Patents by Inventor James E. Ring
James E. Ring has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7783098Abstract: A method including acquiring images of medical slides at a plurality of different focus positions, determining a position which produces a maximum value of pixel values relative to a pixel value mean, wherein said determining comprises using a pixel value mean as a coarse estimate of coarse focus position, and subsequently refining said coarse focus position to find a fine focus position, and wherein said refining comprises fitting to a polynomial, and using a specified portion of the polynomial as a fine estimate of focus position, and producing a focus control signal that is related to said maximum value to control a focus position.Type: GrantFiled: August 29, 2008Date of Patent: August 24, 2010Assignee: Carl Zeiss MicroImaging GmbHInventors: James W. Douglass, Thomas J. Riding, James E. Ring, Gina McLaren, William J. Decker, Robert T. Ellis
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Patent number: 7558415Abstract: A method, system, and apparatus are provided for automated light microscopic for detection of proteins associated with cell proliferative disorders.Type: GrantFiled: February 13, 2007Date of Patent: July 7, 2009Assignee: Carl Zeiss MicroImaging AIS, Inc.Inventors: Gina McLaren, Robert Ellis, James W. Douglass, Thomas J. Riding, James E. Ring
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Publication number: 20090060303Abstract: A method including acquiring images of medical slides at a plurality of different focus positions, determining a position which produces a maximum value of pixel values relative to a pixel value mean, wherein said determining comprises using a pixel value mean as a coarse estimate of coarse focus position, and subsequently refining said coarse focus position to find a fine focus position, and wherein said refining comprises fitting to a polynomial, and using a specified portion of the polynomial as a fine estimate of focus position, and producing a focus control signal that is related to said maximum value to control a focus position.Type: ApplicationFiled: August 29, 2008Publication date: March 5, 2009Applicant: Carl Zeiss Microlmaging AIS, Inc.Inventors: James W. Douglass, Thomas J. Riding, James E. Ring, Gina McLaren, William J. Decker, Robert T. Ellis
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Publication number: 20080258061Abstract: An electronic microscope system including a processor, a movable stage movable in two orthogonal directions under control of the processor, the movable stage including at least one part that determines a current position of the movable stage, a microscope part, which magnifies a sample on the movable stage, an electronic camera part, which obtains an image of a magnified sample at a specified position controlled by the movable stage, and at least one vibration isolation mount, coupled to the stage and isolating vibration between the movable stage and the microscope part.Type: ApplicationFiled: April 14, 2008Publication date: October 23, 2008Applicant: Carl Zeiss Microlmaging AIS, Inc.Inventors: James W. Douglass, Thomas J. Riding, James E. Ring
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Patent number: 7428325Abstract: A method and apparatus for automated cell analysis of biological specimens automatically scans at a low magnification to acquire images which are analyzed to determine candidate cell objects of interest. The low magnification images are converted from a first color space to a second color space. The color space converted image is then filtered. The candidate interest pixels are morphologically processed and compared to blob parameters to identify candidate objects of interest which correspond to cells or other structures relevant to medical diagnosis of the biological specimen. The location coordinates of the objects of interest are stored and additional images of the candidate cell objects are acquired at high magnification.Type: GrantFiled: March 13, 2007Date of Patent: September 23, 2008Assignee: Carl Zeiss MicroImaging AIS, Inc.Inventors: James W. Douglass, Thomas J. Riding, James E. Ring, Gina McLaren, William J. Decker, Robert T. Ellis
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Patent number: 7359548Abstract: A method and apparatus for automated cell analysis of biological specimens automatically scans at a low magnification to acquire images which are analyzed to determine candidate cell objects of interest. The low magnification images are converted from a first color space to a second color space. The color space converted image is then low pass filtered and compared to a threshold to remove artifacts and background objects from the candidate object of interest pixels of the color converted image. The candidate object of interest pixels are morphologically processed to group candidate object of interest pixels together into groups which are compared to blob parameters to identify candidate objects of interest which correspond to cells or other structures relevant to medical diagnosis of the biological specimen. The location coordinates of the objects of interest are stored and additional images of the candidate cell objects are acquired at high magnification.Type: GrantFiled: November 7, 2006Date of Patent: April 15, 2008Assignee: Carl Zeiss MicroImaging AIS, Inc.Inventors: James W. Douglass, Thomas J. Riding, James E. Ring
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Patent number: 7177454Abstract: A method, system, and apparatus are provided for automated light microscopic for detection of proteins associated with cell proliferative disorders.Type: GrantFiled: February 3, 2003Date of Patent: February 13, 2007Assignee: Clarient, Inc.Inventors: Gina McLaren, Robert Ellis, James W. Douglass, Thomas J. Riding, James E. Ring
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Patent number: 7133545Abstract: A method and apparatus for automated cell analysis of biological specimens automatically scans at a low magnification to acquire images which are analyzed to determine candidate cell objects of interest. The low magnification images are converted from a first color space to a second color space. The color space converted image is then low pass filtered and compared to a threshold to remove artifacts and background objects from the candidate object of interest pixels of the color converted image. The candidate object of interest pixels are morphologically processed to group candidate object of interest pixels together into groups which are compared to blob parameters to identify candidate objects of interest which correspond to cells or other structures relevant to medical diagnosis of the biological specimen. The location coordinates of the objects of interest are stored and additional images of the candidate cell objects are acquired at high magnification.Type: GrantFiled: April 26, 2005Date of Patent: November 7, 2006Assignee: Clarient, Inc.Inventors: James W. Douglass, Thomas J. Riding, James E. Ring
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Patent number: 6920239Abstract: A method and apparatus for automated cell analysis of biological specimens automatically scans at a low magnification to acquire images which are analyzed to determine candidate cell objects of interest. The low magnification images are converted from a first color space to a second color space. The color space converted image is then low pass filtered and compared to a threshold to remove artifacts and background objects from the candidate object of interest pixels of the color converted image. The candidate object of interest pixels are morphologically processed to group candidate object of interest pixels together into groups which are compared to blob parameters to identify candidate objects of interest which correspond to cells or other structures relevant to medical diagnosis of the biological specimen. The location coordinates of the objects of interest are stored and additional images of the candidate cell objects are acquired at high magnification.Type: GrantFiled: March 31, 2003Date of Patent: July 19, 2005Assignee: ChromaVision Medical Systems, Inc.Inventors: James W. Douglass, Thomas J. Riding, James E. Ring
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Publication number: 20040066960Abstract: A method, system, and apparatus are provided for automated light microscopic for detection of proteins associated with cell proliferative disorders.Type: ApplicationFiled: February 3, 2003Publication date: April 8, 2004Applicant: ChromaVision Medical Systems, Inc., a California corporationInventors: Gina McLaren, Robert Ellis, James W. Douglass, Thomas J. Riding, James E. Ring
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Publication number: 20030228038Abstract: A method and apparatus for automated cell analysis of biological specimens automatically scans at a low magnification to acquire images which are analyzed to determine candidate cell objects of interest. The low magnification images are converted from a first color space to a second color space. The color space converted image is then low pass filtered and compared to a threshold to remove artifacts and background objects from the candidate object of interest pixels of the color converted image. The candidate object of interest pixels are morphologically processed to group candidate object of interest pixels together into groups which are compared to blob parameters to identify candidate objects of interest which correspond to cells or other structures relevant to medical diagnosis of the biological specimen. The location coordinates of the objects of interest are stored and additional images of the candidate cell objects are acquired at high magnification.Type: ApplicationFiled: March 31, 2003Publication date: December 11, 2003Applicant: Chroma Vision Medical Systems, Inc., a California CorporationInventors: James W. Douglass, Thomas J. Riding, James E. Ring
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Patent number: 6553135Abstract: A method and apparatus for automated cell analysis of biological specimens automatically scans at a low magnification to acquire images which are analyzed to determine candidate cell objects of interest. The low magnification images are converted from a first color space to a second color space. The color space converted image is then low pass filtered and compared to a threshold to remove artifacts and background objects from the candidate object of interest pixels of the color converted image. The candidate object of interest pixels are morphologically processed to group candidate object of interest pixels together into groups which are compared to blob parameters to identify candidate objects of interest which correspond to cells or other structures relevant to medical diagnosis of the biological specimen. The location coordinates of the objects of interest are stored and additional images of the candidate cell objects are acquired at high magnification.Type: GrantFiled: February 14, 2000Date of Patent: April 22, 2003Assignee: Chromavision Medical Systems, Inc.Inventors: James W. Douglass, Thomas J. Riding, James E. Ring
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Patent number: 6215892Abstract: A method and apparatus for automated cell analysis of biological specimens automatically scans at a low magnification to acquire images which are analyzed to determine candidate cell objects of interest. The low magnification images are converted from a first color space to a second color space. The color space converted image is then low pass filtered and compared to a threshold to remove artifacts and background objects from the candidate object of interest pixels of the color converted image. The candidate object of interest pixels are morphologically processed to group candidate object of interest pixels together into groups which are compared to blob parameters to identify candidate objects of interest which correspond to cells or other structures relevant to medical diagnosis of the biological specimen. The location coordinates of the objects of interest are stored and additional images of the candidate cell objects are acquired at high magnification.Type: GrantFiled: November 27, 1996Date of Patent: April 10, 2001Assignee: ChromaVision Medical Systems, Inc.Inventors: James W. Douglass, Thomas J. Riding, James E. Ring