Abstract: A tissue treatment system and method of using the tissue treatment system determines a size of a body lumen, or a neuromodulation parameter corresponding to the size of the body lumen. The tissue treatment system fills a balloon with a fluid when the balloon is within a body lumen. A fluid parameter of the fluid is detected over a period of time. A parameter curve of the fluid parameter is determined. The parameter curve includes the fluid parameter versus an independent variable over the period of time. The system compares the parameter curve of the fluid parameter to a reference curve and, based on the comparison, determine the body lumen size or the neuromodulation parameter. Other embodiments are also described and claimed.

Abstract: A tissue treatment system and method of using the tissue treatment system determines a size of a body lumen, or a neuromodulation parameter corresponding to the size of the body lumen. The tissue treatment system fills a balloon with a fluid when the balloon is within a body lumen. A fluid parameter of the fluid is detected over a period of time. A parameter curve of the fluid parameter is determined. The parameter curve includes the fluid parameter versus an independent variable over the period of time. The parameter curve includes inflections that correspond to changes in the fluid parameter. Based on the inflections, the system can determine the body lumen size or the neuromodulation parameter. Other embodiments are also described and claimed.

Abstract: A catheter has at least a first transducer located in an interior of at least a first balloon, the first transducer configured to be operated at an operational frequency.

Abstract: A catheter comprises a catheter shaft having a fluid channel, an ultrasound transducer and a compliant balloon mounted on the catheter shaft and having an interior in fluid communication with the fluid channel and containing the ultrasound transducer. The compliant balloon includes a balloon wall having a working section radially surrounding the ultrasound transducer. The working section has a predetermined straightness when the working section has a first diameter and when the working section has a second diameter that is at least 2 mm greater than the first diameter. Other embodiments are also described and claimed.

Abstract: A treatment system includes a generator and a fluid transfer cartridge. The fluid transfer cartridge includes a cartridge shell defining a cartridge cavity between a front face and a rear face. The front face includes an opening, and the cartridge cavity is visibly exposed through the opening. The fluid transfer cartridge includes a syringe barrel disposed within the cartridge cavity, and a handle that extends from the front face over the opening. The syringe barrel can be visibly exposed on a side of the handle. Other embodiments are also described and claimed.

Abstract: A treatment system includes a generator and a fluid transfer cartridge. The fluid transfer cartridge includes a cartridge shell having a cartridge cavity. The cartridge cavity is between a front face and a rear face. A syringe barrel is disposed within the cartridge cavity, and has a syringe cavity. The fluid transfer cartridge includes a cartridge manifold in the cartridge cavity. The cartridge manifold includes a fluid transfer plate having a front fluid channel in a front plate surface, and a rear fluid channel in a rear plate surface. The cartridge manifold includes a fluid port extending through the fluid transfer plate from the front fluid channel to the rear fluid channel. The front fluid channel, the rear fluid channel, and the fluid port are in fluid communication with the syringe cavity. Other embodiments are also described and claimed.

Abstract: A tissue treatment catheter and system include a catheter shaft sized and shaped for delivery through a radial artery to a blood vessel of a patient. The catheter shaft has several lumens, including a guidewire lumen, a cable lumen, and one or more fluid lumens. A stiffening web extends from the guidewire lumen and is thicker than an outer wall of the catheter shaft. The tissue treatment catheter and system include an ultrasound transducer, a balloon surrounding the ultrasound transducer, and a single electrical cable electrically connected to the ultrasound transducer to deliver sufficient electrical energy during sonication to the transducer such that the transducer thermally induces modulation of neural fibers surrounding the blood vessel sufficient to improve a measurable physiological parameter corresponding to a diagnosed condition of the patient. Other embodiments are described and claimed.

Abstract: Described herein are acoustic-based tissue treatment systems, apparatuses, and methods for use therewith. Certain such apparatuses comprise a catheter sized and shaped for delivery through a radial artery including a catheter shaft having distal and proximal ends, a plurality of lumens extending longitudinally through the catheter shaft between the distal and proximal ends thereof, and an ultrasound transducer distally positioned relative to the distal end of the catheter shaft. A balloon may surround the ultrasound transducer and at least one of the plurality of lumens may be configured to provide a cooling fluid to the balloon at a pressure and flow rate sufficient to protect non-target tissue in the blood vessel wall from thermal injury.

Abstract: The present disclosure includes devices, systems and related methods useable for controlling a patient's body temperature by endovascular heat exchange as well as body surface heat exchange.

Abstract: The present disclosure includes devices, systems and related methods useable for controlling a patient's body temperature by endovascular heat exchange as well as body surface heat exchange.

Abstract: Disclosure includes fluid-circulating heat exchange catheters, systems and related methods useable for controlling a patient's body temperature.

Abstract: Disclosure includes fluid-circulating heat exchange catheters, systems and related methods useable for controlling a patient's body temperature.

Abstract: Disclosure includes fluid-circulating heat exchange catheters, systems and related methods useable for controlling a patient's body temperature.

Abstract: Disclosure includes fluid-circulating heat exchange catheters, systems and related methods useable for controlling a patient's body temperature.

Abstract: The present disclosure includes devices, systems and related methods useable for controlling a patient's body temperature by endovascular heat exchange as well as body surface heat exchange.

Abstract: Disclosure includes fluid-circulating heat exchange catheters, systems and related methods useable for controlling a patient's body temperature.

Abstract: Disclosure includes fluid-circulating heat exchange catheters, systems and related methods useable for controlling a patient's body temperature.