Patents by Inventor James E. Garrett
James E. Garrett has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 8600084Abstract: Computer-implemented methods are provided. One method includes determining an orientation of a display of a portable system. The method also includes altering an orientation of two speakers arranged along one side of the system based on the orientation of the display. Another method includes determining an orientation of a display of a portable system and determining an orientation of two speakers of the system based on the orientation of the display. If a current orientation of the two speakers differs from the determined orientation of the two speakers, the method includes altering the current orientation of the speakers such that they have the determined orientation. A portable system is also provided that includes means for determining an orientation of a display of the system. The system also includes means for altering an orientation of two speakers arranged along one side of the system based on the orientation of the display.Type: GrantFiled: November 9, 2004Date of Patent: December 3, 2013Assignee: Motion Computing, Inc.Inventor: James E. Garrett
-
Patent number: 7368432Abstract: The invention relates to relatively short conotoxin peptides, about 10-20 residues in length as described herein, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds. These conotoxin peptides have analgesic activity and are thus useful for treating or preventing pain.Type: GrantFiled: July 19, 2004Date of Patent: May 6, 2008Assignees: Xenome, Ltd., Cognetix, Inc.Inventors: J. Michael McIntosh, Baldomero M. Olivera, Lourdes J. Cruz, Gloria P. Corpuz, Robert M. Jones, James E. Garrett
-
Patent number: 7262280Abstract: The present invention features G-protein fusion receptors and chimeric GABAB receptors (GABABRs), nucleic acid encoding such receptors, and the use of such receptors and nucleic acid. G-protein fusion receptors comprise at least one domain from a CaR, an mGluR, and/or a GABAB receptor fused directly or through a linker to a guanine nucleotide-binding protein (G-protein). Chimeric GABABRs comprise at least one of a GABABR extracellular domain, a GABABR transmembrane domain, or a GABABR intracellular domain and one or more domains from a mGluR subtype 8 (mGluR8) and/or a CaR.Type: GrantFiled: October 3, 2000Date of Patent: August 28, 2007Assignee: NPS Pharmaceuticals, Inc.Inventors: Thomas M. Stormann, Lance G. Hammerland, Laura L. Storjohann, James G. Busby, James E. Garrett, Rachel T. Simin
-
Patent number: 7238513Abstract: Protein disulfide isomerase is a major component of Conus venom ducts. The invention relates to a protein disulfide isomerase (PDI) from Conus snails, a nucleic acid sequence encoding the Conus protein disulfide isomerase, and to methods for folding disulfide-rich peptides using a protein disulfide isomerase. Oxidative folding of conotoxin precursors, catalyzed by a PDI, was more efficient and decreased the number and concentration of transiently accumulated folding species. The PDI-assisted oxidative folding of conotoxins was also influenced by the propeptide relative to the mature peptide.Type: GrantFiled: August 31, 2005Date of Patent: July 3, 2007Assignees: University of Utah Research Foundation, Cognetix, Inc.Inventors: Grzegorz Bulaj, Baldomero M. Olivera, Olga Buczek, James E. Garrett, Ian Goodsell
-
Patent number: 7115708Abstract: The present invention is directed to ?-superfamily conotoxin peptides, derivatives or pharmaceutically acceptable salts thereof. The present invention is further directed to the use of this peptide, derivatives thereof and pharmaceutically acceptable salts thereof for the treatment of disorders associated with voltage-gated ion channels, ligand gated channels and other receptors. The invention is further directed to nucleic acid sequences encoding the ?-superfamily conotoxin peptides and encoding ?-superfamily conotoxin propeptides, as well as the ?-superfamily conotoxin propeptides.Type: GrantFiled: August 8, 2005Date of Patent: October 3, 2006Assignees: University of Utah Research Foundation, Cognetix, Inc.Inventors: Robert M. Jones, Baldomero M. Olivera, Maren Watkins, James E. Garrett
-
Publication number: 20040259794Abstract: The present invention is directed to the new &mgr;O-conopeptides, their coding sequences and their propeptides and to the use of &mgr;O-conopeptides as a local anesthetic for treating pain. The &mgr;O-conopeptides have long lasting anesthetic activity and are particularly useful for spinal anesthesia, either administered acutely for post-operative pain or via an intrathecal pump for severe chronic pain situations or for treatment of pain in epithelial tissue.Type: ApplicationFiled: July 9, 2004Publication date: December 23, 2004Applicants: Cognetix, Inc., University of Utah Research FoundationInventors: Baldomero M. Olivera, J. Michael McIntosh, R. Tyler McCabe, James E. Garrett, Richard T. Layer, John D. Wagstaff, Robert M. Jones
-
Publication number: 20040203132Abstract: Protein disulfide isomerase is a major component of Conus venom ducts. The invention relates to a protein disulfide isomerase (PDI) from Conus snails, a nucleic acid sequence encoding the Conus protein disulfide isomerase, and to methods for folding disulfide-rich peptides using a protein disulfide isomerase. Oxidative folding of conotoxin precursors, catalyzed by a PDI, was more efficient and decreased the number and concentration of transiently accumulated folding species. The PDI-assisted oxidative folding of conotoxins was also influenced by the propeptide relative to the mature peptide.Type: ApplicationFiled: February 27, 2004Publication date: October 14, 2004Applicant: Cognetix, Inc.Inventors: Grzegorz Bulaj, Baldomero M. Olivera, Olga Buczek, James E. Garrett, Ian Goodsell
-
Publication number: 20040192886Abstract: The present invention is to &mgr;-conopeptides, derivatives or pharmaceutically acceptable salts thereof. The present invention is further directed to the use of this peptide, derivatives thereof and pharmaceutically acceptable salts thereof for the treatment of disorders associated with voltage-gated sodium channels. Thus, the &mgr;-conopeptides or derivatives are useful as neuromuscular blocking agents, local anesthetic agents, analgesic agents and neuroprotective agents. The &mgr;-conopeptides are also useful for treating neuromuscular disorders. The invention is further directed to nucleic acid sequences encoding the &mgr;-conopeptides and encoding propeptides, as well as the propeptides.Type: ApplicationFiled: April 21, 2004Publication date: September 30, 2004Applicants: The University of Utah Research Foundation, Cognetix, Inc.Inventors: Baldomero M. Olivera, J. Michael McIntosh, James E. Garrett, Maren Watkins, Lourdes J. Cruz, Ki-Joon Shon, Richard B. Jacobsen, Robert M. Jones, G. Edward Cartier, Gregory S. Shen, John D. Wagstaff
-
Publication number: 20040176278Abstract: The present invention is directed to &bgr;-superfamily conotoxin peptides, derivatives or pharmaceutically acceptable salts thereof. The present invention is further directed to the use of this peptide, derivatives thereof and pharmaceutically acceptable salts thereof for the treatment of disorders associated with voltage-gated ion channels, ligand gated channels and other receptors. The invention is further directed to nucleic acid sequences encoding the &bgr;-superfamily conotoxin peptides and encoding &bgr;-superfamily conotoxin propeptides, as well as the &bgr;-superfamily conotoxin propeptides.Type: ApplicationFiled: May 5, 2004Publication date: September 9, 2004Applicants: University of Utah Research Foundation, Cognetix, Inc.Inventors: Robert M. Jones, Baldomero M. Olivera, Maren Watkins, James E. Garrett
-
Publication number: 20040163139Abstract: The present invention is relates to a &ggr;-carboxylase from Conus snails, a nucleic acid sequence encoding the Conus &ggr;-carboxylase and to a method for using the nucleic acid or protein sequences for preparing &ggr;-carboxylated proteins.Type: ApplicationFiled: March 1, 2004Publication date: August 19, 2004Applicants: Cognetix, Inc., University of Utah Research FoundationInventors: James E. Garrett, Pradip K. Bandyopadhyay
-
Patent number: 6767896Abstract: The invention relates to relatively short conotoxin peptides, about 10-20 residues in length as described herein, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds. These conotoxin peptides have analgesic activity and are thus useful for treating or preventing pain.Type: GrantFiled: May 26, 2000Date of Patent: July 27, 2004Assignees: Cognetix, Inc., University of Utah Research FoundationInventors: J. Michael McIntosh, Baldomero M. Olivera, Lourdes J. Cruz, Gloria P. Corpuz, Robert M. Jones, James E. Garrett
-
Publication number: 20040132663Abstract: The invention relates to &ohgr;-conopeptides, derivatives or pharmaceutically acceptable salts thereof, and uses thereof, including the treatment of neurologic and psychiatric disorders, such as anticonvulsant agents, as neuroprotective agents, as cardiovascular agents or for the management of pain. The invention further relates to nucleic acid sequences encoding the conopeptides and encoding propeptides, as well as the propeptides.Type: ApplicationFiled: January 29, 2004Publication date: July 8, 2004Applicants: University of Utah Research Foundation, Cognetix, Inc.Inventors: Baldomero M. Olivera, J. Michael McIntosh, Maren Watkins, James E. Garrett, Ki-Joon Shon, Richard B. Jacobsen, Robert M. Jones, G. Edward Cartier
-
Patent number: 6727226Abstract: The present invention is to &mgr;-conopeptides, derivatives or pharmaceutically acceptable salts thereof. The present invention is further directed to the use of this peptide, derivatives thereof and pharmaceutically acceptable salts thereof for the treatment of disorders associated with voltage-gated sodium channels. Thus, the &mgr;-conopeptides or derivatives are useful as neuromuscular blocking agents, local anesthetic agents, analgesic agents and neuroprotective agents. The &mgr;-conopeptides are also useful for treating neuromuscular disorders. The invention is further directed to nucleic acid sequences encoding the &mgr;-conopeptides and encoding propeptides, as well as the propeptides.Type: GrantFiled: July 23, 2001Date of Patent: April 27, 2004Assignees: University of Utah Research Foundation, Cognetix, Inc.Inventors: Baldomero M. Olivera, J. Michael McIntosh, James E. Garrett, Lourdes J. Cruz, Robert M. Jones, G. Edward Cartier, John D. Wagstaff
-
Publication number: 20030170222Abstract: The present invention is directed to &bgr;-superfamily conotoxin peptides, derivatives or pharmaceutically acceptable salts thereof. The present invention is further directed to the use of this peptide, derivatives thereof and pharmaceutically acceptable salts thereof for the treatment of disorders associated with voltage-gated ion channels, ligand gated channels and other receptors. The invention is further directed to nucleic acid sequences encoding the &bgr;-superfamily conotoxin peptides and encoding &bgr;-superfamily conotoxin propeptides, as well as the &bgr;-superfamily conotoxin propeptides.Type: ApplicationFiled: January 29, 2002Publication date: September 11, 2003Applicant: University of Utah Research FoundationInventors: Robert M. Jones, Baldomero M. Olivera, Maren Watkins, James E. Garrett
-
Publication number: 20030166560Abstract: The present invention is directed to P-superfamily conopeptides, to DNA encoding precursors of the P-superfamily conopeptides and to the precursor peptides.Type: ApplicationFiled: January 30, 2003Publication date: September 4, 2003Inventors: David Hooper, James E. Garrett, Gloria P. Corpuz, Lourdes J. Cruz, Baldomero M. Olivera, J. Michael McIntosh, Robert M. Jones
-
Publication number: 20030144210Abstract: The invention relates to &ggr;-carboxyglutamate containing conopeptides, derivatives or pharmaceutically acceptable salts thereof, and uses thereof, including the treatment of neurologic and psychiatric disorders, such as anticonvulsant agents, as neuroprotective agents or for the management of pain. The invention further relates to nucleic acid sequences encoding the conopeptides and encoding propeptides, as well as the propeptides.Type: ApplicationFiled: July 31, 2002Publication date: July 31, 2003Inventors: Baldomero M. Olivera, J. Michael McIntosh, James E. Garrett, Craig S. Walker, Maren Watkins, Robert M. Jones
-
Publication number: 20030119731Abstract: The invention relates to &ohgr;-conopeptides, derivatives or pharmaceutically acceptable salts thereof, and uses thereof, including the treatment of neurologic and psychiatric disorders, such as anticonvulsant agents, as neuroprotective agents, as cardiovascular agents or for the management of pain. The invention further relates to nucleic acid sequences encoding the conopeptides and encoding propeptides, as well as the propeptides.Type: ApplicationFiled: July 23, 2001Publication date: June 26, 2003Applicant: UNIVERSITY OF UTAH RESEARCH FOUNDATIONInventors: Baldomero M. Olivera, J. Michael McIntosh, Maren Watkins, James E. Garrett, Ki-Joon Shon, Richard B. Jacobsen, Robert M. Jones, G. Edward Cartier
-
Publication number: 20030109670Abstract: The present invention is directed to conotoxin peptides, derivatives or pharmaceutically acceptable salts thereof. The present invention is further directed to the use of this peptide, derivatives thereof and pharmaceutically acceptable salts thereof for the treatment of disorders associated with voltage-gated ion channels, voltage-gated ligand channels and/or receptors. The invention is further directed to nucleic acid sequences encoding the conotoxin peptides and encoding propeptides, as well as the propeptides.Type: ApplicationFiled: February 11, 2002Publication date: June 12, 2003Applicant: University of Utah Research FoundationInventors: Baldomero M. Olivera, J. Michael McIntosh, Maren Watkins, James E. Garrett, Lourdes J. Cruz, Michelle Grilley, Robert A. Schoenfeld, Craig S. Walker, Reshma P. Shetty, Robert M. Jones
-
Publication number: 20030096361Abstract: The present invention is relates to a &ggr;-carboxylase from Conus snails, a nucleic acid sequence encoding the Conus &ggr;-carboxylase and to a method for using the nucleic acid or protein sequences for preparing &ggr;-carboxylated proteins.Type: ApplicationFiled: August 7, 2002Publication date: May 22, 2003Applicant: Cognetix, Inc.Inventors: James E. Garrett, Pradip K. Bandypadhyay
-
Publication number: 20030065138Abstract: The invention relates to linear &ggr;-carboxyglutamate rich conotoxins, derivatives or pharmaceutically acceptable salts thereof, and uses thereof, including the treatment of neurologic and psychiatric disorders, such as anticonvulsant agents, as neuroprotective agents or for the management of pain. The invention further relates to nucleic acid sequences encoding the conopeptides and encoding propeptides, as well as the propeptides.Type: ApplicationFiled: March 7, 2002Publication date: April 3, 2003Applicant: University of Utah Research FoundationInventors: Baldomero M. Olivera, J. Michael McIntosh, James E. Garrett, Craig S. Walker, Maren Watkins, Robert M. Jones