Abstract: Methods and apparatus to form biocompatible energization elements are described. In some embodiments, the methods and apparatus to form the biocompatible energization elements involve forming cavities comprising active cathode chemistry. The active elements of the cathode and anode are sealed with a laminate stack of biocompatible material. In some embodiments, a field of use for the methods and apparatus may include any biocompatible device or product that requires energization elements.

Abstract: This invention discloses methods and apparatuses for sealing and encapsulating components on and within a multi-piece insert. In some embodiments, an ophthalmic lens is cast molded from a silicone hydrogel and the component includes a sealed and encapsulated multi-piece insert portion.

Abstract: This invention discloses a device comprising multiple functional layers formed on substrates, wherein at least one functional layer comprises an electrical energy source. In some embodiments, the present invention includes an insert for incorporation into ophthalmic lenses that has been formed by the stacking of multiple functionalized layers.

Abstract: Wnt signaling agonist compositions and methods for their use are provided. Wnt signaling agonists of the invention comprise a frizzled binding moiety, which is fused or conjugated to an LRP5 or LRP6 binding moiety.

Abstract: The present invention provides for a disinfecting radiation base for working in conjunction with a storage case for an ophthalmic lens. The disinfecting radiation base provides disinfecting radiation for disinfecting an ophthalmic lens. The disinfecting radiation base may also include a processor and digital memory for automated functions associated with the base.

Abstract: The present invention provides for a disinfecting radiation base with a germicidal bulb for providing disinfecting radiation to a storage case for an ophthalmic lens, such as a contact lens. The disinfecting radiation base provides disinfecting radiation for disinfecting a contact lens. The disinfecting radiation base may also include a processor and digital memory for automated functions associated with the base.

Abstract: Methods and apparatus to form biocompatible energization elements are described. In some examples, the methods and apparatus to form the biocompatible energization elements involve forming pellets comprising active cathode chemistry. The active elements of the cathode and anode are sealed with a biocompatible material. In some examples, a field of use for the methods and apparatus may include any biocompatible device or product that requires energization elements.

Abstract: This invention discloses methods and apparatus for providing a variable optic insert into an ophthalmic lens. A liquid crystal layer may be used to provide a variable optic function and in some examples, an alignment layer for the liquid crystal layer may be patterned in a cycloidally dependent manner. The patterning may allow for a polarization dependent lens in some examples. An energy source is capable of powering the variable optic insert included within the ophthalmic lens. In some examples, an ophthalmic lens is cast-molded from a silicone hydrogel. The various ophthalmic lens entities may include electroactive liquid crystal layers to electrically control optical characteristics.

Abstract: Systems, media, and methods for automated response to social queries comprising: monitoring queries from users, each query submitted to a vendor via an interactive chat feature of an external electronic communication platform, monitoring human responses to the queries, monitoring subsequent communications conducted via the electronic communication platform until each query is resolved; applying a first machine learning algorithm to the monitored communications to identify a query susceptible to response automation; applying a second machine learning algorithm to the query susceptible to response automation to identify one or more responses likely to resolve the query; and either i) notifying a human to respond to the query susceptible to response automation with the one or more responses likely to resolve the query, or ii) instantiating an autonomous software agent configured to respond to the query susceptible to response automation with the one or more responses likely to resolve the query.

Abstract: The present invention relates generally to an arcuate liquid meniscus lens with a meniscus wall. Some specific embodiments include a liquid meniscus lens with a meniscus wall essentially in the shape of multiple segments of a frustum of a cone. Embodiments may also include a lens of suitable size and shape for inclusion in a contact lens.

Abstract: Methods and apparatus to form biocompatible energization elements are described. In some examples, the methods and apparatus to form the biocompatible energization elements involve forming cavities composing active cathode chemistry. The active elements of the cathode and anode are sealed with a biocompatible material. In some examples, a field of use for the methods and apparatus may include any biocompatible device or product that requires energization elements.

Abstract: Methods and apparatus to form biocompatible energization elements are described. In some embodiments, the methods and apparatus to form the biocompatible energization elements involve forming cavities comprising active cathode chemistry. The active elements of the cathode and anode are sealed with a laminate stack of biocompatible material. In some embodiments, a field of use for the methods and apparatus may include any biocompatible device or product that requires energization elements.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for providing a call to action at the end of a resource. In one aspect, a method includes receiving a request for media content to present on a user device, the request including a second request for third-party content to present with the media content, identifying, user device capabilities that describes information about system compatibility for the user device, determining third-party content to present with the media, the third-party content including a first presentation time duration indicative of a length of time the third-party content is presented, determining that an end cap is compatible with the user device and related to the third-party content, the end cap providing an interactive opportunity to request subsequent resources for the user device, and transmitting data to present the third-party content, the end cap, and the media.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for providing a call to action at the end of a resource. In one aspect, a method includes receiving a request for media content to present on a user device, the request including a second request for third-party content to present with the media content, identifying, user device capabilities that describes information about system compatibility for the user device, determining third-party content to present with the media, the third-party content including a first presentation time duration indicative of a length of time the third-party content is presented, determining that an end cap is compatible with the user device and related to the third-party content, the end cap providing an interactive opportunity to request subsequent resources for the user device, and transmitting data to present the third-party content, the end cap, and the media.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for providing a call to action at the end of a resource. In one aspect, a method includes receiving a request for media content to present on a user device, the request including a second request for third-party content to present with the media content, identifying, user device capabilities that describes information about system compatibility for the user device, determining third-party content to present with the media, the third-party content including a first presentation time duration indicative of a length of time the third-party content is presented, determining that an end cap is compatible with the user device and related to the third-party content, the end cap providing an interactive opportunity to request subsequent resources for the user device, and transmitting data to present the third-party content, the end cap, and the media.

Abstract: New methods for aging aluminum alloys having zinc and magnesium are disclosed. The methods may include first aging the aluminum alloy at a first temperature of from about 310° F. to 530° F. and for a first aging time of from 1 minute to 6 hours, and then second aging the aluminum alloy at a second temperature for a second aging time of at least 30 minutes, with the second temperature being lower than the first temperature.

Abstract: The present invention discloses a method of forming a multi-piece insert for an ophthalmic lens, comprising: forming a insert back curve piece; forming a insert front curve piece; depositing a conductive material onto one or both of the insert front curve piece and the insert back curve piece; attaching an electronic component to one or both of the insert front curve piece and the insert back curve pieces, wherein the attachment is made to the conductive material; placing a material to form a first upon a surface of either or both of the insert front curve piece and the insert back curve piece; and combining the insert back curve piece with the insert front curve piece to form a ophthalmic insert piece, wherein the combining causes the material to seal a cavity interior to the combination of the back curve piece and the front curve piece.

Abstract: Methods and apparatus to form biocompatible energization elements are described. In some embodiments, the methods and apparatus to form the biocompatible energization elements involve forming cavities comprising active cathode chemistry. The active elements of the cathode and anode are sealed with a laminate stack of biocompatible material. In some embodiments, a field of use for the methods and apparatus may include any biocompatible device or product that requires energization elements.

Abstract: A user-activity video signal can be received. The user-activity video signal can comprise a video capture characterizing a user's interaction with a software application on a client. The software application can have an interface display space on the client and the software application can execute on the client in operation with at least one remote backend computing system. Backend user interaction data corresponding to the user's interaction with the software application as generated by the at least one remote backend computing system can be received. A new video comprising a plurality of divided segments of the user-activity video signal can be generated automatically using the backend user interaction data and a plurality of predefined rules. The new video can be provided. Related apparatus, systems, techniques, and articles are also described.

Abstract: Methods and apparatus to form biocompatible energization elements are described. In some examples, the methods and apparatus to form the biocompatible energization elements involve forming cavities comprising active cathode chemistry. The active elements of the cathode and anode are sealed with a biocompatible material. In some examples, a field of use for the methods and apparatus may include any biocompatible device or product that requires energization elements.