Abstract: A novel crystal form of ,&agr;-dimethyl-4-{1-hydroxy-4-{4-(hydroxydiphenylmethyl)-1-piperidinyl}butyl}benzeneacetic acid hydrochloride, processes for its preparation and its pharmaceutical use are disclosed.

Abstract: A novel crystal form of ,&agr;-dimethyl-4-{1-hydroxy-4-{4-(hydroxydiphenylmethyl)-1-piperidinyl}butyl}benzeneacetic acid hydrochloride, processes for its preparation and its pharmaceutical use are disclosed.

Abstract: A compound having nonlinear optical properties of the general formula:Ar.sup.1 CR.sup.1 .dbd.CR.sup.2 (Ar.sup.2 CR.sup.3 .dbd.CR.sup.4).sub.n Ar.sup.3 (I)wherein, n represents a whole number; R.sup.1, R.sup.1, R.sup.3 and R.sup.4 groups are independently selected from H, branched aliphatic, straight chain aliphatic, branched silane or straight chain silane; Ar.sup.1 and Ar.sup.3 are aromatic radicals having a substituent in at least one position adjacent to a site of attachment of the C.dbd.C double bond and having at least one electron withdrawing or electron donating substituent in at least one of the remaining positions; Ar.sup.2 is an aromatic radical having a substituent in at least one position adjacent to a site of attachment of the C.dbd.C double bond; with the proviso that the substituent in at least one position adjacent to the site of attachment of the C.dbd.C double bond and R.sup.1, R.sup.2, R.sup.3 and R.sup.4 groups are sufficiently large to cause Ar.sup.1, Ar.sup.2 and Ar.sup.