Abstract: A pharmaceutical composition is provided comprising a vitamin E derivative, an anionic phopholipid-binding protein, an anionic phospholipid and a sterol. Also provided is a method for preparing a composition for delivering a cargo to a subject comprising a) forming liposomes from a vitamin E derivative, an anionic phospholipid-binding protein such as annexin, an anionic phospholipid such as phosphatidylserine and a sterol; and b) encapsulating the cargo in the liposomal composition.

Abstract: Gum manufacturing machinery and method of manufacturing gum is illustrated in which a gum loafing machine generates loaves of finished gum that are then subsequently run through a gum conditioner to more uniformly set the temperature and viscosity of the gum material prior to further processing. Upon achieving the appropriate conditioning level, a further forming extruder may be used to generate a continuous gum ribbon for subsequent rolling and scoring operations. The gum conditioner may include vertically stacked conveyors that have different operational modes including a first mode that provides a serpentine path for a long residence time and a second mode that provides a cascading path that avoids or bypasses much of the length of some of the conveyors to provide a shorter residence time. The gum manufacturing machinery may be used in an adjustable manner so as to accommodate difference gum recipes for different batches of gum product.

Abstract: Gum manufacturing machinery and method of manufacturing gum is illustrated in which a gum loafing machine generates loaves of finished gum that are then subsequently run through a gum conditioner to more uniformly set the temperature and viscosity of the gum material prior to further processing. Upon achieving the appropriate conditioning level, a further forming extruder may be used to generate a continuous gum ribbon for subsequent rolling and scoring operations. The gum conditioner may include vertically stacked conveyors that have different operational modes including a first mode that provides a serpentine path for a long residence time and a second mode that provides a cascading path that avoids or bypasses much of the length of some of the conveyors to provide a shorter residence time. The gum manufacturing machinery may be used in an adjustable manner so as to accommodate difference gum recipes for different batches of gum product.

Abstract: Gum manufacturing machinery and method of manufacturing gum is illustrated in which a gum loafing machine generates loaves of finished gum that are then subsequently run through a gum conditioner to more uniformly set the temperature and viscosity of the gum material prior to further processing. Upon achieving the appropriate conditioning level, a further forming extruder may be used to generate a continuous gum ribbon for subsequent rolling and scoring operations. The gum conditioner may include vertically stacked conveyors that have different operational modes including a first mode that provides a serpentine path for a long residence time and a second mode that provides a cascading path that avoids or bypasses much of the length of some of the conveyors to provide a shorter residence time. The gum manufacturing machinery may be used in an adjustable manner so as to accommodate difference gum recipes for different batches of gum product.

Abstract: A pharmaceutical composition is provided comprising a vitamin E derivative, an anionic phopholipid-binding protein, an anionic phospholipid and a sterol. Also provided is a method for preparing a composition for delivering a cargo to a subject comprising a) forming liposomes from a vitamin E derivative, an anionic phospholipid-binding protein such as annexin, an anionic phospholipid such as phosphatidylserine and a sterol; and b) encapsulating the cargo in the liposomal composition.

Abstract: A hybrid electro-hydraulic drive system is provided for a vehicle and comprises a hydraulic transmission including a first hydraulic machine and at least one second hydraulic machine drivingly connected to drive wheels of the motor vehicle for driving thereof, an electric motor/generator operatively connected to the first hydraulic machine, and at least one energy storage device operable to store and release a hydraulic fluid energy or an electrical energy. The second hydraulic machine is a reversible hydraulic pump/motor unit capable to function both as a hydraulic pump and a hydraulic motor. The energy storage device is operatively connected to either the hydraulic transmission or the electric motor/generator. In a retarding mode the hydraulic transmission and/or the electric motor/generator retard the vehicle, while in a driving mode they supply a supplementary power to the drive wheels to assist propulsion of the vehicle.

Abstract: Methods and apparatuses are provided for conveying gum components and for making chewing gum compositions, by conveying a substantially horizontally stratified flow of two or more gum components along a conveying path. Once the horizontally stratified flow of gum components is established, the flow of gum components can be supplied to a gum mixing machine in a substantially constant cross-sectional ratio of the gum components, even where it is necessary to adjust the rate of flow of gum components along the conveying path, or to periodically start and stop the flow of components during the gum making process.

Abstract: The present invention provides a method for continuously producing pieces of liquid-filled gum material, including applying an anti-sticking agent to the rope of liquid-filled gum material before it is individually cut into pieces. The invention further provides for a liquid-filled chewing gum including a liquid-fill composition, and a gum region surrounding the liquid-fill composition, where the gum region includes an anti-sticking agent that reduces the tendency of the gum region to stick to the molds and operating machinery during gum manufacturing.

Abstract: Gum manufacturing machinery and method of manufacturing gum is illustrated in which a gum loafing machine generates loaves of finished gum that are then subsequently run through a gum conditioner to more uniformly set the temperature and viscosity of the gum material prior to further processing. Upon achieving the appropriate conditioning level, a further forming extruder may be used to generate a continuous gum ribbon for subsequent rolling and scoring operations. The gum conditioner may include vertically stacked conveyors that have different operational modes including a first mode that provides a serpentine path for a long residence time and a second mode that provides a cascading path that avoids or bypasses much of the length of some of the conveyors to provide a shorter residence time. The gum manufacturing machinery may be used in an adjustable manner so as to accommodate difference gum recipes for different batches of gum product.

Abstract: The present invention provides a method for continuously producing pieces of liquid-filled gum material, including applying an anti-sticking agent to the rope of liquid-filled gum material before it is individually cut into pieces. The invention further provides for a liquid-filled chewing gum including a liquid-fill composition, and a gum region surrounding the liquid-fill composition, where the gum region includes an anti-sticking agent that reduces the tendency of the gum region to stick to the molds and operating machinery during gum manufacturing.

Abstract: A method of manufacturing a splined member avoids the generation of waste material and minimizes the amount of dimensional inaccuracies. A hollow cylindrical workpiece is initially provided from a material having a relatively high elongation characteristic. The material used to form the workpiece may be AA-5154 grade aluminum alloy having an elongation characteristic that is in the range of from about 20% to about 30%, preferably in the range of from about 22% to about 28%, and most preferably about 25%. A mandrel having a plurality of external splines is inserted within workpiece, and the workpiece is deformed into engagement with the mandrel to form a splined member using a swaging process, such a rotary swaging or feed swaging. The splined member is thus formed having a plurality of internal splines and a cylindrical outer surface. The use of the swaging process avoids the generation of waste material.

Abstract: A system and method for mixing and forming gum structures is provided. The system may include combinations of continuous and batch mixers arranged generally in series for mixing gum base ingredients with subsequent gum ingredients. In one embodiment, the system and method first forms a gum structure that is not a gum base and then adds a subsequent gum ingredient such that the gum structure is less than a gum base in combination with a subsequent gum ingredient. In other embodiments, the system and method includes forming a gum base in addition to some subsequent gum ingredients that are not quite finished gum. Further, in other embodiments, the system and method may perform some of the mixing of the ingredients at a first location while mixing of further ingredients is performed at a remote location.

Abstract: A system and method for mixing and forming gum structures is provided. The system may include combinations of continuous and batch mixers arranged generally in parallel and/or series for mixing gum base ingredients with subsequent gum ingredients. In one embodiment, the system and method first forms a gum structure that is not a gum base and then adds a subsequent gum ingredient such that the gum structure is less than a gum base in combination with a subsequent gum ingredient. In other embodiments, the system and method includes forming a gum base in addition to some subsequent gum ingredients that are not quite finished gum. Further, in other embodiments, the system and method may perform some of the mixing of the ingredients at a first location while mixing of further ingredients is performed at a remote location.

Abstract: A center bearing assembly has an adjustable pneumatic support member for absorbing vibrations. The bearing assembly includes a bearing and a support member assembly that supports the bearing. The support member assembly includes a bladder having an interior chamber that is filled with a fluid. A bracket is provided that supports the support member assembly for pivoting movement relative thereto. A system is provided for controlling the magnitude of the fluid pressure within the interior chamber of the bladder. The system includes a plurality of sensors that generate signals that are representative of a plurality of operating conditions. A controller is responsive to the sensor signals and generates a signal to a pressure regulating device that controls the magnitude of the fluid pressure within the interior chamber of the bladder.

Abstract: A hybrid electro-hydraulic drive system is provided for a vehicle and comprises a hydraulic transmission including a first hydraulic machine and at least one second hydraulic machine drivingly connected to drive wheels of the motor vehicle for driving thereof, an electric motor/generator operatively connected to the first hydraulic machine, and at least one energy storage device operable to store and release a hydraulic fluid energy or an electrical energy. The second hydraulic machine is a reversible hydraulic pump/motor unit capable to function both as a hydraulic pump and a hydraulic motor. The energy storage device is operatively connected to either the hydraulic transmission or the electric motor/generator. In a retarding mode the hydraulic transmission and/or the electric motor/generator retard the vehicle, while in a driving mode they supply a supplementary power to the drive wheels to assist propulsion of the vehicle.

Abstract: Method and system for continuously producing pieces of liquid-filled gum material. An extruded rope of liquid-filed gum is sized and separated into individual pieces of gum. A rotating drum mechanism having a die ring and cutter ring with mating die members separate the rope of gum material into individual pieces. Pairs of cam-operated plunger members compress and form the pieces of gum material in the die cavities. Angled grooves in the die members prevent portions of the gum pieces from being chipped-off during formation. Guide pin members are positioned between rider members on the plunger members. A feed chute with air assist transfers the gum rope from a sizing table to the rotating drum mechanism. A stripper member insures that the formed pieces of gum material are removed from the drum mechanism. Portions of the drum mechanism can be selective heated and cooled, or not cooled at all. The invention provides a more efficient system for continuous, high production operation.

Abstract: A driveshaft assembly includes a yoke including a body portion, a pair of opposed yoke arms that extends generally in a first axial direction from the body portion, and a neck portion that extends generally in a second axial direction from the body portion. A driveshaft tube is secured to the neck portion of the yoke, such as by magnetic pulse welding. A ring is secured to the body portion of the yoke, such as by press fitting, and a balance weight is secured to the ring, such as by welding.

Abstract: A method of manufacturing a delivery system of at least one active component encapsulated in an encapsulating material, which is useful, for example, for providing delayed and/or controlled release of the active is described.

Abstract: The present invention provides a method for continuously producing pieces of liquid-filled gum material, including applying an anti-sticking agent to the rope of liquid-filled gum material before it is individually cut into pieces. The invention further provides for a liquid-filled chewing gum including a liquid-fill composition, and a gum region surrounding the liquid-fill composition, where the gum region includes an anti-sticking agent that reduces the tendency of the gum region to stick to the molds and operating machinery during gum manufacturing.

Abstract: The disclosed system and method may monitor and track people, objects or assets. A monitoring unit can monitor and track a number of monitored units. When a monitored unit exceed a certain distance from the monitoring unit an alarm is triggered to notify both the monitoring unit and the monitored unit. A parent or teacher may utilize a monitoring unit for a group of kids whom all have a monitored unit. The parent or teacher can easily monitor and track the kids with a monitoring system. Alternatively, the monitoring system can be used in a nursing home situation, for tracking pets, or other assets.