Patents by Inventor James E. K. Hildreth

James E. K. Hildreth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Okra-derived antiviral composition and uses thereof
    Patent number: 12343365
    Abstract: Artificial cervical fluid is disclosed that contains a mucilaginous extract from the okra plant. The mucilaginous extract can be produced using a hot aqueous extractant or cold extraction process followed by separation of larger particles from the extract. The extract finds many uses, for example as a sperm storage medium, a sperm freezing medium, a sexual lubricant, an artificial insemination medium, an in vitro fertilization medium, and methods for treating and/or preventing infection, replication, and transmission of viruses, such as sexually transmitted viruses.
    Type: Grant
    Filed: March 21, 2021
    Date of Patent: July 1, 2025
    Inventors: Anthony E. Archibong, Bindong Liu, G. William Bates, Elochukwu J. Ezekakpu, Lorin W. Simon, James E. K. Hildreth
  • Okra as a substitute for cervical mucus
    Patent number: 11986504
    Abstract: Artificial cervical fluid is disclosed that contains a mucilaginous extract from the okra plant. The mucilaginous extract can be produced using a hot aqueous extractant or cold extraction process followed by separation of larger particles from the extract. The extract finds many uses, for example as a sperm storage medium, a sperm freezing medium, a sexual lubricant, an artificial insemination medium, and an in vitro fertilization medium.
    Type: Grant
    Filed: December 28, 2021
    Date of Patent: May 21, 2024
    Assignee: Meharry Medical College
    Inventors: Anthony E. Archibong, G. William Bates, Elochukwu J. Ezekakpu, Lorin W. Simon, James E. K. Hildreth
  • Okra as a substitute for cervical mucus
    Patent number: 11241466
    Abstract: Artificial cervical fluid is disclosed that contains a mucilaginous extract from the okra plant. The mucilaginous extract can be produced using a hot aqueous extractant or cold extraction process followed by separation of larger particles from the extract. The extract finds many uses, for example as a sperm storage medium, a sperm freezing medium, a sexual lubricant, an artificial insemination medium, and an in vitro fertilization medium.
    Type: Grant
    Filed: March 6, 2019
    Date of Patent: February 8, 2022
    Inventors: Anthony E. Archibong, G. William Bates, Elochukwu J. Ezekakpu, Lorin W. Simon, James E. K. Hildreth
  • Channel forming toxins as antiviral agents
    Patent number: 6495315
    Abstract: The infectivity of a population of enveloped viruses which comprise a glycosylphosphatidylinositol-anchored protein in their membrane can be reduced by employing certain toxins such as aerolysin, alpha toxin of Clostridium septicum, or enterolobin. Toxins which bind to glycosylphosphatidylinositol-anchored proteins inactivate such viruses. The toxins can be used to produce attenuated viral vaccines, to purge blood products, cells, or tissues of such viruses, and to detect viruses in samples.
    Type: Grant
    Filed: January 12, 2001
    Date of Patent: December 17, 2002
    Assignee: The Johns Hopkins University
    Inventors: James E. K. Hildreth, Dzung H. Nguyen, James Thomas Buckley