Patents by Inventor James E. Rozzelle

James E. Rozzelle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160312195
    Abstract: The invention provides novel nucleic acid polymerases from strains GK24 and RQ-1 of Thermus thermophilus, and nucleic acids encoding those polymerases, as well as methods for using the polymerases and nucleic acids.
    Type: Application
    Filed: July 13, 2016
    Publication date: October 27, 2016
    Inventors: James E. ROZZELLE, Elena V. Bolchakova
  • Patent number: 9382522
    Abstract: The invention provides nucleic acids and polypeptides for a nucleic acid polymerase from a thermophilic organism, Thermus scotoductus. The invention also provides methods for using these nucleic acids and polypeptides.
    Type: Grant
    Filed: August 19, 2009
    Date of Patent: July 5, 2016
    Assignee: APPLIED BIOSYSTEMS, LLC
    Inventors: Elena V. Bolchakova, James E. Rozzelle
  • Patent number: 8318469
    Abstract: The invention provides nucleic acids and polypeptides for nucleic acid polymerases from a thermophilic organism, Thermus brockianus. The invention also provides methods for using these nucleic acids and polypeptides.
    Type: Grant
    Filed: December 13, 2005
    Date of Patent: November 27, 2012
    Assignee: Applied Biosystems, LLC
    Inventors: James E. Rozzelle, Elena V. Bolchakova
  • Publication number: 20120082979
    Abstract: Methods, reagents, and kits for (mis)ligating oligonucleotide probes or for identifying at least one target nucleotide are disclosed. One can enhance the generation of misligation product using a ligase under reaction conditions and with reagents where that particular ligase is prone to misligation. Alternatively, one can decrease or avoid generating misligation products using a particular ligase under reaction conditions and using reagents where that ligase is at least less prone to misligation. In certain embodiments, the recombinant ligase from Archaeoglobus fulgidus (Afu) is employed due to its unique misligation properties.
    Type: Application
    Filed: July 18, 2011
    Publication date: April 5, 2012
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Achim E. KARGER, James E. Rozzelle, Chien-Wei Chang, Elena V. Bolchakova
  • Publication number: 20110177497
    Abstract: The invention provides novel nucleic acid polymerases from strains GK24 and RQ-1 of Thermus thermophilus, and nucleic acids encoding those polymerases, as well as methods for using the polymerases and nucleic acids.
    Type: Application
    Filed: October 14, 2010
    Publication date: July 21, 2011
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: James E. Rozzelle, Elena BOLCHAKOVA
  • Publication number: 20100086970
    Abstract: The invention provides nucleic acids and polypeptides for a nucleic acid polymerase from a thermophilic organism, Thermus scotoductus. The invention also provides methods for using these nucleic acids and polypeptides.
    Type: Application
    Filed: August 19, 2009
    Publication date: April 8, 2010
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Elena V. BOLCHAKOVA, James E. Rozzelle
  • Publication number: 20090311709
    Abstract: Methods, reagents, and kits for (mis)ligating oligonucleotide probes or for identifying at least one target nucleotide are disclosed. One can enhance the generation of misligation product using a ligase under reaction conditions and with reagents where that particular ligase is prone to misligation. Alternatively, one can decrease or avoid generating misligation products using a particular ligase under reaction conditions and using reagents where that ligase is at least less prone to misligation. In certain embodiments, the recombinant ligase from Archaeoglobus fulgidus (Afu) is employed due to its unique misligation properties.
    Type: Application
    Filed: July 14, 2009
    Publication date: December 17, 2009
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Achim E. KARGER, James E. Rozzelle, Chien-Wei Chang, Elena V. Bolchakova
  • Publication number: 20090209008
    Abstract: The invention provides novel nucleic acid polymerases from strains GK24 and RQ-1 of Thermus thermophilus, and nucleic acids encoding those polymerases, as well as methods for using the polymerases and nucleic acids.
    Type: Application
    Filed: August 18, 2008
    Publication date: August 20, 2009
    Applicant: APPLIED BIOSYSTEMS INC.
    Inventors: JAMES E. ROZZELLE, ELENA V. BOLCHAKOVA
  • Patent number: 7422872
    Abstract: The invention provides novel nucleic acid polymerases from strains GK24 and RQ-1 of Thermus thermophilus, and nucleic acids encoding those polymerases, as well as methods for using the polymerases and nucleic acids.
    Type: Grant
    Filed: December 11, 2006
    Date of Patent: September 9, 2008
    Assignee: Applied Biosystems Inc.
    Inventors: James E. Rozzelle, Elena V. Bolchakova
  • Patent number: 7148340
    Abstract: The invention provides novel nucleic acid polymerases from strains GK24 and RQ-1 of Thermus thermophilus, and nucleic acids encoding those polymerases, as well as methods for using the polymerases and nucleic acids.
    Type: Grant
    Filed: November 22, 2002
    Date of Patent: December 12, 2006
    Assignee: Applera Corporation
    Inventors: James E. Rozzelle, Elena V. Bolchakova
  • Patent number: 7052877
    Abstract: The invention provides nucleic acids and polypeptides for nucleic acid polymerases from a thermophilic organism, Thermus brockianus. The invention also provides methods for using these nucleic acids and polypeptides.
    Type: Grant
    Filed: November 22, 2002
    Date of Patent: May 30, 2006
    Assignee: Applera Corporation
    Inventors: James E. Rozzelle, Elena V. Bolchakova
  • Publication number: 20030228589
    Abstract: Compositions comprising at least two polymerases are provided. Methods for producing primer extension products using at least two polymerases are also provided. Kits for producing primer extension products comprising at least two polymerases are also provided.
    Type: Application
    Filed: February 11, 2003
    Publication date: December 11, 2003
    Inventors: Diane R. Bond-Nutter, Cheryl R. Heiner, James E. Rozzelle
  • Publication number: 20030211593
    Abstract: The invention provides novel nucleic acid polymerases from strains GK24 and RQ-1 of Thermus thermophilus, and nucleic acids encoding those polymerases, as well as methods for using the polymerases and nucleic acids.
    Type: Application
    Filed: November 22, 2002
    Publication date: November 13, 2003
    Applicant: APPLERA CORPORATION
    Inventors: James E. Rozzelle, Elena V. Bolchakova
  • Publication number: 20030198978
    Abstract: The invention provides nucleic acids and polypeptides for nucleic acid polymerases from a thermophilic organism, Thermus brockianus. The invention also provides methods for using these nucleic acids and polypeptides.
    Type: Application
    Filed: November 22, 2002
    Publication date: October 23, 2003
    Applicant: APPLERA CORPORATION
    Inventors: James E. Rozzelle, Elena V. Bolchakova
  • Publication number: 20030194726
    Abstract: The invention provides nucleic acids and polypeptides for a nucleic acid polymerase enzyme from a thermophilic organism, Thermus oshimai. The invention also provides methods for using these nucleic acids and polypeptides.
    Type: Application
    Filed: November 22, 2002
    Publication date: October 16, 2003
    Applicant: APPLERA CORPORATION
    Inventors: Elena V. Bolchakova, James E. Rozzelle
  • Publication number: 20030175756
    Abstract: The invention provides nucleic acids and polypeptides for a nucleic acid polymerase from a thermophilic organism, Thermus igniterrae. The invention also provides methods for using these nucleic acids and polypeptides.
    Type: Application
    Filed: November 22, 2002
    Publication date: September 18, 2003
    Applicant: APPLERA CORPORATION
    Inventors: Elena V. Bolchakova, James E. Rozzelle