Abstract: The invention is directed to a method of and machine for loading a scroll of film and take-up spool into a cartridge and assembling and sealing the cartridge. It includes the steps of supplying a web of film and backing paper to a scrolling mechanism and winding the webs into a scroll. A single guide track guides and assists in advancing the webs of film and backing paper to a winding spindle. Severing mechanisms are located along the guide track to cut the webs into the desired lengths. The winding spindle is engaged by the webs for scrolling within a socket on a first transport carrier. When scrolling is complete the spindle is withdrawn and the scroll is retained in the socket. An ultrasonic securing device is used to secure a free end of the scroll to a take-up spool carried in another socket of the carrier.