data set is a new combination of elements selected from device data sets already stored within a memory of the controlling device.

Abstract: A customizable and an upgradable remote control is provided which may be customized or upgraded via a Web site or through other remote, and preferably interactive, processes. A database is provided which includes a plurality of functions of a consumer electronic device, such as a TV and/or a DVD player. A user selects among the plurality of functions at least one of the desired functions. In response to the user selection a virtual configuration is created to virtually configure the customizable remote control. The virtual configuration may be downloaded to the customizable remote control.

Abstract: A system and method for upgrading remote control application resident on a device. To this end, a markup language file is created. The markup language file has a representation of information used to setup the remote control application to communicate with an appliance. The markup language file may be executed, on the device or an intermediate client with which the device is synchronized, to upload the representation of the information to a remote server. At the remote server, the uploaded information is used to automatically display user-selectable, downloadable data files relevant to the control of the appliance. Downloaded data files, which may include command codes and/or graphical user interface elements, may be used within the device to upgrade the ability of the remote control application to communicate with the appliance. The information uploaded to the server may also be used to generate demographic data regarding consumer preferences.

Abstract: A clip of the present invention comprises a unitary body having an intermediate section and a first pair of opposing arms with each of the arms having an end portion, the body having an interior surface and an exterior surface, a second pair of opposing arms formed on the exterior surface of the body, each of the second pair of opposing arms having an end portion with the second pair of opposing arms being located between one of the first pair of opposing arms and the intermediate section.

Abstract: A hand-held electronic device having a remote control application user interface that functions to displays operational mode information to a user. The graphical user interface may be used, for example, to setup the remote control application to control appliances for one or more users in one or more rooms, to perform activities, and to access favorites. The remote control application is also adapted to be upgradeable. Furthermore, the remote control application provides for the sharing of operational mode information.

Abstract: A system and method for upgrading remote control application resident on a device. To this end, a markup language file is created. The markup language file has a representation of information used to setup the remote control application to communicate with an appliance. The markup language file may be executed, on the device or an intermediate client with which the device is synchronized, to upload the representation of the information to a remote server. At the remote server, the uploaded information is used to automatically display user-selectable, downloadable data files relevant to the control of the appliance. Downloaded data files, which may include command codes and/or graphical user interface elements, may be used within the device to upgrade the ability of the remote control application to communicate with the appliance. The information uploaded to the server may also be used to generate demographic data regarding consumer preferences.

Abstract: A remote control for communicating commands to a target device having first data that specifies a function supported by the target device. The remote control includes a set of command key indicias, stored within the universal remote control prior to any communications with the target device, each command key indicia being assigned a function identifier. The remote control is adapted to receive the first data from the target device and select a command key indicia from the set of command key indicias that has a function identifier that corresponds to the function specified by the first data. The selected command key indicia is displayable on a display of the universal remote control in association with a command key actuatable to communicate one or more commands to the target device to control the function supported by the target device that is represented by the first data.