Patents by Inventor James E. Simon

James E. Simon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180116144
    Abstract: The invention provides seed and plants of catnip hybrid ‘CR9’. The invention thus relates to the plants, seeds, and tissue cultures of catnip hybrid ‘CR9’, and to methods for producing a catnip plant of the present invention by crossing such plants with themselves or with another catnip plant, such as a plant of another genotype, variety, or cultivar. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants.
    Type: Application
    Filed: October 28, 2016
    Publication date: May 3, 2018
    Inventors: James E. Simon, William Reichert
  • Publication number: 20170016808
    Abstract: A clearing agent and mounting solution for microscopy is disclosed comprising at least trichloroethanol and/or derivatives thereof, where the refractive index of the solution is greater than or equal to about 1.3810. Also disclosed are methods of preparing specimens for microscopy.
    Type: Application
    Filed: September 27, 2016
    Publication date: January 19, 2017
    Inventors: James E. Simon, Thomas Villani, Adolfina Koroch
  • Publication number: 20160377514
    Abstract: A clearing agent and mounting solution for microscopy is disclosed comprising (a) trichloroethanol, (b) optionally, trichloroacetic acid, (c) optionally, glycerol and (d) optionally, water, where the refractive index of the solution is greater than or equal to about 1.3810. The solution can further comprise a C1-C6 alcohol, other acids, and/or a stain. The solution can also comprise derivatives and/or analogs of 2,2,2-trichloroethanol and/or trichloroacetic acid. Also disclosed is a method of preparing specimens for microscopy comprising (a) applying a specimen to a microscope slide or a cuvette, (b) applying a quantity of the above solution sufficient to mount the specimen, and (c) optionally applying a cover slip. The solution can be used effectively with stains or dyes, and with fresh, partially dry or dried materials, and for temporary or semi-permanent to permanent mounting.
    Type: Application
    Filed: September 7, 2016
    Publication date: December 29, 2016
    Inventors: James E. Simon, Thomas Villani, Adolfina Koroch
  • Patent number: 9464971
    Abstract: A clearing agent and mounting solution for microscopy is disclosed comprising (a) trichloroethanol, (b) optionally, trichloroacetic acid, (c) optionally, glycerol and (d) optionally, water, where the refractive index of the solution is greater than or equal to about 1.3810. The solution can further comprise a C1-C6 alcohol, other acids, and/or a stain. The solution can also comprise derivatives and/or analogs of 2,2,2-trichloroethanol and/or trichloroacetic acid. Also disclosed is a method of preparing specimens for microscopy comprising (a) applying a specimen to a microscope slide or a cuvette, (b) applying a quantity of the above solution sufficient to mount the specimen, and (c) optionally applying a cover slip. The solution can be used effectively with stains or dyes, and with fresh, partially dry or dried materials, and for temporary or semi-permanent to permanent mounting.
    Type: Grant
    Filed: April 9, 2013
    Date of Patent: October 11, 2016
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: James E. Simon, Thomas Villani, Adolfina Koroch
  • Publication number: 20160213730
    Abstract: The present invention relates to a novel use of naturally occurring plants, mushroom, extracts thereof that exhibit properties as HCV NS5B polymerase inhibitors.
    Type: Application
    Filed: April 1, 2016
    Publication date: July 28, 2016
    Applicant: Rutgers, The State University
    Inventors: James E. Simon, Qingli Wu, Neerja Kaushik-Basu
  • Patent number: 9205119
    Abstract: This disclosure concerns novel methods for preventing or treating neurological or neurodegenerative diseases or disorders by using kombo butter acid enriched extracts derived from the seeds of African nutmeg, the main active compounds isolated from the extracts, namely sargaquinoic acid, sargachromenol, and sargahydroquinoic acid, or synthetic analogs or derivatives thereof, as neuroprotective agents. The methods for preparing the kombo butter or kombo butter acid extracts and the methods for isolating and purifying the active compounds and for preparing their acetylated derivatives are also described.
    Type: Grant
    Filed: March 26, 2010
    Date of Patent: December 8, 2015
    Assignees: Rutgers, The State University of New Jersey, The Regents of the University of California
    Inventors: James E. Simon, Qing-li Wu, Wenbin Deng
  • Publication number: 20150147779
    Abstract: A clearing agent and mounting solution for microscopy is disclosed comprising (a) trichloroethanol, (b) optionally, trichloroacetic acid, (c) optionally, glycerol and (d) optionally, water, where the refractive index of the solution is greater than or equal to about 1.3810. The solution can further comprise a C1-C6 alcohol, other acids, and/or a stain. The solution can also comprise derivatives and/or analogs of 2,2,2-trichloroethanol and/or trichloroacetic acid. Also disclosed is a method of preparing specimens for microscopy comprising (a) applying a specimen to a microscope slide or a cuvette, (b) applying a quantity of the above solution sufficient to mount the specimen, and (c) optionally applying a cover slip. The solution can be used effectively with stains or dyes, and with fresh, partially dry or dried materials, and for temporary or semi-permanent to permanent mounting.
    Type: Application
    Filed: April 9, 2013
    Publication date: May 28, 2015
    Inventors: James E. Simon, Thomas Villani, Adolfina Koroch
  • Patent number: 8642769
    Abstract: This invention provides the methods of separation and identification of a novel type of piperidine flavan alkaloids from an African herbal tea, the leaves of Combretum micranthum commonly known as kinkeliba, and the procedures for preparing the total piperidine flavan alkaloids (TPFA). In particular, this invention relates to the use of the plant extract that may contain TPFA as anti-diabetic agents in treatment of metabolic disorders and other applications related to this new chemical structure and derivatives thereof.
    Type: Grant
    Filed: May 3, 2011
    Date of Patent: February 4, 2014
    Inventors: James E. Simon, Qingli Wu, Cara Welch
  • Publication number: 20130302279
    Abstract: The present invention relates to a novel use of naturally occurring plants, mushroom, extracts thereof that exhibit properties as HCV NS5B polymerase inhibitors.
    Type: Application
    Filed: April 22, 2013
    Publication date: November 14, 2013
    Applicants: University of Medicine & Dentistry of New Jersey, Rutgers, The State University of New Jersey
    Inventors: James E. Simon, Qingli Wu, Neerja Kaushik-Basu
  • Publication number: 20130143921
    Abstract: This invention provides the methods of separation and identification of a novel type of piperidine flavan alkaloids from an African herbal tea, the leaves of Combretum micranthum commonly known as kinkeliba, and the procedures for preparing the total piperidine flavan alkaloids (TPFA). In particular, this invention relates to the use of the plant extract that may contain TPFA as anti-diabetic agents in treatment of metabolic disorders and other applications related to this new chemical structure and derivatives thereof.
    Type: Application
    Filed: May 3, 2011
    Publication date: June 6, 2013
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: James E. Simon, Qingli Wu, Cara Welch
  • Publication number: 20120136047
    Abstract: This disclosure concerns novel methods for preventing or treating neurological or neurodegenerative diseases or disorders by using kombo butter acid enriched extracts derived from the seeds of African nutmeg, the main active compounds isolated from the extracts, namely sargaquinoic acid, sargachromenol, and sargahydroquinoic acid, or synthetic analogs or derivatives thereof, as neuroprotective agents. The methods for preparing the kombo butter or kombo butter acid extracts and the methods for isolating and purifying the active compounds and for preparing their acetylated derivatives are also described.
    Type: Application
    Filed: March 26, 2010
    Publication date: May 31, 2012
    Inventors: James E. Simon, Qing-li Wu, Wenbin Deng
  • Publication number: 20120135094
    Abstract: The present invention relates to bioactivity-guided isolation and identification of bioactive compounds from oregano and mint plants, in particular, rosmarinic acid, oleanolic acid and ursolic acid, and use of these compounds or combinations thereof as anti-inflammatory agents for the treatment of conditions related to pain and inflammation and/or as ingredients of dietary supplements. The invention also relates to optimization of the methods for qualitative and quantitative analysis of the bioactive compounds in oregano and mint plants. In particular, this invention introduces an LC/MS (SIM mode) method to achieve co-quantitation of the three organic acids using a unique tandem column system. In addition, the invention also relates to the methods for recovering various water-soluble polyphenols and triterpenes from aromatic plants.
    Type: Application
    Filed: May 14, 2010
    Publication date: May 31, 2012
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: James E. Simon, Diandian Shen, Hector Rodolfo Juliani, Qingli Wu
  • Patent number: 7371413
    Abstract: The present invention provides methods for reducing the production of nitric oxide, inducible nitric oxide synthase protein and mRNA, and cyclooxygenase-2 protein and mRNA in cells both in vivo and in vitro via the administration of extracts and compounds derived from the seeds of Pycnanthus angolensis Warb. (P. Kombo), commonly known as African nutmeg. These extracts and compounds, namely, kombo butter, kombo butter acid extract, sargaquinoic acid, sargachromenol, and sargahydroquinoic acid, are also useful in the treatment and prevention of a battery of adverse health conditions in human, animal, and avian subjects that are advanced by the production of nitric oxide or its metabolites and/or by the activity of cyclooxygenase-2. Methods for the isolation of kombo butter acid extracts are also provided.
    Type: Grant
    Filed: May 5, 2004
    Date of Patent: May 13, 2008
    Assignees: Rutgers, The State University, BioResources International Inc.
    Inventors: James E. Simon, Mingfu Wang, Kodzo Gbewonyo, Mohamed M. Rafi, Daniel Fahene Acquaye, Yaw Asianowa
  • Patent number: 4807549
    Abstract: In a collapsable elongated article such as a sailboard, the several sections are joined together at respective double chevron surfaces and maintained together by a suitable clamping device. The double chevron surface is used to prevent relative movement in two axes, and the clamping device is used to retain the sections together and thereby prevent relative movement in the third axis.
    Type: Grant
    Filed: July 12, 1984
    Date of Patent: February 28, 1989
    Inventors: Stephen Rhodes, James E. Simon