Patents by Inventor James Crapo

James Crapo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted Porphyrins
    Publication number: 20080113956
    Abstract: The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating cellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods.
    Type: Application
    Filed: January 17, 2008
    Publication date: May 15, 2008
    Inventors: Irwin Fridovich, Ines Batinic-Haberle, James Crapo, Brian Day
  • OXIDANT SCAVENGERS FOR TREATMENT OF DIABETES OR USE IN TRANSPLANTATION OR INDUCTION OF IMMUNE TOLERANCE
    Publication number: 20080085883
    Abstract: The present invention relates, in one embodiment, to a method of preventing or treating diabetes using low molecular weight antioxidants. In a further embodiment, the invention relates to a method of protecting and/or enhancing viability of cells/tissues/organs during isolation (harvesting), preservation, expansion and/or transplantation. In yet another embodiment, the present invention relates to a method of inducing immune tolerance. The invention also relates to compounds and compositions suitable for use in such methods.
    Type: Application
    Filed: September 19, 2007
    Publication date: April 10, 2008
    Applicants: AEOLUS SCIENCES, INC., National Jewish Medical and Research Center, University of Colorado Health Sciences Center, Children's Hospital of Pittsburgh
    Inventors: Jon PIGANELLI, Kathryn HASKINS, Sonia FLORES, James CRAPO, Brian DAY, Ronald GILL, Richard GAMMANS, Manisha PATEL
  • SUBSTITUTED PORPHYRINS
    Publication number: 20070197496
    Abstract: The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating cellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods.
    Type: Application
    Filed: June 16, 2006
    Publication date: August 23, 2007
    Inventors: James Crapo, Brian Day, Michael Trova, Polvina Gauuan, Douglas Kitchen, Irwin Fridovich, Ines Batinic-Haberle
  • Substituted Porphyrins
    Publication number: 20070179124
    Abstract: The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating cellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods.
    Type: Application
    Filed: September 15, 2006
    Publication date: August 2, 2007
    Inventors: Irwin Fridovich, Ines Batinic-Haberle, James Crapo, Brian Day
  • CANCER THERAPY
    Publication number: 20070149498
    Abstract: The present invention relates, in general, to cancer therapy, and, in particular, to a method of preventing or treating cancer using low molecular weight antioxidants (e.g., mimetics of superoxide dismutase (SOD)) as the active agent or as a chemo- and/or radio-protectant. The invention also relates to compounds and compositions suitable for use in such a method.
    Type: Application
    Filed: November 9, 2006
    Publication date: June 28, 2007
    Applicants: Aeolus Sciences, Inc., National Jewish Medical and Research Center, Duke University
    Inventors: James Crapo, Brian Day, Ines Batinic-Haberle, Richard Gammans, Zeljko Vusjaskovic
  • Substituted porphyrins
    Publication number: 20060074062
    Abstract: The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating cellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods.
    Type: Application
    Filed: May 12, 2005
    Publication date: April 6, 2006
    Applicants: DUKE UNIVERSITY, NATIONAL JEWISH MEDICAL AND RESEARCH CENTER
    Inventors: Irwin Fridovich, Ines Batinic-Haberle, James Crapo, Brian Day