Abstract: A system and method for robotic interfacing is provided herein. The robotic system includes a payload interface comprising a platform side and a receptacle side. The platform side is robotically maneuverable, and adaptable to carry a payload. The receptacle side is affixed to a host structure. The payload interface is autonomously removed and replaced by a robotic manipulator. The robotic manipulator includes an end effector having a grapple mechanism that connects with a grapple fixture of the platform side.

Abstract: An improved packing efficiency of helical tube bundles in a heat exchanger is achieved by positioning three 3-tube bundles, two twisted in one direction and the third twisted in the opposite direction, and selecting the angular orientation of the tube bundles so as to allow them to nest together in phase so that peaks of adjacent tube bundles are located between each other, forming a bundle overlap. An exemplary application is an EGR cooler.

Abstract: Systems and methods for automated cell culturing are disclosed. In some embodiments, one or more cell culture vessels are fluidly connected with one or more multiport valves and one or more fluid pumps. The fluid pumps may pump various fluids into and out of the cell culture vessels as necessary to support cell growth, routed by the one or more multiport valves. In some embodiments, one or more components may be removable from other components so that some components may be prepared and sterilized independently prior to usage.

Abstract: Systems and methods for automated cell culturing are disclosed. In some embodiments, one or more cell culture vessels are fluidly connected with one or more multiport valves and one or more fluid pumps. The fluid pumps may pump various fluids into and out of the cell culture vessels as necessary to support cell growth, routed by the one or more multiport valves. In some embodiments, one or more components may be removable from other components so that some components may be prepared and sterilized independently prior to usage.

Abstract: Formulations, methods, and kits comprising at least one Clostridium toxin derivative and at least one chemical depolarizing agent suitable for inducing local, partial or complete muscle paralysis or muscle denervation in a subject are described.

Abstract: An improved packing efficiency of helical tube bundles of the same twist in a heat exchanger is achieved by selecting the angular orientation of the tube bundles so as to allow them to nest together in phase so that peaks of adjacent tube bundles are located between each other, forming a bundle overlap. An exemplary application is an EGR cooler.

Abstract: The method and system are directed at providing group purchasing at a historical price in an e-commerce environment. A user may select a price that a price at which a produce previous sold, seen as the historical price. This price may then be used to generate an online purchasing campaign that other user may join. The purchasing campaign is user or consumer driver rather than merchant driven.

Abstract: Pharmaceutical compositions that extend the effect and duration of a Clostridial toxin active ingredient are described. The compositions can be liquid or solid compositions, and comprise a non-cross-linked hyaluronic acid or salt thereof as described in the application, a surfactant and an antioxidant. In some embodiments, the compositions comprise a surfactant selected from a poloxamer and a polysorbate; an antioxidant selected from methionine. N-acetyl cysteine, ethylenediaminetetraacetic acid and combinations thereof, and, optionally, a tonicity agent and/or a lyoprotector selected from, for example, trehalose, sucrose.

Abstract: Systems and methods for automated cell culturing are disclosed. In some embodiments, one or more cell culture vessels are fluidly connected with one or more multiport valves and one or more fluid pumps. The fluid pumps may pump various fluids into and out of the cell culture vessels as necessary to support cell growth, routed by the one or more multiport valves. In some embodiments, one or more components may be removable from other components so that some components may be prepared and sterilized independently prior to usage.

Abstract: An onboard washing system provides the ability to wash specific areas at the rear of a concrete truck, without requiring an operator to climb a ladder or climb on the truck. Certain specified areas which are traditionally difficult to wash, including the inside of the charge hopper, the interior portions of the discharge chute, and rear portions of the mixing drum structure, can now be washed in an automated and efficient manner. The truck-mounted washing system has components which are specifically positioned to cause washing fluid (water) to be sprayed or directed toward predetermined areas in an efficient and effective manner. The system also includes hand-held washing wands or washing mechanisms, which allow an operator to easily reach additional zones or additional areas at the rear of the truck, which are lower. Most significantly, the truck-mounted wash systems and the hand-held nozzle systems (wand) are all operable while an operator remains on the ground.

Abstract: Formulations, methods, and kits comprising at least one Clostridium toxin derivative and at least one chemical depolarizing agent suitable for inducing local, partial or complete muscle paralysis or muscle denervation in a subject are described.

Abstract: A delivery chute for use on a concrete mixer truck has automated systems to allow for repositioning and reconfiguration without requiring an operator to manipulate components. The chute is configured to have multiple segments that can be folded/nested with one another for transport and can be positioned in an extended configuration thereby forming a continuous delivery surface for purposes of delivering concrete to a desired location. Powered mechanisms are used to reposition these segments, thus eliminating the need for operators to handle chute segments at all. A control system is provided to coordinate operation of components so proper sequences are followed during folding, unfolding, raising, lowering and swinging operations. An operator can control each of these operations using a remote control, having single buttons to carry out specific operations.

Abstract: Systems and methods for automated cell culturing are disclosed. In some embodiments, one or more cell culture vessels are fluidly connected with one or more multiport valves and one or more fluid pumps. The fluid pumps may pump various fluids into and out of the cell culture vessels as necessary to support cell growth, routed by the one or more multiport valves. In some embodiments, one or more components may be removable from other components so that some components may be prepared and sterilized independently prior to usage.

Abstract: The method and system are directed at providing group purchasing at a historical price in an e-commerce environment. A user may select a price that a price at which a produce previous sold, seen as the historical price. This price may then be used to generate an online purchasing campaign that other user may join. The purchasing campaign is user or consumer driver rather than merchant driven.

Abstract: Disclosed herein are compounds having a structure of formula (I), compositions and methods useful for the treatment of a disease or infection, such as a viral infection (e.g.

Abstract: An onboard washing system provides the ability to wash specific areas at the rear of a concrete truck, without requiring an operator to climb a ladder or climb on the truck. Certain specified areas which are traditionally difficult to wash, including the inside of the charge hopper, the interior portions of the discharge chute, and rear portions of the mixing drum structure, can now be washed in an automated and efficient manner. The truck-mounted washing system has components which are specifically positioned to cause washing fluid (water) to be sprayed or directed toward predetermined areas in an efficient and effective manner. The system also includes hand-held washing wands or washing mechanisms, which allow an operator to easily reach additional zones or additional areas at the rear of the truck, which are lower. Most significantly, the truck-mounted wash systems and the hand-held nozzle systems (wand) are all operable while an operator remains on the ground.

Abstract: Systems and methods for automated cell culturing are disclosed. In some embodiments, one or more cell culture vessels are fluidly connected with one or more multiport valves and one or more fluid pumps. The fluid pumps may pump various fluids into and out of the cell culture vessels as necessary to support cell growth, routed by the one or more multiport valves. In some embodiments, one or more components may be removable from other components so that some components may be prepared and sterilized independently prior to usage.

Abstract: In one embodiment, a gateway includes a memory, and a processor to, in response to receiving a plurality of content requests, generate a plurality of network flows and flow buffers, each one content request of the plurality of content requests being served by one network flow of the plurality of network flows, and one flow buffer of the plurality of flow buffers, the one flow buffer being included in the memory, the plurality of network flows including a first flow and a second flow, the first flow serving one of the plurality of requests having a first priority level, the second flow serving one of the plurality of requests having a second priority level, the first priority level being higher than the second priority level, and run a network arbiter to give prioritize reading the first flow over reading the second flow when the first flow is non-idle.

Abstract: Client-side Quality-of-Service (QoS) for viewing of Adaptive Bitrate (ABR) streams may be provided. First, a plurality of Adaptive Bitrate (ABR) objects corresponding to a first video rendition of a content program may be downloaded from a Content Delivery Network (CDN) in non-real-time. The plurality of ABR objects may comprise a portion of ABR objects comprising the content program. Next, the plurality of ABR objects downloaded in non-real-time may be stored in a cache. At least a portion of the content program may then be retrieved in real-time using ABR streaming. Retrieving the at least a portion of the content program may comprise obtaining a first ABR object corresponding to the content program and a second ABR object corresponding to the content program.

Abstract: A method and system for providing automated on-site merchant coupons including determining a product of interest, determining if there is a coupon available for the product of interest and then generating and transmitting the coupon if one is available. The determination of whether a coupon is available may be based on a set of rules as designated by a merchant or may be based on a price-matching criteria.