Abstract: Methods and systems of radiosurgical treatment include rotating one or both of a first gantry component and a second gantry component while transmitting a therapeutic treatment beam so as to deliver a therapeutic radiation dose to a target tissue of a patient from one or more arcs extending along a treatment sphere. The first gantry component is rotatable about a first axis and a second gantry component is interfaced with the first gantry component such that rotation of the first gantry component rotates both the first and second gantry components about the first axis. The second gantry component is independently rotatable about a second axis. The method includes coordinating movement of the first and second gantry components along the respective first and second axes so as to allow a trajectory of the therapeutic treatment beam to intersect the target tissue from multiple directions along the treatment sphere.

Abstract: Systems and methods for real-time target validation during radiation treatment therapy based on real-time target displacement and radiation dosimetry measurements.

Abstract: Systems and methods for real-time target validation during radiation treatment therapy based on real-time target displacement and radiation dosimetry measurements.

Abstract: A method performed by a medical device, includes: providing a permanent magnetic field by a permanent magnet; operating an electromagnet to provide a first electromagnetic field with a first electromagnetic field value; and operating the electromagnet to provide a second electromagnetic field with a second electromagnetic field value; wherein the first electromagnetic field and the permanent magnetic field forms a first total magnetic field with a first total magnetic field value, and wherein the second electromagnetic field and the permanent magnetic field forms a second total magnetic field with a second total magnetic field value; wherein the first total magnetic is formed when an electric field in an accelerator or an energy level of a particle beam has a first value, and wherein the second total magnetic field is formed when the electric field in the accelerator or the energy level of the particle beam has a second value.

Abstract: Systems and methods for real-time target validation during radiation treatment therapy based on real-time target displacement and radiation dosimetry measurements.

Abstract: A high-energy radiation treatment system can comprise a laser-driven accelerator system, a patient monitoring system, and a control system. The laser-driven accelerator system, such as a laser-driven plasma accelerator or a laser-driven dielectric microstructure accelerator, can be constructed to irradiate a patient disposed on a patient support. The patient monitoring system can be configured to detect and track a location or movement of a treatment volume within the patient. The control system can be configured to control the laser-driven accelerator system responsively to the location or movement of the treatment volume. The system can also include a beam control system, which generates a magnetic field that can affect the radiation beam and/or secondary electrons produced by the irradiation beam. In some embodiments, the beam control system and the patient monitoring system can comprise a magnetic resonance imaging system.

Abstract: Systems and methods for real-time target validation during radiation treatment therapy based on real-time target displacement and radiation dosimetry measurements.

Abstract: Systems and methods for real-time target validation during radiation treatment therapy based on real-time target displacement and radiation dosimetry measurements.

Abstract: A high-energy radiation treatment system can comprise a laser-driven accelerator system, a patient monitoring system, and a control system. The laser-driven accelerator system, such as a laser-driven plasma accelerator or a laser-driven dielectric microstructure accelerator, can be constructed to irradiate a patient disposed on a patient support. The patient monitoring system can be configured to detect and track a location or movement of a treatment volume within the patient. The control system can be configured to control the laser-driven accelerator system responsively to the location or movement of the treatment volume. The system can also include a beam control system, which generates a magnetic field that can affect the radiation beam and/or secondary electrons produced by the irradiation beam. In some embodiments, the beam control system and the patient monitoring system can comprise a magnetic resonance imaging system.

Abstract: A high-energy radiation treatment system can comprise a laser-driven accelerator system, a patient monitoring system, and a control system. The laser-driven accelerator system, such as a laser-driven plasma accelerator or a laser-driven dielectric microstructure accelerator, can be constructed to irradiate a patient disposed on a patient support. The patient monitoring system can be configured to detect and track a location or movement of a treatment volume within the patient. The control system can be configured to control the laser-driven accelerator system responsively to the location or movement of the treatment volume. The system can also include a beam control system, which generates a magnetic field that can affect the radiation beam and/or secondary electrons produced by the irradiation beam. In some embodiments, the beam control system and the patient monitoring system can comprise a magnetic resonance imaging system.

Abstract: Systems and methods for real-time target validation during radiation treatment therapy based on real-time target displacement and radiation dosimetry measurements.

Abstract: Systems and methods for real-time target validation during radiation treatment therapy based on real-time target displacement and radiation dosimetry measurements.

Abstract: A high-energy radiation treatment system can comprise a laser-driven accelerator system, a patient monitoring system, and a control system. The laser-driven accelerator system, such as a laser-driven plasma accelerator or a laser-driven dielectric microstructure accelerator, can be constructed to irradiate a patient disposed on a patient support. The patient monitoring system can be configured to detect and track a location or movement of a treatment volume within the patient. The control system can be configured to control the laser-driven accelerator system responsively to the location or movement of the treatment volume. The system can also include a beam control system, which generates a magnetic field that can affect the radiation beam and/or secondary electrons produced by the irradiation beam. In some embodiments, the beam control system and the patient monitoring system can comprise a magnetic resonance imaging system.

Abstract: A high-energy radiation treatment system can comprise a laser-driven accelerator system, a patient monitoring system, and a control system. The laser-driven accelerator system, such as a laser-driven plasma accelerator or a laser-driven dielectric microstructure accelerator, can be constructed to irradiate a patient disposed on a patient support. The patient monitoring system can be configured to detect and track a location or movement of a treatment volume within the patient. The control system can be configured to control the laser-driven accelerator system responsively to the location or movement of the treatment volume. The system can also include a beam control system, which generates a magnetic field that can affect the radiation beam and/or secondary electrons produced by the irradiation beam. In some embodiments, the beam control system and the patient monitoring system can comprise a magnetic resonance imaging system.

Abstract: An apparatus includes: a structure having a lumen for accommodating a beam (e.g., electron beam, proton beam, or a charged particle beam), wherein the structure is a component of a medical radiation machine having a target for interaction with the beam to generate radiation; and a first beam position monitor comprising a first electrode and a second electrode, the first electrode being mounted to a first side of the structure, the second electrode being mounted to a second side of the structure, the second side being opposite from the first side; wherein the first beam position monitor is located upstream with respect to the target.

Abstract: Systems and methods for real-time target validation during radiation treatment therapy based on real-time target displacement and radiation dosimetry measurements.

Abstract: A method performed by a medical device, includes: providing a permanent magnetic field by a permanent magnet; operating an electromagnet to provide a first electromagnetic field with a first electromagnetic field value; and operating the electromagnet to provide a second electromagnetic field with a second electromagnetic field value; wherein the first electromagnetic field and the permanent magnetic field forms a first total magnetic field with a first total magnetic field value, and wherein the second electromagnetic field and the permanent magnetic field forms a second total magnetic field with a second total magnetic field value; wherein the first total magnetic is formed when an electric field in an accelerator or an energy level of a particle beam has a first value, and wherein the second total magnetic field is formed when the electric field in the accelerator or the energy level of the particle beam has a second value.

Abstract: Systems and methods for real-time target validation during radiation treatment therapy based on real-time target displacement and radiation dosimetry measurements.

Abstract: A medical device includes: a base; a positioner coupled to the base; an accelerator coupled to the positioner, wherein the positioner is operable to rotate the accelerator relative to the base about at least two axes; and a power source coupled to the accelerator, the power source configured to provide microwave power for the accelerator, wherein a position of the power source relative to the base remains fixed during movement of the accelerator. A medical device includes: a base; a positioner coupled to the base; an accelerator coupled to the positioner; a power source configured to provide microwave power for the accelerator, wherein a position of the source relative to the base remains fixed during movement of the accelerator; and a waveguide for coupling the power source and the accelerator; wherein the waveguide has a first segment with a first cross section, the first cross section being a circular cross-section.

Abstract: A medical apparatus includes: a beam deflector having an electromagnet configured to provide a first magnetic field for deflecting a particle beam; and a current control configured to adjust a current of the electromagnet in correspondence with an energy level associated with an accelerator. A treatment planning method includes: defining control points in a treatment plan; setting up energy switching in one or more of the control points; and performing treatment optimization on the treatment plan based at least in part on the energy switching that is set up in the one or more of the control points. The medical apparatus also includes an energy adjuster configured to adjust the treatment energy so that the treatment energy has a first energy level when the beam output is at the first gantry angle, and a second energy level when the beam output is at the first gantry angle.