Abstract: Delivery systems adapted for implementation during a brachytherapy procedure are provided. The delivery system includes a plurality of brachytherapy seeds and a plurality of spacers. Each spacer is formed of a matrix material carrying a plurality of microparticles and/or nanoparticles. The microparticles and/or nanoparticles carry an agent and are biodegradable and/or biocompatible. The brachytherapy seeds and the spacers are configured to be delivered to a target site. Associated methods are also provided.

Abstract: A mass exchange device and system that employs a semi-permeable diffusion barrier in the nature of a tubular membrane. A sample gas stream conduit is concentric with the tubular membrane, and the transport gas stream flows within the tubular membrane in a direction opposite to the flow of transport gas stream. Certain molecular species in the sample gas migrate across the tubular membrane and mix with the transport gas for passage to an analyzer. The conduit and tubular membranes are incorporated within a heat exchange cartridge and a heater and temperature controller maintain a desired temperature control of the system. Dual stream dilutions may be accomplished by sampling an exhaust gas prior to cleansing by a gas scrubber and also sampling the gas after cleansing. Both the upstream and downstream sample gases are diluted in a common heat exchange cartridge and passed to an analyzer.