Abstract: A method and system for separating valuable material, such as precious metals and rare earth elements, from a raw material, such as coal, is disclosed. The system may include a crusher or pulverizer for producing finely crushed material. This crushed material may be made into a slurry and placed into an econosizer for separating material by its specific gravity. High specific gravity material may be further refined using magnets, separators, or centrifuges, among other disclosed components of the system.

Abstract: Systems and methods for monitoring and managing versioning changes to computational workflows caused by ongoing development of computational modules implemented within the computational workflows. Exemplary implementations may: store a workflow repository and a user repository; monitor the workflow repository to detect changes to computational modules included in the workflow repository; responsive to detections of changes to the computational modules, identify computational workflows defined by workflow definitions impacted by the detected changes; identify, based on information included in the user repository, users associated with the identified computational workflows; manage information defining user interfaces associated with individual users; update information defining the user interfaces based on the detected changes and the identified users; effectuate presentation of the user interfaces to the users; and/or other exemplary implementations.

Abstract: The following disclosure relates to electrolysis systems having an electrolysis cell stack and a fluids processing system (e.g., an oxygen and water gas separator). In certain examples, a portion of the fluids processing system is configured to operate at a reduced (lower) pressure than the electrolysis cell stack within the electrochemical processing system through the use of a recovery turbine positioned between the electrolysis cell stack and the oxygen and water gas separator along a fluids transfer line, wherein the recovery turbine is configured to reduce a pressure within the fluids transfer line from an elevated pressure at the electrolysis cell stack to the lower pressure at the separator.

Abstract: The invention provides a compound of formula (1). or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.

Abstract: Systems, media, and methods for automated response to social queries comprising: monitoring queries from users, each query submitted to a vendor via an interactive chat feature of an external electronic communication platform, monitoring human responses to the queries, monitoring subsequent communications conducted via the electronic communication platform until each query is resolved; applying a first machine learning algorithm to the monitored communications to identify a query susceptible to response automation; applying a second machine learning algorithm to the query susceptible to response automation to identify one or more responses likely to resolve the query; and either i) notifying a human to respond to the query susceptible to response automation with the one or more responses likely to resolve the query, or ii) instantiating an autonomous software agent configured to respond to the query susceptible to response automation with the one or more responses likely to resolve the query.

Abstract: The invention relates to processes for preparing isoindolin-1-one derivatives, and in particular processes for preparing (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid. The invention also relates to crystalline forms of the compound (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid and its salts.

Abstract: Methods of forming an optical fiber assembly involve placing an adhesive in a ferrule assembly, heating the ferrule assembly through thermal induction, inserting an optical fiber into the ferrule bore during or after the heating step, and securing the optical fiber to the ferrule assembly using the adhesive. The thermal induction causes the adhesive to efficiently take or maintain a melted form to allow the optical fiber insertion.

Abstract: A side view mirror assembly includes a base frame configured to couple to a bracket that is connected to a vehicle static structure. The base frame interfacing with the bracket through a guide that is at least partially received within a pocket when the base frame is coupled to the bracket. A mirror housing assembly is adjustably supported by the base frame.

Abstract: A magnetic and modular serving board is described. The magnetic and modular serving board includes a multitude of an individual sidewall, the sidewall having an inner surface and an outer surface. The individual sidewall is connected together to form a connected sidewall in a polygon shape. The inner perimeter of the connected sidewalls forms a recessed area. A magnet is attached to the outer surface of each individual sidewall. The magnet is arranged along the outer perimeter of the connected sidewalls such that a polarity of one magnet is different from the polarity of the attached magnet of the immediate adjacent sidewall. The magnetic and modular serving board also includes a base extending from a bottom surface. The base matches the polygon shape of the connected walls and sits within the recessed area and inner perimeter of another magnetic and modular serving board.

Abstract: A system and method for phase and gain calibration of a current sensor system. The system comprises a microcontroller configured to execute software in an energy measurement component and a calibration computer having a calibration application. The energy measurement component receives first and second digital signals representing current and voltage signals, respectively, received from a test source, and calculates active power and a power factor, and provides those values to the calibration computer. The power factor is converted to a converted phase angle. Based on the information received from the energy measurement component, the calibration application calculates parameters used to update components within the microcontroller to maximize the accuracy of the current sensor system.

Abstract: A wearable fishing pole holding device includes an elongated tubular-shaped main body having a top end, a closed bottom end and a hollow interior. A neck strap extends outward from a top portion of the main body for positioning the main body against the chest of a user, and a belt loop extends outward from the bottom end of the main body for engaging the belt of a user. A malleable lip extends downward from the main body and is positionable between a users waist and belt. The belt loop and lip secure the bottom portion of the main body against the users waist. The main body includes an opening along the top end for receiving the bottom end of a fishing pole. Semi-circular indentations hold a reel secured to the fishing pole in place to permit one handed operation of the reel.

Abstract: The invention relates to a ceramic feedstock comprising the components a), b) and optionally c), wherein component a) is at least one ceramic material, component b) is at least one binder (B) and optional component c) is at least one additive (A). The ceramic feedstock is preferably provided in form of a filament to be employed in three-dimensional (3D) printing techniques, particularly in a FFF printing process. The inventive ceramic feedstock can, therefore, be successfully employed for the 3D printing of support structures and/or separation layers. Further, the invention also relates to three-dimensional objects as such, in particular three-dimensional green bodies, three-dimensional brown bodies or three-dimensional sintered bodies as well as to a process for the preparation thereof.

Abstract: An exhaled breath condensate (EBC) collector for converting breath vapor received from the lungs and airways of a test subject into an EBC fluid biosample. The EBC collector including a cooling system for cooling a condensing surface wherein the breath vapor is coalesced into liquid droplets forming the EBC fluid sample. A biomarker concentrator concentrates a target biomarker portion in the fluid biosample to form a concentrated fluid biosample. The biomarker concentrator comprises a selectively permeable barrier for allowing excess water in the fluid biosample to pass through the selectively permeable barrier and block the target biomarker in the fluid biosample from passing through the selectively permeable barrier. A biomarker testing unit receives the concentrated fluid biosample and tests the concentrated fluid biosample for the target biomarker.

Abstract: Wnt signaling agonist compositions and methods for their use are provided. Wnt signaling agonists of the invention comprise a frizzled binding moiety, which is fused or conjugated to an LRP5 or LRP6 binding moiety.

Abstract: Methods and systems for securing endpoint devices are disclosed. Overtime, the functionality of endpoint devices may be modified as new software is developed. To secure endpoint devices, software images of the new software may be verified prior to execution. Information usable to verify the software images may be stored in a database. A set of rules may be used to verify the trustworthiness of the software images based on the content of the database. Another set of rules may be used to verify the content of the database.

Abstract: Methods of forming an optical fiber assembly involve placing an adhesive in a ferrule assembly, heating the ferrule assembly through thermal induction, inserting an optical fiber into the ferrule bore during or after the heating step, and securing the optical fiber to the ferrule assembly using the adhesive. The thermal induction causes the adhesive to efficiently take or maintain a melted form to allow the optical fiber insertion.

Abstract: A method and system for separating valuable material, such as precious metals and rare earth elements, from a raw material, such as coal, is disclosed. The system may include a crusher or pulverizer for producing finely crushed material. This crushed material may be made into a slurry and placed into an econosizer for separating material by its specific gravity. High specific gravity material may be further refined using magnets, separators, or centrifuges, among other disclosed components of the system.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer-storage media, for a lighting controller for sea lice detection. In some implementations, fish are contained within an elliptical tank filled with water. An imaging station located on the elliptical tank is used to capture an image of a fish from which image analysis can be performed to detect sea lice or other skin features, including lesions, on the fish. Pairs of imaging assemblies coordinate pulsing light of at least a first and a second color and capturing images of the fish while the fish is illuminated by at least the first and the second color. By using the captured images with different color light, computers can detect features on the body of a fish including sea lice, skin lesions, shortened operculum or other physical deformities and skin features. Detection results can aid in mitigation techniques or be stored for analytics.

Abstract: The following disclosure relates to a system and method of actively managing electrolyzer stack compression. The method includes receiving, by a data acquisition unit, stack data from an electrolyzer stack in real time; providing, by the data acquisition unit, the stack data to a compression force controller; and controlling, by the compression force controller, when and how much force is applied by a force generating mechanism to the electrolyzer stack based on the stack data.

Abstract: The present invention relates to novel cyclic peptide inhibitors of the interleukin-23 receptor (IL-23R) or pharmaceutically acceptable salt thereof, corresponding pharmaceutical compositions, methods and/or uses for treatment of autoimmune inflammation and related diseases and disorders. The inhibitor of an interleukin-23 receptor is cyclized by a disulfide bond between penicillamine, cysteine, homocysteine, or alpha methylcysteine residues at positions X4 and X9.