Patents by Inventor James E. Chomas

James E. Chomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220273920
    Abstract: Methods are provided for delivering a treatment therapy to treat an organ diagnosed with a disease state. The methods include delivering a first therapeutic agent into systemic circulation at a first flow rate, and delivering a second therapeutic agent directly into a vessel feeding the organ at a higher second flow rate than the first flow rate in a manner that prevents the second treatment agent from circulating systemically.
    Type: Application
    Filed: May 19, 2022
    Publication date: September 1, 2022
    Applicant: TriSalus Life Sciences, Inc.
    Inventors: Aravind Arepally, James E. Chomas, David Benjamin Jaroch, Patrick Charles McCain
  • Patent number: 11400263
    Abstract: A treatment system includes a guide sheath, and a catheter provided with a pressure-controlled element. The pressure-control element preferably includes an expanded configuration adapted to extend across a small feeder vessel branching from the splenic vein. The pressure-control element is positioned with the feeder vessel, and a therapeutic agent is delivered under pressure directly into the feeder vessel, where it is forced to penetrate deep into tissue. Pressure responsive elements for monitoring intravascular pressure are also provided to time delivery of the therapeutic agent for maximum uptake by the target organ. Methods for treating tissues and organs via vascular pathways are provided.
    Type: Grant
    Filed: January 15, 2018
    Date of Patent: August 2, 2022
    Assignee: TriSalus Life Sciences, Inc.
    Inventors: Aravind Arepally, James E. Chomas, Bryan Pinchuk, David Benjamin Jaroch
  • Patent number: 11337725
    Abstract: A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece. The device and method cut the fibrous structures under the skin that cause cellulite at an angle substantially parallel to the surface of the skin and replace these structures with a non-cellulite forming structure by deploying a highly fibrous mesh through a single needle hole to create a highly fibrous layer directly or through wound healing processes.
    Type: Grant
    Filed: October 25, 2019
    Date of Patent: May 24, 2022
    Assignee: Ulthera, Inc.
    Inventors: Robert L. Clark, III, James E. Chomas, Adnan I. Merchant, Ben F. Brian, III
  • Patent number: 11338117
    Abstract: A treatment system includes a dual lumen catheter system. The first lumen is open to systemic circulation. The second lumen is open to a target delivery location. In an embodiment, a pressure-control element is provided that includes an expanded configuration adapted to constrain delivery through the second lumen to the target delivery location. Methods for treating tissues and organs via vascular pathways are provided.
    Type: Grant
    Filed: May 7, 2019
    Date of Patent: May 24, 2022
    Assignee: TriSalus Life Sciences, Inc.
    Inventors: Aravind Arepally, James E. Chomas, Patrick Charles McCain, David Benjamin Jaroch, Jennifer D. Lucky
  • Patent number: 11213618
    Abstract: A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece. The device and method cut the fibrous structures under the skin that cause cellulite at an angle substantially parallel to the surface of the skin and replace these structures with a non-cellulite forming structure by deploying a highly fibrous mesh through a single needle hole to create a highly fibrous layer directly or through wound healing processes. A tool is provided to aspirate excess fluid and tissue from the treatment area.
    Type: Grant
    Filed: January 23, 2019
    Date of Patent: January 4, 2022
    Assignee: Ulthera, Inc.
    Inventors: Robert L. Clark, III, James E. Chomas, Adnan I. Merchant, Ben F. Brian, III
  • Publication number: 20210402088
    Abstract: A method is provided for infusing a therapeutic. The method includes providing a microvalve device having an inner catheter longitudinally displaceable relative to an outer catheter, and a filter valve coupled to the inner catheter adjacent the distal ends of the inner and outer catheters such that longitudinal displacement of the inner catheter relative to the outer catheter permits the filter valve to be reconfigured from a first configuration to a second configuration. The filter valve is advanced to a target location in via a blood vessel in which the filter valve is configured under tension. Then in an embodiment, the tension is released and the filter valve is placed under compression. Then the therapeutic agent is infused through the inner catheter and out of the orifice of the inner catheter beyond the filter valve.
    Type: Application
    Filed: September 14, 2021
    Publication date: December 30, 2021
    Applicant: TriSalus Life Sciences, Inc.
    Inventors: Bryan Pinchuk, James E. Chomas
  • Publication number: 20210369436
    Abstract: An endovascular system includes inner and outer catheters, a handle system operably coupled one end of the catheters, and a microvalve coupled to the other end of the catheters. The microvalve is constrained in a radially-collapsed closed configuration for advancement within a vessel to a treatment site. The handle system is operable to displace the inner and outer catheters portions relative to each other to move the microvalve between closed and open configurations. An indicator is provided to visually indicate the extent by which the microvalve is opened within the vessel.
    Type: Application
    Filed: June 23, 2021
    Publication date: December 2, 2021
    Applicant: Surefire Medical, Inc.
    Inventors: Leonard Pinchuk, James E. Chomas, John B. Martin, Aravind Arepally, Brett E. Naglreiter, Norman R. Weldon, Bryan M. Pinchuk
  • Publication number: 20210338262
    Abstract: Devices and methods for performing subcutaneous surgery in a minimally invasive manner are provided. The methods include application of reduced air pressure in a recessed area of a handpiece placed over a section of skin and drawing the section of skin and subcutaneous tissue into the recessed area. In a subsequent step a tool is inserted through a tool conduit in the handpiece and through the skin into the subcutaneous tissue, enabling the performance of the desired surgery. Common surgical procedures include dissection and ablation . The devices and methods can be directed at the treatment of skin conditions like atrophic scars, wrinkles, or other cosmetic issues, at treatments like or promoting wound healing or preventing hyperhidrosis, or can be used for creating space for various implants.
    Type: Application
    Filed: July 14, 2021
    Publication date: November 4, 2021
    Inventors: Robert L. Clark, III, James E. Chomas, Adnan I. Merchant, Ben F. Brian, III
  • Publication number: 20210338976
    Abstract: A method for delivering a therapeutic agent to a tumor through a target vessel includes delivering the therapeutic agent through a lumen of a catheter which has been coated or otherwise structured to reduce the wall shear stress during delivery of the immunotherapy and by generating turbulent flow during the delivery of the therapeutic agent.
    Type: Application
    Filed: July 14, 2021
    Publication date: November 4, 2021
    Applicant: Surefire Medical, Inc.
    Inventors: David Benjamin Jaroch, James E. Chomas
  • Patent number: 11135361
    Abstract: A method includes providing microvalve device having inner and outer catheters, and a filter valve attached to the distal end of the inner and outer catheters. Longitudinal displacement of the inner catheter relative to the outer catheter moves the filter valve from a non-deployed configuration to a deployed configuration. With the inner catheter longitudinally advanced a first amount relative to the outer catheter, the filter valve is in a reduced first diameter for advancement of a guidewire to a target location. Once the filter valve reaches the target location, the inner catheter is moved relative to the outer catheter such that the filter valve assumes a larger second diameter. A therapeutic agent is infused through the inner catheter and beyond the filter valve.
    Type: Grant
    Filed: May 3, 2018
    Date of Patent: October 5, 2021
    Assignee: Surefire Medical, Inc.
    Inventors: Bryan Pinchuk, James E. Chomas
  • Patent number: 11096708
    Abstract: Devices and methods for performing subcutaneous surgery in a minimally invasive manner are provided. The methods include application of reduced air pressure in a recessed area of a handpiece placed over a section of skin and drawing the section of skin and subcutaneous tissue into the recessed area. In a subsequent step a tool is inserted through a tool conduit in the handpiece and through the skin into the subcutaneous tissue, enabling the performance of the desired surgery. Common surgical procedures include dissection and ablation. The devices and methods can be directed at the treatment of skin conditions like atrophic scars, wrinkles, or other cosmetic issues, at treatments like or promoting wound healing or preventing hyperhidrosis, or can be used for creating space for various implants.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: August 24, 2021
    Assignee: Ulthera, Inc.
    Inventors: Robert L. Clark, III, James E. Chomas, Adnan I. Merchant, Ben F. Brian, III
  • Patent number: 11090460
    Abstract: A method for delivering an immunotherapy agent to a tumor includes advancing the delivery device into a vessel of a patient, and infusing the agent under pressure into the vessel to penetrate the tumor. The delivery device prevents reflux of the agent toward non-treatment sites.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: August 17, 2021
    Assignee: Surefire Medical, Inc.
    Inventors: David Benjamin Jaroch, James E. Chomas
  • Publication number: 20210113211
    Abstract: An endovascular treatment device for use in a vessel during a therapy procedure includes a catheter and a vessel occluder coupled to the catheter. The occluder includes a construction of elastic filaments that are fixed to the outer surface of the catheter. The filaments extend radially and distally outward from their proximal ends and then invert and are fixed back at the catheter proximal of the distal end of the catheter. The occluder can be elastically deformed to fit vessels of various sizes. The catheter includes a lumen through which a therapeutic agent is delivered beyond the occluder.
    Type: Application
    Filed: December 9, 2020
    Publication date: April 22, 2021
    Applicant: Surefire Medical, Inc.
    Inventors: Bryan Pinchuk, James E. Chomas, David Benjamin Jaroch
  • Publication number: 20210000582
    Abstract: An endovascular system includes inner and outer catheters, a handle system operably coupled one end of the catheters, and a microvalve coupled to the other end of the catheters. The microvalve is constrained in a radially-collapsed closed configuration for advancement within a vessel to a treatment site. The handle system is operable to displace the inner and outer catheters portions relative to each other to move the microvalve between closed and open configurations. An indicator is provided to visually indicate the extent by which the microvalve is opened within the vessel.
    Type: Application
    Filed: September 21, 2020
    Publication date: January 7, 2021
    Applicant: Surefire Medical, Inc.
    Inventors: James E. Chomas, Aravind Arepally, Bryan M. Pinchuk, Leonard Pinchuk
  • Publication number: 20200338265
    Abstract: A system includes a device having inner and outer catheters, and a filter valve attached to the distal end of the inner and outer catheters. Longitudinal displacement of the inner catheter relative to the outer catheter moves the filter valve from a non-deployed configuration to a deployed configuration. The device has a first configuration in which the distal end of the inner catheter is longitudinally advanced by a first distance relative to the distal end of the outer catheter and the filter valve assumes a stretched configuration, and a second configuration in which the distal end of the inner catheter is longitudinally advanced by a second distance relative to the distal end of the outer catheter to cause the filter valve to assume a diameter larger than in the stretched configuration.
    Type: Application
    Filed: May 14, 2020
    Publication date: October 29, 2020
    Applicant: Surefire Medical, Inc.
    Inventors: Bryan Pinchuk, James E. Chomas
  • Patent number: 10813739
    Abstract: An apparatus includes a delivery catheter having a deployable dynamic valve that dynamically opens and closes in response to relative fluid pressure thereabout, particularly while in an anatomical lumen. The valve is maintained in a collapsed configuration during introduction to a treatment site. The valve is adapted to automatically move from the collapsed configuration to a deployed configuration at the treatment site.
    Type: Grant
    Filed: November 6, 2017
    Date of Patent: October 27, 2020
    Assignee: Surefire Medical, Inc.
    Inventors: James E. Chomas, Leonard Pinchuk, John Martin, Aravind Arepally, Brett E. Naglreiter, Bryan M. Pinchuk
  • Patent number: 10780250
    Abstract: A treatment system includes a guide sheath, and a catheter provided with a pressure-controlled element. The pressure-control element preferably includes an expanded configuration adapted to extend across a small feeder vessel branching from the splenic vein. The pressure-control element is positioned with the feeder vessel, and a therapeutic agent is delivered under pressure directly into the feeder vessel, where it is forced to penetrate deep into tissue. Pressure responsive elements for monitoring intravascular pressure are also provided to time delivery of the therapeutic agent for maximum uptake by the target organ.
    Type: Grant
    Filed: September 13, 2017
    Date of Patent: September 22, 2020
    Assignee: Surefire Medical, Inc.
    Inventors: Aravind Arepally, David Benjamin Jaroch, Bryan Pinchuk, James E. Chomas
  • Publication number: 20200261695
    Abstract: Systems with pressure-responsive elements for monitoring intravascular pressure are also provided to time delivery of the therapeutic agent for maximum uptake by the target organ. Methods for treating tissues and organs via vascular pathways are provided.
    Type: Application
    Filed: February 21, 2020
    Publication date: August 20, 2020
    Applicant: Surefire Medical, Inc.
    Inventors: David Benjamin Jaroch, James E. Chomas, Bryan Pinchuk, Aravind Arepally
  • Publication number: 20200187971
    Abstract: A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece. The device and method cut the fibrous structures under the skin that cause cellulite at an angle substantially parallel to the surface of the skin and replace these structures with a non-cellulite forming structure by deploying a highly fibrous mesh through a single needle hole to create a highly fibrous layer directly or through wound healing processes.
    Type: Application
    Filed: December 6, 2019
    Publication date: June 18, 2020
    Inventors: Robert L. Clark, III, James E. Chomas, Adnan I. Merchant, Ben F. Brian, III
  • Publication number: 20200178976
    Abstract: An endovascular microvalve device for use in a vessel during a therapy procedure includes a catheter and a filter valve coupled to the catheters. The filter valve is dynamically reconfigurable to automatically block and permit fluid flow through a vessel based on a local fluid pressure conditions about the filter valve. In embodiments, the filter valve has a proximal end fixed to the catheter, and a distal end which may be movable over the catheter. The lumen of the inner catheter delivers a therapeutic agent beyond the valve. The device is used to provide a therapy in which a therapeutic agent is infused into an organ.
    Type: Application
    Filed: February 3, 2020
    Publication date: June 11, 2020
    Applicant: Surefire Medical, Inc.
    Inventors: Bryan Pinchuk, James E. Chomas, David Benjamin Jaroch