Patents by Inventor James E. Bristol

James E. Bristol has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Haemophilus influenzae type b oxidized polysaccharide-outer membrane protein conjugate vaccine
    Patent number: 5192540
    Abstract: Immunogenic conjugates of a 38,000 daltons or 40,000 daltons outer membrane protein of H. influenzae type b and oxidized polyribosyl-ribitol-phosphate polysaccharide fragments of H. influenzae type b are disclosed. Vaccines containing the conjugates are disclosed as useful in immunizing against H. influenzae type b caused disease. Method for isolating and purifying the 38,000 daltons and 40,000 daltons outer membrane proteins and for preparing the oxidized polyribosyl-ribitol-phosphate polysaccharide fragments are also disclosed.
    Type: Grant
    Filed: February 21, 1989
    Date of Patent: March 9, 1993
    Assignee: American Cyanamid Company
    Inventors: Joseph S. Kuo, James E. Bristol