Patents by Inventor James Dodge

James Dodge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200306387
    Abstract: The disclosure pertains to methods and compositions for treating disorders affecting the central nervous system (CNS). These disorders include neurometabolic disorders such as lysosomal storage diseases that affect the central nervous system, e.g., Niemann-Pick A disease. They also include disorders such as Alzheimer's disease. The disclosed methods involve contacting an axonal ending of a neuron with a composition containing high titer AAV carrying a therapeutic transgene so that the AAV vector is axonally transported in a retrograde fashion and transgene product is expressed distally to the administration site.
    Type: Application
    Filed: March 3, 2020
    Publication date: October 1, 2020
    Inventors: Marco A. PASSINI, James DODGE
  • Patent number: 10744210
    Abstract: This disclosure provides methods and compositions for treating disorders or injuries that affect motor function and control in a subject. In one aspect, the invention provides a method to deliver a transgene to a subject's spinal cord by administering a recombinant neurotropic viral vector containing the transgene. The viral vector delivers the transgene to a region of the deep cerebellar nuclei region of the brain. Also provided are compositions and methods to deliver a transgene to a subject's spinal cord by administering a recombinant neurotropic viral vector containing the transgene to the motor cortex region of the subject's brain.
    Type: Grant
    Filed: November 2, 2007
    Date of Patent: August 18, 2020
    Assignee: GENZYME CORPORATION
    Inventors: James Dodge, Lamya Shihabuddin, Marco Passini, Seng H. Cheng, Catherine O'Riordan
  • Patent number: 10724285
    Abstract: A dampening translator for a sliding building closure comprising a housing having a longitudinal axis and a traveler track with a longitudinally extending portion having a first end. A traveler is carried by the housing and includes a body carrying track followers carried in the traveler track of the housing, and carrying longitudinally spaced walls extending away from the body and establishing a catch space therebetween. A retractor is carried by the housing and has a housing portion coupled to the housing and a traveler portion coupled to the traveler to bias the traveler in a direction toward the first end of the traveler track. A dampener is carried by the housing to decelerate the traveler.
    Type: Grant
    Filed: June 14, 2016
    Date of Patent: July 28, 2020
    Assignee: MILGARD MANUFACTURING INCORPORATED
    Inventors: Travis James Dodge, Michael Barton, Eric Baczuk
  • Patent number: 10632213
    Abstract: The disclosure pertains to methods and compositions for treating disorders affecting the central nervous system (CNS). These disorders include neurometabolic disorders such as lysosomal storage diseases that affect the central nervous system, e.g., Niemann-Pick A disease. They also include disorders such as Alzheimer's disease. The disclosed methods involve contacting an axonal ending of a neuron with a composition containing high titer AAV carrying a therapeutic transgene so that the AAV vector is axonally transported in a retrograde fashion and transgene product is expressed distally to the administration site.
    Type: Grant
    Filed: November 2, 2007
    Date of Patent: April 28, 2020
    Assignee: GENZYME CORPORATION
    Inventors: Marco A. Passini, James Dodge
  • Publication number: 20200101138
    Abstract: This disclosure provides methods and compositions for treating disorders or injuries that affect motor function and control in a subject. In one aspect, the invention a transgene product is delivered to a subject's spinal cord by administering a recombinant neurotrophic viral vector containing the transgene to the brain. The viral vector delivers the transgene to a region of the brain which is susceptible to infection by the virus and which expresses the encoded recombinant viral gene product. Also provided are compositions for delivery of a transgene product to a subject's spinal cord by administering a recombinant neurotrophic viral vector containing the transgene to the subject's brain.
    Type: Application
    Filed: August 20, 2019
    Publication date: April 2, 2020
    Inventors: James DODGE, Lamya SHIHABUDDIN, Catherine O'RIORDAN
  • Patent number: 10363360
    Abstract: Pump cassettes, infusion systems, and methods are described. An example pump cassette may include a rigid body comprising a frame portion, a base portion, a compliant membrane disposed substantially therebetween, and two opposing longitudinal edge sections. The rigid body may include a controllable fluid pathway defined in part by the compliant membrane and extending from an inlet port to an outlet port. The pump cassette may include a slider coupled to the two opposing longitudinal edge sections and longitudinally articulable with respect to the rigid body.
    Type: Grant
    Filed: December 1, 2014
    Date of Patent: July 30, 2019
    Assignee: CareFusion 2200, Inc.
    Inventors: Daniel Toro, Robert Vasko, Santiago Dodge, Daniel Abal, Corey Michael Magers, Edward Browka, James Fentress, Charles E. McCall, Jr.
  • Publication number: 20190205345
    Abstract: A social networking aggregator computer program that filters user updates from several sources and merges them with geo-tagging data to provide real-time “weather maps” of symptoms and ailments, which can then be used to forecast where and when illnesses spread. Data sources include, but are not limited to popular social media “user broadcasting” platforms, social network sites and smartphone applications.
    Type: Application
    Filed: March 14, 2019
    Publication date: July 4, 2019
    Inventors: Graham Dodge, James Sajor, Michael Belt
  • Patent number: 10335541
    Abstract: Pump cassettes, infusion systems, and methods are described. An example pump cassette may include a rigid body including two opposing edge sections, an inlet port, an outlet port, and a controllable fluid pathway extending from the inlet port to the outlet port. The pump may include a slider coupled to the two opposing edge sections and articulable with respect to the rigid body; and a flow stop valve operably coupled to the controllable fluid pathway.
    Type: Grant
    Filed: December 2, 2014
    Date of Patent: July 2, 2019
    Assignee: CareFusion 2200, Inc.
    Inventors: Corey Michael Magers, Daniel Toro, Daniel Abal, Santiago Dodge, Robert Steven Vasko, Edward Browka, James Fentress, Charles E. McCall, Jr.
  • Publication number: 20190083582
    Abstract: Lysosomal storage diseases can be successfully treated using intraventricular delivery of the enzyme which is etiologically deficient in the disease. The administration can be performed slowly to achieve maximum effect. Surprisingly, effects are seen on both sides of the blood-brain barrier, making this an ideal delivery means for lysosomal storage diseases which affect both brain and visceral organs.
    Type: Application
    Filed: August 23, 2018
    Publication date: March 21, 2019
    Inventors: James DODGE, Marco A. PASSINI, Lamya SHIHABUDDIN, Seng H. CHENG
  • Patent number: 10138658
    Abstract: A fenestration assembly includes a frame assembly, a movable sash assembly and a lock assembly. The lock assembly includes a first lock and a second side lock. The first lock operatively locks and unlocks the moveable sash to the frame assembly in a first direction only when the movable sash is in a fully closed position. The first side lock operatively locks and unlocks the movable sash in a second direction perpendicular to the first direction both when the movable sash is in the fully closed position and a partially open position.
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: November 27, 2018
    Assignee: MILGARD MANUFACTURING INCORPORATED
    Inventors: Michael A. Barton, Travis James Dodge
  • Patent number: 10080783
    Abstract: Lysosomal storage diseases can be successfully treated using intraventricular delivery of the enzyme which is etiologically deficient in the disease. The administration can be performed slowly to achieve maximum effect. Surprisingly, effects are seen on both sides of the blood-brain barrier, making this an ideal delivery means for lysosomal storage diseases which affect both brain and visceral organs.
    Type: Grant
    Filed: December 3, 2014
    Date of Patent: September 25, 2018
    Assignee: Genzyme Corporation
    Inventors: James Dodge, Marco A. Passini, Lamya Shihabuddin, Seng H. Cheng
  • Publication number: 20170350174
    Abstract: A fenestration assembly includes a frame assembly, a movable sash assembly and a lock assembly. The lock assembly includes a first lock and a second side lock. The first lock operatively locks and unlocks the moveable sash to the frame assembly in a first direction only when the movable sash is in a fully closed position. The first side lock operatively locks and unlocks the movable sash in a second direction perpendicular to the first direction both when the movable sash is in the fully closed position and a partially open position.
    Type: Application
    Filed: June 3, 2016
    Publication date: December 7, 2017
    Applicant: Milgard Manufacturing Incorporated
    Inventors: Michael A. Barton, Travis James Dodge
  • Patent number: 9772010
    Abstract: A building closure operator includes an operator arm pivotable about an arm axis from an arm closed position to an arm open position, an arm lock actuatable to lock the arm in different locked positions and releasable to release the arm, and an articulatable lever pivotable about a lever axis parallel to the arm axis, from a lever home position corresponding to the arm closed position, to a lever actuated position corresponding to the arm open position. The lever includes a lever coupling maintainable in the lever actuated position, and a lever handle pivotable with respect to the lever coupling back to the home position to actuate the arm lock to lock the arm in one of the different locked positions.
    Type: Grant
    Filed: June 14, 2016
    Date of Patent: September 26, 2017
    Assignee: Milgard Manufacturing Incorporation
    Inventors: Travis James Dodge, Michael Barton, Eric Baczuk
  • Publication number: 20160369549
    Abstract: A building closure operator includes an operator arm pivotable about an arm axis from an arm closed position to an arm open position, an arm lock actuatable to lock the arm in different locked positions and releasable to release the arm, and an articulatable lever pivotable about a lever axis parallel to the arm axis, from a lever home position corresponding to the arm closed position, to a lever actuated position corresponding to the arm open position. The lever includes a lever coupling maintainable in the lever actuated position, and a lever handle pivotable with respect to the lever coupling back to the home position to actuate the arm lock to lock the arm in one of the different locked positions.
    Type: Application
    Filed: June 14, 2016
    Publication date: December 22, 2016
    Inventors: Travis James Dodge, Michael Barton, Eric Baczuk
  • Publication number: 20160369548
    Abstract: A dampening translator for a sliding building closure. A housing extends along a longitudinal axis and includes a traveler track with a longitudinally extending portion having a first end. A traveler is carried by the housing and includes a body carrying track followers carried in the traveler track of the housing, and longitudinally spaced walls extending away from the body and establishing a catch space therebetween. A retractor is carried by the housing and has a housing portion coupled to the housing and a traveler portion coupled to the traveler to bias the traveler in a direction toward the first end of the traveler track. A dampener is carried by the housing to decelerate the translator.
    Type: Application
    Filed: June 14, 2016
    Publication date: December 22, 2016
    Inventors: Travis James Dodge, Michael Barton, Eric Baczuk
  • Publication number: 20160353921
    Abstract: A machine and system in the art of precision cooking, which can be a stand-alone appliance, or integrated into a thermally insulated chamber; the machine having means to collect geometric, physical, and thermal values; having access to an electronic database of material composition values, a program which through onboard micro-computing or connection to external computing resources, generates a three-dimensional thermo physical model of the irregular shaped food object to be cooked, relating obtained values as to retrieve essential heat conduction variables to render an accurate cook time. The machine and system, once integrated inside a thermally insulated chamber, or in communication with a thermally insulated chamber through an IoT communication platform can, once cook time is calculated, receive feedback from user through a display—this feedback assists in ensuring accurate precision of cooking time by slightly changing the individual users machine to account for irregular variables in the system.
    Type: Application
    Filed: June 3, 2015
    Publication date: December 8, 2016
    Inventor: Travis James Dodge
  • Publication number: 20160287549
    Abstract: The invention relates to dihydroorate dehydrogenase (DHODH) inhibitors useful for the treatment of neurodegenerative diseases, such as amyotrophic lateral sclerosis.
    Type: Application
    Filed: November 21, 2014
    Publication date: October 6, 2016
    Inventor: James DODGE
  • Patent number: 9441414
    Abstract: A sliding fenestration sash assembly includes a sliding sash and a frame having a first longitudinal member including at least one aperture. A pin is operatively connected to a handle and movable between an extended position and a retracted position. The pin is biased toward the first longitudinal member by a biasing member. The pin being biased into the aperture by the biasing member when the pin is aligned with the aperture.
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: September 13, 2016
    Assignee: MILGARD MANUFACTURING INCORPORATED
    Inventors: Eric A. Baczuk, Travis James Dodge, Michael A. Barton
  • Patent number: 9404295
    Abstract: A sliding fenestration sash assembly includes a sliding sash and a frame having a first longitudinal member including at least one aperture. A pin is operatively connected to a handle and movable between a first position and a second position. The pin being biased into the aperture by the biasing member when the pin is aligned with the aperture.
    Type: Grant
    Filed: May 14, 2015
    Date of Patent: August 2, 2016
    Assignee: MILGARD MANUFACTURING INCORPORATED
    Inventors: Eric A. Baczuk, Travis James Dodge
  • Publication number: 20160067312
    Abstract: This disclosure provides methods and compositions for treating disorders or injuries that affect motor function and control in a subject. In one aspect, the invention a transgene product is delivered to a subject's spinal cord by administering a recombinant neurotrophic viral vector containing the transgene to the brain. The viral vector delivers the transgene to a region of the brain which is susceptible to infection by the virus and which expresses the encoded recombinant viral gene product. Also provided are compositions for delivery of a transgene product to a subject's spinal cord by administering a recombinant neurotrophic viral vector containing the transgene to the subject's brain.
    Type: Application
    Filed: April 21, 2015
    Publication date: March 10, 2016
    Inventors: James DODGE, Lamya SHIHABUDDIN, Catherine O'RIORDAN