Abstract: Methods and compositions are described for categorizing and treating autoimmune disease, using single cell network profiling (SCNP), where activation levels of one or more activatable elements are determined in single cells, with or without modulation, to categorize or determine treatment for the autoimmune disease.

Abstract: Methods and compositions are described for categorizing and treating autoimmune disease, using single cell network profiling (SCNP), where activation levels of one or more activatable elements are determined in single cells, with or without modulation, to categorize or determine treatment for the autoimmune disease.

Abstract: A combination screening apparatus and carrier. The screening apparatus has three hydraulic leg assemblies which are adapted to lift and lower the screening apparatus off and onto a carrier. The legs are positioned and operable that a carrier may be slid directly under the screening apparatus without interference with the legs. The carrier has pivotable holding elements which engage grasping elements fixedly attached to said screening apparatus. The shape and configuration of the holding elements and grasping elements are such that the screening apparatus is self-aligning on the carrier. The carrier may be left under the screening apparatus or removed during screening operations.