Patents by Inventor James David Morrison
James David Morrison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10201501Abstract: There is provided use of a mixed metal compound in the manufacture of medicament for neutralizing or buffering stomach acid, wherein the mixed metal compound contains at least one trivalent metal selected from iron (III) and aluminum and at least one divalent metal selected from of magnesium, iron, zinc, calcium, lanthanum and cerium, wherein (A) the mixed metal compound is of formula (I): MII1-aMIIIaObAn?c.zH2O (I) where MII is the at least one bivalent metal; MIII is the at least one trivalent metal; An? at least one n-valent anion; 2+a=2b+?cn and ?cn<0.9a, and z is 2 or less, and/or (B) the mixed metal compound is provided in the form of a granular material comprising (i) at least 50% by weight, based on the weight of the granular material, of the mixed metal compound (ii) from 3 to 12% by weight, based on the weight of the granular material, of non-chemically bound water, and (iii) no greater than 47% by weight based on the weight of the granular material of excipient.Type: GrantFiled: July 24, 2008Date of Patent: February 12, 2019Assignee: OPKO IRELAND GLOBAL HOLDINGS, LTD.Inventors: Maurice Sydney Newton, James David Morrison, Ruth Diane Pennel, Nigel Peter Rhodes, Alexis John Toft
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Patent number: 9907816Abstract: There is provided a granular material comprising (i) at least 50% by weight based on the weight of the granular material of solid water-insoluble mixed metal compound capable of binding phosphate of formula (I): MII1-x.MIIIx(OH)2An?y.zH2O (I) where MII is at least one of magnesium, calcium, lanthanum and cerium; MII is at least iron(III); An is at least one n-valent anion; x=?ny, 0<x?0.67, 0<y?1, and 0?z<10; (ii) from 3 to 12% by weight based on the weight of the granular material of non-chemically bound water, and (iii) no greater than 47% by weight based on the weight of the granular material of excipient.Type: GrantFiled: January 22, 2015Date of Patent: March 6, 2018Assignee: OPKO IRELAND GLOBAL HOLDINGS, LTD.Inventors: Ruth Diane Pennell, Maurice Sydney Newton, James David Morrison, Alexis John Toft, Nigel Peter Rhodes
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Publication number: 20160296557Abstract: There is provided a method of producing a mixed metal compound that includes at least Mg2+ and at least Fe3+ having an aluminum content of less than 10000 ppm, having an average crystal size of less than 20 nm (200 ?) comprising the steps of: (a) combining a Mg2+ salt and a Fe3+ salt with Na2CO3 and NaOH to produce a slurry, wherein the pH of the slurry is maintained at from 9.5 to 11, and wherein the Na2CO3 is provided at an excess of 0 to 4.0 moles than is required to complete the reaction (b) subjecting the slurry to mixing under conditions providing a power per unit volume of 0.03 to 1.6 kW/m3 (c) separating the mixed metal compound from the slurry, to obtain a crude product having a dry solid content of at least 10 wt % (d) drying the crude product.Type: ApplicationFiled: April 19, 2016Publication date: October 13, 2016Inventors: Richard Jonathan Applewhite, James David Morrison, Maurice Sydney Newton, Nigel Peter Rhodes, Christopher John Rickard
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Patent number: 9168270Abstract: There is provided a granular material comprising (i) at least 50% by weight based on the weight of the granular material of solid water-insoluble mixed metal compound capable of binding phosphate of formula (I): MII1-xMIIIx(OH)2An-y.ZH2O (I) where MII is at least one of magnesium, calcium, lanthanum and cerium; MIII is at least iron(III); An- is at least one n-valent anion; x=?ny; 0<x?0.67, 0<y?1, and 0?z<10; (ii) from 3 to 12% by weight based on the weight of the granular material of non-chemically bound water, and (iii) no greater than 47% by weight based on the weight of the granular material of excipient.Type: GrantFiled: January 30, 2007Date of Patent: October 27, 2015Assignee: OPKO IRELAND GLOBAL HOLDINGS, LTD.Inventors: Ruth Diane Pennel, Maurice Sydney Newton, James David Morrison, Alexis John Toft, Nigel Peter Rhodes
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Patent number: 9066917Abstract: There is provided a method of producing a mixed metal compound comprising at least Mg2+ and at least Fe3+ having an aluminum content of less than 10000 ppm, having an average crystal size of less than 20 nm (200 A) comprising the steps of: (a) combining a Mg2+ salt and a Fe3+ salt with Na2CO3 and NaOH to produce a slurry, wherein the pH of the slurry is maintained at from 9 5 to 1 1, and wherein the Na2CO3 is provided at an excess of 0 to 4.0 moles than is required to complete the reaction (b) subjecting the slurry to mixing under conditions providing a power per unit volume of 0 03 to 1.6 kW/m3 (c) separating the mixed metal compound from the slurry, to obtain a crude product having a dry solid content of at least 10 wt % (d) drying the crude product either by (i) heating the crude product to a temperature of no greater than 150° C. and sufficient to provide a water evaporation rate of 0.Type: GrantFiled: March 24, 2014Date of Patent: June 30, 2015Assignee: CYTOCHROMA DEVELOPMENT INC.Inventors: Richard Jonathan Applewhite, James David Morrison, Maurice Sydney Newton, Nigel Peter Rhodes, Christopher John Rickard
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Publication number: 20150132407Abstract: There is provided a granular material comprising (i) at least 50% by weight based on the weight of the granular material of solid water-insoluble mixed metal compound capable of binding phosphate of formula (I): MII1-x.MIIIx(OH)2An?y.zH2O (I) where MII is at least one of magnesium, calcium, lanthanum and cerium; MII is at least iron(III); A is at least one n-valent anion; x=?ny, 0<x?0.67, 0<y?1, and 0?z<10; (ii) from 3 to 12% by weight based on the weight of the granular material of non-chemically bound water, and (iii) no greater than 47% by weight based on the weight of the granular material of excipient.Type: ApplicationFiled: January 22, 2015Publication date: May 14, 2015Inventors: Ruth Diane Pennel, Maurice Sydney Newton, James David Morrison, Alexis John Toft, Nigel Peter Rhodes
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Publication number: 20140205667Abstract: There is provided a method of producing a mixed metal compound comprising at least Mg2+ and at least Fe3 + having an aluminium content of less than 10000 ppm, having an average crystal size of less than 20 nm (200 A) comprising the steps of: (a) combining a Mg2+ salt and a Fe3 + salt with Na2CO3 and NaOH to produce a slurry, wherein the pH of the slurry is maintained at from 9 5 to 1 1, and wherein the Na2CO3 is provided at an excess of 0 to 4.0 moles than is required to complete the reaction (b) subjecting the slurry to mixing under conditions providing a power per unit volume of 0 03 to 1.6 kW/m3 (c) separating the mixed metal compound from the slurry, to obtain a crude product having a dry solid content of at least 10 wt % (d) drying the crude product either by (i) heating the crude product to a temperature of no greater than 150° C. and sufficient to provide a water evaporation rate of 0.Type: ApplicationFiled: March 24, 2014Publication date: July 24, 2014Applicant: CYTOCHROMA DEVELOPMENT INC.Inventors: Richard Jonathan Applewhite, James David Morrison, Maurice Sydney Newton, Nigel Peter Rhodes, Christopher John Rickard
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Publication number: 20100203152Abstract: There is provided use of a mixed metal compound in the manufacture of medicament for neutralising or buffering stomach acid, wherein the mixed metal compound contains at least one trivalent metal selected from iron (III) and aluminium and at least one divalent metal selected from of magnesium, iron, zinc, calcium, lanthanum and cerium, wherein (A) the mixed metal compound is of formula (I): MII1-aMIIIaObAn-c.zH2O (I) where MII is the at least one bivalent metal; MIII is the at least one trivalent metal; An- at least one n-valent anion; 2+a=2b+?cn and ?cn<0.9a, and z is 2 or less, and/or (B) the mixed metal compound is provided in the form of a granular material comprising (i) at least 50% by weight, based on the weight of the granular material, of the mixed metal compound (ii) from 3 to 12% by weight, based on the weight of the granular material, of non-chemically bound water, and (iii) no greater than 47% by weight based on the weight of the granular material of excipient.Type: ApplicationFiled: July 24, 2008Publication date: August 12, 2010Applicant: Ineos Healthcare KimitedInventors: Maurice Sydney Newton, James David Morrison, Ruth Diane Pennell, Nigel Peter Phodes, Alexis John Toft
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Publication number: 20090317459Abstract: There is provided a granular material comprising (i) at least 50% by weight based on the weight of the granular material of solid water-insoluble mixed metal compound capable of binding phosphate of formula (I): MII1?xMIIIx(OH)2?n?y.ZH2O (I) where MII is at least one of magnesium, calcium, lanthanum and cerium; MIII is at least iron(III); ?n? is at least one n-valent anion; x=?ny; 0<x?0.67, 0<y?1, and 0?z<10; (ii) from 3 to 12% by weight based on the weight of the granular material of non-chemically bound water, and (iii) no greater than 47% by weight based on the weight of the granular material of excipient.Type: ApplicationFiled: January 30, 2007Publication date: December 24, 2009Inventors: Ruth Diane Pennel, Manrice Sydney Newton, James David Morrison, Alexis John Toft, Nigel Peter Rhodes
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Patent number: 7485207Abstract: A closed-loop biomass extraction apparatus using HFC solvents including an extraction vessel, an evaporator for the solvent, a compressor and a condenser connected in series in a closed loop extraction circuit; a solvent recovery loop constituted by a bypass line; a plurality of flow control valves that are selectively operable for connecting the solvent recovery loop in parallel with the closed loop extraction circuit; and at least one container containing an adsorbent for organic contaminants and a desiccant, the container being connected in the solvent recovery loop to which solvent in the extraction circuit may be supplied through selective operation of the flow control valves whereby solvent used in the extraction circuit may be supplied through the adsorbent and the desiccant.Type: GrantFiled: May 29, 2003Date of Patent: February 3, 2009Assignee: Ineos Fluor Holdings LimitedInventors: Stuart Corr, Paul A. Dowdle, Robert E. Low, James David Morrison, Frederick Thomas Murphy
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Patent number: 7001511Abstract: In the field of biomass extraction, there is a need for effective removal of solvent from spent biomass material. An apparatus for removing solvent residues includes a vessel (11) for containing biomass; a steam source (19) for supplying steam to contact the biomass; and a separator (24) for separating solvent from steam that has contacted the biomass. The disclosure also includes a method of use of the apparatus.Type: GrantFiled: July 18, 2003Date of Patent: February 21, 2006Assignee: Ineous Fluor Holdings LimitedInventors: Stuart Corr, Paul A. Dowdle, Robert E. Low, James David Morrison, Frederick Thomas Murphy
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Patent number: 6918950Abstract: Apparatus and methods for reducing residual solvent levels in extracted biomass that is contaminated with HFC solvent that includes sparging the biomass extract with a solvent stripping gas such as air or nitrogen are disclosed. Apparatus for carrying out the method include a vessel (12;25) containing extract (26) and a source of the gas. The source may be in the form of a moveable, hollow wand (27) having a sparging gas outlet; or a fixed gas inlet (30) for bubbling the gas through the extract (26).Type: GrantFiled: January 10, 2003Date of Patent: July 19, 2005Assignee: Ineos Fluor Holdings LimitedInventors: Stuart Corr, Paul A. Dowdle, Robert E. Low, Frederick Thomas Murphy, James David Morrison
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Patent number: 6710216Abstract: In a closed-loop biomass extraction apparatus (10), strategies for purifying HFC solvents used therein include: (i) contacting an adsorbent and a desiccant, e.g. in a container (26) with contaminated HFC solvent branched from the main flow loop; and, optionally, (ii) washing contaminated HFC solvent with water, e.g. in a vessel (34) to separate a co-solvent or entrainer, such as ethanol, thereform.Type: GrantFiled: September 5, 2000Date of Patent: March 23, 2004Assignee: Imperial Chemical Industries PLCInventors: Stuart Corr, Paul A. Dowdle, Robert E. Low, James David Morrison, Frederick Thomas Murphy
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Patent number: 6685839Abstract: In the field of biomass extraction, there is a need for effective removal of solvent from spent biomass material. An apparatus for removing solvent residues includes a vessel (11) for containing biomass; a steam source (19) for supplying steam to contact the biomass; and a separator (24) for separating solvent from steam that has contacted the biomass. The disclosure includes a method of use of the apparatus.Type: GrantFiled: September 5, 2000Date of Patent: February 3, 2004Assignee: Ineos Fluor Holdings LimitedInventors: Stuart Corr, Paul A. Dowdle, Robert E. Low, James David Morrison, Frederick Thomas Murphy
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Publication number: 20040016704Abstract: In the field of biomass extraction, there is a need for effective removal of solvent from spent biomass material.Type: ApplicationFiled: July 18, 2003Publication date: January 29, 2004Inventors: Stuart Corr, Paul A. Dowdle, Robert E. Low, James David Morrison, Frederick Thomas Murphy
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Patent number: 6676838Abstract: An apparatus (10′) for extracting biomass includes an extractor (11), evaporator (12), compressor (13) and condenser (14) connected in series by pipework (17) to define a closed loop extraction circuit. A transfer line (18) selectively supplies hot solvent vapor from the outlet side of the compressor (13) to the interior of the extractor (11), where the solvent vapor heats the biomass. This causes stripping of solvent from the biomass. The transfer line (18) includes control elements (19,20) for controlling the flow of solvent vapor.Type: GrantFiled: February 27, 2002Date of Patent: January 13, 2004Assignee: Ineos Fluor Holdings LimitedInventors: Stuart Corr, Paul A. Dowdle, Robert E. Low, Frederick Thomas Murphy, James David Morrison
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Patent number: 6667015Abstract: An apparatus for extracting biomass includes a closed loop circuit having an extraction vessel (11), an evaporator (12), a compressor (13), a condenser (14) and (optionally) a storage reservoir (15) operatively connected in series. A pumped recirculation loop (20) recirculates a portion of the output of the extraction vessel (11) for further contact with biomass. One or more modifiable resistances to flow (12;23) control the flow of solvent around the recirculation loop (20) and the main closed loop.Type: GrantFiled: September 5, 2000Date of Patent: December 23, 2003Assignee: Ineos Fluor Holdings LimitedInventors: Robert E. Low, Stuart Corr, Frederick Thomas Murphy, James David Morrison
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Publication number: 20030204119Abstract: In a closed-loop biomass extraction apparatus (10), strategies for purifying HFC solvents used therein include:Type: ApplicationFiled: May 29, 2003Publication date: October 30, 2003Inventors: Stuart Corr, Paul A. Dowdle, Robert E. Low, James David Morrison, Frederick Thomas Murphy
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Publication number: 20030101870Abstract: A method of reducing residual solvent levels in extracted biomass that is contaminated with HFC solvent includes sparging the biomass extract with a solvent stripping gas such as air or Nitrogen.Type: ApplicationFiled: January 10, 2003Publication date: June 5, 2003Inventors: Stuart Corr, Paul A. Dowdle, Robert E. Low, Frederick Thomas Murphy, James David Morrison
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Patent number: 6521022Abstract: Apparatus and methods for reducing residual solvent levels in extracted biomass that is contaminated with HFC solvent that includes sparging the biomass extract with a solvent stripping gas such as air or nitrogen are disclosed. Apparatus for carrying out the method include a vessel (12;25) containing extract (26) and a source of the gas. The source may be in the form of a moveable, hollow wand (27) having a sparging gas outlet; or a fixed gas inlet (30) for bubbling the gas through the extract (26).Type: GrantFiled: September 5, 2000Date of Patent: February 18, 2003Assignee: Ineos Fluor Holdings LimitedInventors: Stuart Corr, Paul A. Dowdle, Robert E. Low, Frederick Thomas Murphy, James David Morrison