Patents by Inventor James Daniel Allen

James Daniel Allen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12161712
    Abstract: Provided herein are non-naturally occurring, broadly reactive, pan-epitopic antigens derived from H3 influenza virus that are immunogenic and are capable of eliciting a broadly reactive immune response, such as a broadly reactive neutralizing antibody response, against H3 virus following introduction into a subject. Also provided are non-naturally, broadly reactive occurring immunogens, vaccines, virus-like particles (VLPs) and compositions comprising the immunogens and vaccines. Methods of generating an immune response in a subject by administering the immunogens, vaccines, VLPs, or compositions thereof are provided. In particular, the immunogens comprise the hemagglutinin (HA) protein of H3 influenza virus strains.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: December 10, 2024
    Assignee: University of Georgia Research Foundation
    Inventors: James Daniel Allen, Ted Milburn Ross, Terianne Maiko Wong
  • Publication number: 20240148851
    Abstract: Provided herein are non-naturally occurring, broadly reactive, pan-epitopic antigens derived from Dengue virus that are immunogenic and elicit a broadly reactive immune response, such as a broadly reactive neutralizing antibody response, against Dengue virus subtypes following introduction into a subject. Also provided are non-naturally, broadly reactive occurring immunogens, immunogenic compositions, vaccines, subviral particles (SVPs), and virus-like particles (VLPs) comprising Dengue virus proteins or encoding polynucleotides. Methods of generating an immune response in a subject by administering the immunogens, vaccines, SVPs, VLPs, or immunogenic compositions thereof are provided. In particular, the immunogens comprise a Dengue virus protein, or an antibody binding portion thereof.
    Type: Application
    Filed: June 6, 2023
    Publication date: May 9, 2024
    Applicant: University of Georgia Research Foundation, Inc.
    Inventors: James Daniel ALLEN, Maria Teresa AREVALO, Ted Milburn ROSS, Naoko UNO, Terianne Maiko WONG
  • Publication number: 20220001001
    Abstract: Provided herein are non-naturally occurring, broadly reactive, pan-epitopic antigens derived from Dengue virus that are immunogenic and elicit a broadly reactive immune response, such as a broadly reactive neutralizing antibody response, against Dengue virus subtypes following introduction into a subject. Also provided are non-naturally, broadly reactive occurring immunogens, immunogenic compositions, vaccines, subviral particles (SVPs), and virus-like particles (VLPs) comprising Dengue virus proteins or encoding polynucleotides. Methods of generating an immune response in a subject by administering the immunogens, vaccines, SVPs, VLPs, or immunogenic compositions thereof are provided. In particular, the immunogens comprise a Dengue virus protein, or an antibody binding portion thereof.
    Type: Application
    Filed: July 12, 2019
    Publication date: January 6, 2022
    Applicant: University of Georgia Research Foundation
    Inventors: James Daniel Allen, Maria Teresa Arevalo, Ted Milburn Ross, Naoko Uno, Terianne Maiko Wong
  • Publication number: 20210379180
    Abstract: Provided herein are non-naturally occurring, broadly reactive, pan-epitopic antigens derived from H3 influenza virus that are immunogenic and are capable of eliciting a broadly reactive immune response, such as a broadly reactive neutralizing antibody response, against H3 vims following introduction into a subject. Also provided are non-naturally, broadly reactive occurring immunogens, vaccines, virus-like particles (VLPs) and compositions comprising the immunogens and vaccines. Methods of generating an immune response in a subject by administering the immunogens, vaccines, VLPs, or compositions thereof are provided. In particular, the immunogens comprise the hemagglutinin (HA) protein of H3 influenza vims strains.
    Type: Application
    Filed: July 12, 2019
    Publication date: December 9, 2021
    Applicant: University of Georgia Research Foundation
    Inventors: James Daniel Allen, Ted Milburn Ross, Terianne Maiko Wong
  • Publication number: 20210327533
    Abstract: Provided herein are methods for generating a non-naturally occurring, broadly reactive, pan-epitopic antigen derived from a pathogen, such as a virus, bacterium, and the like, that is immunogenic and is capable of eliciting a broadly reactive immune response, such as a broadly reactive neutralizing antibody response, against the pathogen following introduction into a subject. Also provided is a non-naturally occurring immunogen generated using the methods, and vaccines and compositions comprising the immunogen. Methods of generating an immune response in a subject by administering the immunogen, vaccine, or composition are provided. In particular, the immunogen comprises the hemagglutinin (HA) or neuraminidase (NA) protein of influenza virus strains.
    Type: Application
    Filed: July 12, 2019
    Publication date: October 21, 2021
    Applicant: University of Georgia Research Foundation
    Inventors: James Daniel Allen, Ted Milburn Ross, Terianne Maiko Wong, Anne Gaelle Bebin Blackwell, Ivette Ariela Nunez, Zachary Beau Reneer, Ying Huang
  • Publication number: 20210225457
    Abstract: Provided herein are methods for generating a non-naturally occurring, broadly reactive, pan-epitopic antigen derived from H3 influenza virus that is capable of eliciting a broadly reactive immune response, such as a broadly reactive neutralizing antibody response, against H3 virus following administration to a subject. Also provided is a non-naturally occurring immunogen generated using the methods, and vaccines and compositions comprising the immunogen. Methods of generating an immune response in a subject by administering the immunogen, vaccine, or composition are provided. In particular, the immunogen comprises the hemagglutinin (HA) protein of H3 influenza vims strains.
    Type: Application
    Filed: July 12, 2019
    Publication date: July 22, 2021
    Applicant: University of Georgia Research Foundation
    Inventors: James Daniel Allen, Ted Milburn Ross, Terianne Maiko Wong