Patents by Inventor James D. KOROPATNICK

James D. KOROPATNICK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING CANCER BY INHIBITION OF DNA REPAIR PROTEINS USING ANTISENSE BASED THERAPIES
    Publication number: 20190002884
    Abstract: Methods of treating cancer using antisense based therapies including antisense oligonucleotides of si RNAs directed against DNA double-strand break repair proteins such as BRCA2 or RAD51 are provided. The antisense based therapies can be used alone, in tandem or in combination with other cancer therapies, in particular with therapies that lead to DNA damage, inhibition of DNA repair or inhibition of DNA synthesis, such as radiation, platinum drugs, alkylating agents, PARP inhibitors, or inhibitors of thymidylate synthase.
    Type: Application
    Filed: December 16, 2016
    Publication date: January 3, 2019
    Inventors: Mark D. VINCENT, Peter FERGUSON, James D. KOROPATNICK, Mateusz RYTELEWSKI