Abstract: Infusion pump control unit keypad assemblies are provided, and include a cover assembly having an outer surface and an inner surface and a perimeter gasket disposed within a raised perimeter on the outer surface of the cover assembly. A lens and a circuit assembly are coupled to the outer surface of the cover assembly. A switch assembly is coupled to the circuit assembly, a shield assembly is coupled to the switch assembly, a light assembly is coupled to the shield assembly and an overlay assembly is coupled to the light assembly. Methods of making infusion pump control unit keypad assemblies are also provided.