Patents by Inventor James Duane Brooks

James Duane Brooks has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methylation Biomarkers for Diagnosis of Prostate Cancer
    Publication number: 20140094380
    Abstract: Biomarkers for diagnosis and prognosis of prostate cancer are provided. The biomarkers are promoter sequences have altered methylation patterns relative to normal prostate tissue. Altered expression of DNA methyltransferases (DNMT) and proteins that interact with DNMT result in increased methylation at a subset of prostate tumor hypermethylation sites.
    Type: Application
    Filed: April 2, 2012
    Publication date: April 3, 2014
    Applicant: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Gavin J. Sherlock, James Duane Brooks, Richard M. Myers, Yuya Kobayashi, Devin M. Absher
  • Markers of DNA copy number alteration for improved prognostication in prostate cancer
    Patent number: 7638278
    Abstract: The invention describes DNA copy number alterations (CNAs), identifiable by technologies such as array-based comparative genomic hybridization (array CGH) or fluorescence in situ hybridization (FISH), that define distinct genetic subtypes of prostate cancer, and are useful for improved prognostication and treatment stratification for patients with prostate cancer.
    Type: Grant
    Filed: May 12, 2006
    Date of Patent: December 29, 2009
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Jonathan Robert Pollack, Jacques Lapointe, James Duane Brooks