Patents by Inventor James D. Jowett

James D. Jowett has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Host cells and methods of use
    Patent number: 10392625
    Abstract: The present invention provides genetically modified Pichia strains wherein at least one nucleic acid sequence encoding a functional gene product and/or at least one nucleic acid sequence necessary for expression of at least one functional gene product in said Pichia strain is genetically modified, wherein said gene product is responsible for proteolysis and/or glycosylation in said genetically modified Pichia strain. In particular, Pichia strains are provided wherein nucleic acid sequence encoding a functional gene product or expression of said gene product are genetically modified: PEP4, PRB1, YPS1, YPS2, YMP1, YMP2, YMP3 and PMT4.
    Type: Grant
    Filed: February 24, 2010
    Date of Patent: August 27, 2019
    Assignee: GlaxoSmithKline LLC
    Inventors: Yong Hwan Jin, James D. Jowett, Alexander H. Taylor, Yuan Zhu
  • HOST CELLS AND METHODS OF USE
    Publication number: 20120142895
    Abstract: The present invention provides genetically modified Pichia strains wherein at least one nucleic acid sequence encoding a functional gene product and/or at least one nucleic acid sequence necessary for expression of at least one functional gene product in said Pichia strain is genetically modified, wherein said gene product is responsible for proteolysis and/or glycosylation in said genetically modified Pichia strain. In particular, Pichia strains are provided wherein nucleic acid sequence encoding a functional gene product or expression of said gene product are genetically modified: PEP4, PRB1, YPS1, YPS2, YMP1, YMP2, YMP3 and PMT4.
    Type: Application
    Filed: February 24, 2010
    Publication date: June 7, 2012
    Inventors: Yong Hwan Jin, James D. Jowett, Alexander H. Taylor, Yuan Zhu