Patents by Inventor James E. Aldred

James E. Aldred has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process of enantiomeric resolution of D,L-(+_)-threo-methylphenidate
    Publication number: 20080167470
    Abstract: A process for preparing the d-threo isomer of methylphenidate hydrochloride which includes (i) resolving a racemic mixture of racemic threo-methylphenidate hydrochloride with a less than stoichiometric amount of tertiary amine base to obtain a methylphenidate-chiral acid salt, (ii) basifying the methylphenidate-chiral acid salt to obtain methylphenidate free base, and (iii) converting the methylphenidate free base into d-threo-methylphenidate hydrochloride.
    Type: Application
    Filed: January 5, 2007
    Publication date: July 10, 2008
    Inventors: Alexei Kalinin, Guofang Qiu, Thomas J. Marren, James E. Aldred, Yu Ji