Patents by Inventor James E. Booth

James E. Booth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Binding molecules for human factor VIII and factor VIII-like proteins
    Patent number: 9156883
    Abstract: It is an object of the present invention to provide novel binding molecules for factor VIII and factor VIII-like proteins. Preferred binding molecules of the present invention exhibit not only distinct characteristics for binding of the target factor VIII polypeptides but also specific and desirable characteristics for release (elution) of the target polypeptides. Especially preferred binding molecules according to the invention are short polypeptide sequences, characterized by a stable loop structure.
    Type: Grant
    Filed: August 14, 2013
    Date of Patent: October 13, 2015
    Assignee: Dyax Corp.
    Inventors: Jinan Yu, M. Daniel Potter, Brian D. Kelley, Jeffrey S. Deetz, James E. Booth
  • BINDING MOLECULES FOR HUMAN FACTOR VIII AND FACTOR VIII-LIKE PROTEINS
    Publication number: 20140221611
    Abstract: It is an object of the present invention to provide novel binding molecules for factor VIII and factor VIII-like proteins. Preferred binding molecules of the present invention exhibit not only distinct characteristics for binding of the target factor VIII polypeptides but also specific and desirable characteristics for release (elution) of the target polypeptides. Especially preferred binding molecules according to the invention are short polypeptide sequences, characterized by a stable loop structure.
    Type: Application
    Filed: August 14, 2013
    Publication date: August 7, 2014
    Applicant: DYAX CORP.
    Inventors: Jinan Yu, M. Daniel Potter, Brian D. Kelley, Jeffrey S. Deetz, James E. Booth
  • Binding molecules for human factor VIII and factor VIII-like proteins
    Patent number: 8535892
    Abstract: It is an object of the present invention to provide novel binding molecules for factor VIII and factor VIII-like proteins. Preferred binding molecules of the present invention exhibit not only distinct characteristics for binding of the target factor VIII polypeptides but also specific and desirable characteristics for release (elution) of the target polypeptides. Especially preferred binding molecules according to the invention are short polypeptide sequences, characterized by a stable loop structure.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: September 17, 2013
    Assignee: Dyax Corp.
    Inventors: Jinan Yu, M. Daniel Potter, Brian D. Kelley, Jeffrey S. Deetz, James E. Booth
  • METHOD OF WEAK PARTITIONING CHROMATOGRAPHY
    Publication number: 20120138537
    Abstract: This invention relates to methods of using weak partitioning chromatography for the purification of a product from a load fluid containing one or more impurities. Further, the invention relates to methods of weak partitioning chromatography defined by operating conditions which cause a medium to bind least 1 mg of product per mL of medium, or alternatively, defined by a partition coefficient of at least 0.1.
    Type: Application
    Filed: November 28, 2011
    Publication date: June 7, 2012
    Applicant: Wyeth LLC
    Inventors: Brian D. Kelley, James E. Booth, Paul Brown, Jon Coffman, Ranganathan Godavarti, Tim Iskra, Shujun Sun, Mary B. Switzer, Suresh Vunnum, Tianning Yu
  • BINDING MOLECULES FOR HUMAN FACTOR VIII AND FACTOR VIII-LIKE PROTEINS
    Publication number: 20120045819
    Abstract: It is an object of the present invention to provide novel binding molecules for factor VIII and factor VIII-like proteins. Preferred binding molecules of the present invention exhibit not only distinct characteristics for binding of the target factor VIII polypeptides but also specific and desirable characteristics for release (elution) of the target polypeptides. Especially preferred binding molecules according to the invention are short polypeptide sequences, characterized by a stable loop structure.
    Type: Application
    Filed: September 23, 2011
    Publication date: February 23, 2012
    Applicant: DYAX CORP.
    Inventors: Jinan Yu, M. Daniel Potter, Brian D. Kelley, Jeffrey S. Deetz, James E. Booth
  • Method of weak partitioning chromatography
    Patent number: 8067182
    Abstract: This invention relates to methods of using weak partitioning chromatography for the purification of a product from a load fluid containing one or more impurities. Further, the invention relates to methods of weak partitioning chromatography defined by operating conditions which cause a medium to bind least 1 mg of product per mL of medium, or alternatively, defined by a partition coefficient of at least 0.1.
    Type: Grant
    Filed: March 10, 2006
    Date of Patent: November 29, 2011
    Assignee: Wyeth LLC
    Inventors: Brian D. Kelley, James E. Booth, Paul Brown, Jon Coffman, Ranganathan Godavarti, Tim Iskra, Shujun Sun, Mary B. Switzer, Suresh Vunnum, Tianning Yu
  • Methods and compositions for purifying human factor VIII, factor VIII-like proteins or fragments thereof
    Patent number: 8058017
    Abstract: Provided herein are methods and compositions for purifying human factor VIII, human factor VIII-like peptide or fragments thereof. The methods comprise immobilizing a binding molecule for human factor VIII, human factor VIII-like protein or fragments thereof to a solid support, contacting the immobilized binding molecule with a solution containing the human factor VIII, human factor VIII-like protein or fragments thereof, and purifying the factor by separating the solution from the solid support.
    Type: Grant
    Filed: January 22, 2010
    Date of Patent: November 15, 2011
    Assignee: Dyax Corp.
    Inventors: Jinan Yu, M. Daniel Potter, Marilous Potter, legal representative, Brian D. Kelley, Jeffrey S. Deetz, James E. Booth
  • Binding Molecules for Human Factor VIII and Factor VIII-Like Proteins
    Publication number: 20100292440
    Abstract: It is an object of the present invention to provide novel binding molecules for factor VIII and factor VIII-like proteins. Preferred binding molecules of the present invention exhibit not only distinct characteristics for binding of the target factor VIII polypeptides but also specific and desirable characteristics for release (elution) of the target polypeptides. Especially preferred binding molecules according to the invention are short polypeptide sequences, characterized by a stable loop structure.
    Type: Application
    Filed: January 22, 2010
    Publication date: November 18, 2010
    Applicant: Dyax Corp.
    Inventors: Jinan Yu, M. Daniel Potter, Brian D. Kelley, Jeffrey S. Deetz, James E. Booth, Marilous Potter
  • Binding molecules for human factor VIII and factor VIII-like proteins
    Patent number: 7691565
    Abstract: It is an object of the present invention to provide novel binding molecules for factor VIII and factor VIII-like proteins. Preferred binding molecules of the present invention exhibit not only distinct characteristics for binding of the target factor VIII polypeptides but also specific and desirable characteristics for release (elution) of the target polypeptides. Especially preferred binding molecules according to the invention are short polypeptide sequences, characterized by a stable loop structure.
    Type: Grant
    Filed: January 31, 2006
    Date of Patent: April 6, 2010
    Assignee: Dyax Corp.
    Inventors: Jinan Yu, M. Daniel Potter, Marilous Potter, legal representative, Brian D. Kelley, Jeffrey S. Deetz, James E. Booth
  • Binding molecules for human factor VIII and factor VIII-like proteins
    Patent number: 7112438
    Abstract: It is an object of the present invention to provide novel binding molecules for factor VIII and factor VIII-like proteins. Preferred binding molecules of the present invention exhibit not only distinct characteristics for binding of the target factor VIII polypeptides but also specific and desirable characteristics for release (elution) of the target polypeptides. Especially preferred binding molecules according to the invention are short polypeptide sequences, characterized by a stable loop structure.
    Type: Grant
    Filed: October 15, 2002
    Date of Patent: September 26, 2006
    Assignee: Dyax Corp.
    Inventors: Jinan Yu, M. Daniel Potter, Brian D. Kelley, Jeffrey S. Deetz, James E. Booth
  • Binding molecules for human factor VIII and factor VIII-like proteins
    Publication number: 20030165822
    Abstract: It is an object of the present invention to provide novel binding molecules for factor VIII and factor VIII-like proteins. Preferred binding molecules of the present invention exhibit not only distinct characteristics for binding of the target factor VIII polypeptides but also specific and desirable characteristics for release (elution) of the target polypeptides. Especially preferred binding molecules according to the invention are short polypeptide sequences, characterized by a stable loop structure.
    Type: Application
    Filed: October 15, 2002
    Publication date: September 4, 2003
    Applicant: Dyax Corp.
    Inventors: Jinan Yu, M. Daniel Potter, Brian D. Kelley, Jeffrey S. Deetz, James E. Booth