Abstract: This invention relates to a class of pyrrolidine compounds of formula (I), and pharmaceutically acceptable derivatives thereof, to their use in medicine, to compositions containing them, and to processes for their preparation. It also relates to intermediates used in the preparation of such compounds and derivatives. In particular the compounds of formula (I) are useful for the treatment of EP2-mediated conditions, such as endometriosis, uterine fibroids (leiomyomata), menorrhagia, adenomyosis, primary and secondary dysmenorrhoea (including symptoms of dyspareunia, dyschexia and chronic pelvic pain), chronic pelvic pain syndrome.

Abstract: This invention relates to a class of pyrrolidine compounds of formula (I), and pharmaceutically acceptable derivatives thereof, to their use in medicine, to compositions containing them, and to processes for their preparation. It also relates to intermediates used in the preparation of such compounds and derivatives. In particular the compounds of formula (I) are useful for the treatment of EP2-mediated conditions, such as endometriosis, uterine fibroids (leiomyomata), menorrhagia, adenomyosis, primary and secondary dysmenorrhoea (including symptoms of dyspareunia, dyschexia and chronic pelvic pain), chronic pelvic pain syndrome.

Abstract: A versatile portable support for cameras, spotting scopes, and other devices is shown secured to a collateral support object (tree). A rope or the like is attached to a central hub member (FIG. 4), and encircled about a collateral support object one or more times, and then tightly placed in rope gripping clamps (FIG. 9). An optical device attachment assembly (FIG. 14), is removably coupled to an arm member (FIG. 10), which rotably and extendably supports cameras, spotting scopes, and other devices. My support is also shown configured so as to stand, tripod-like, on a generally horizontal surface. A central hub member (FIG. 4), houses an arm member hub (FIG. 11) and an elongated leg hub member (FIG. 7). Rotation of cam lock knob (FIG. 5) , disengages central hub member (FIG. 4), enabling rotational adjustment of tree leg assembly (FIG. 8), plural elongated leg assembly (FIG. 6), and arm member (FIG. 10), about central rotational axis 69 of central hub member (FIG. 4).

Abstract: The efficiency of a microwave oven of a conventional two-source configuration and energy level is increased by providing the oven with a container for housing a refractory material to be treated. The container is formed of top and bottom walls transparent to microwaves while the sidewalls, in a circular configuration, are formed of a nonmetallic material opaque to microwave radiation reflecting the radiation penetrating the top and bottom walls radially inwardly into the center of the container wherein a casket of heat-insulating material is provided for housing the material to be heat treated. The reflection of the microwave radiation from the sidewalls increases the concentration of the microwaves upon the material being heat treated while the casket retains the heat to permit the heating of the material to a substantially higher temperature than achieveable in the oven without the container.