Patents by Inventor James D. Rodgers

James D. Rodgers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indazoles of cyclic ureas useful as HIV protease inhibitors
    Patent number: 5985867
    Abstract: The present invention describes indazoles of cyclic ureas of formula I: ##STR1## wherein X is a linker group and Y may be acyclic or cyclic, which are useful as inhibitors of HIV protease, and pharmaceutical compositions and diagnostic kits comprising the same.
    Type: Grant
    Filed: March 30, 1998
    Date of Patent: November 16, 1999
    Assignee: DuPont Pharmaceuticals Company
    Inventors: James D. Rodgers, Barry L. Johnson, Haisheng Wang
  • Substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors
    Patent number: 5610294
    Abstract: This invention relates to substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors, to pharmaceutical compositions comprising such compounds, and to methods of using these compounds for treating viral infection. A representative compound of the invention is the compound of formula: ##STR1## wherein R.sup.22 and R.sup.23 are allyl.
    Type: Grant
    Filed: February 16, 1994
    Date of Patent: March 11, 1997
    Assignee: The Du Pont Merck Pharmaceutical Company
    Inventors: Patrick Y. Lam, Prabhakar K. Jadhav, Charles J. Eyermann, Carl N. Hodge, George V. De Lucca, James D. Rodgers
  • Method for preparing N-monosubstituted and N,N'-disubstituted unsymmetrical cyclic ureas
    Patent number: 5532357
    Abstract: The present invention relates generally to methods for the preparation of unsymmetrically substituted cyclic ureas of the formulae ##STR1## which are useful as HIV protease inhibitors. The methods provided go through an isourea intermediate.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 2, 1996
    Assignee: The DuPont Merck Pharmaceutical Company
    Inventors: James D. Rodgers, Jung-Hui Sun
  • Preparation of cyclic urea compounds
    Patent number: 5508400
    Abstract: This invention relates to the preparation of cyclic urea compounds. More specifically, this invention is directed to methods for selectively alkylating diamines, methods for selectively converting a mixture of alkylated and non-alkylated diamines to cyclic urea compounds, methods to purify cyclic urea compounds having a single N-substitution, methods to convert a cyclic urea compound having a single N-substitution to a cyclic urea compound having either symmetrical or non-symmetrical N,N'-disubstitution, and methods to remove protecting groups from cyclic urea compounds.
    Type: Grant
    Filed: April 20, 1994
    Date of Patent: April 16, 1996
    Assignee: The Du Pont Merck Pharmaceutical Company
    Inventors: Wendell W. Wilkerson, James D. Rodgers
  • Process for producing 1-(5-substituted-2-ethynylphenyl)-2-propanones
    Patent number: 4798893
    Abstract: A method for the synthesis of the 2-propanone (I) is described starting from alkoxide (II) through the lactone (IV). ##STR1## Excellent control of the location of the substitution on the phenyl ring is achieved and the reaction proceeds in high yield.
    Type: Grant
    Filed: September 21, 1987
    Date of Patent: January 17, 1989
    Assignee: McNeilab, Inc.
    Inventors: David A. Cherry, Cynthia A. Maryanoff, John E. Mills, Roy A. Olofson, James D. Rodgers
  • Kelly spinner
    Patent number: 4485697
    Abstract: A kelly spinner rotatable in opposite directions in which means are provided for preventing engagement of the jaws of the spinner with the pipe when rotated in one direction by a stop which may be removed by the operator to permit the jaws to engage when rotated in said direction.
    Type: Grant
    Filed: April 29, 1983
    Date of Patent: December 4, 1984
    Assignee: Foster Cathead Company
    Inventors: Joe K. Heilhecker, James D. Rodgers, Steven C. Gaare